Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv2528c and Rv2529 are separated by 203 nucleotidesRv2529 and Rv2530c are separated by 0 nucleotidesRv2530c and Rv2530A overlap by 4 nucleotidesRv2530A and Rv2531c are separated by 30 nucleotides Rv2528c: Rv2528c - Probable restriction system protein Mrr, at 2,851,751 to 2,852,671 Rv2528c Rv2529: Rv2529 - Hypothetical protein, at 2,852,875 to 2,854,266 Rv2529 Rv2530c: Rv2530c - Possible toxin VapC39. Contains PIN domain., at 2,854,267 to 2,854,686 Rv2530c Rv2530A: Rv2530A - Possible antitoxin VapB39, at 2,854,683 to 2,854,907 Rv2530A Rv2531c: Rv2531c - Probable amino acid decarboxylase, at 2,854,938 to 2,857,781 Rv2531c
Group Condition Rv2528c Rv2529 Rv2530c Rv2530A Rv2531c
stress 7H9 with Ofloxacin 0.8 ug/mL -0.3 -0.7 N.D. N.D. +0.1
carbon source Glycerol (C) -0.2 -0.3 N.D. N.D. -0.3
stress 7H9 with Delamanid 0.236 ug/mL -0.1 -0.6 N.D. N.D. +0.0
stress 7H9 with Hygromycin B 0.0095 mM -0.3 -0.3 N.D. N.D. -0.1
stress 7H9 with para-aminosalicylic 0.086 ug/mL -0.1 -0.4 N.D. N.D. -0.1
stress 7H9 with Dimethyl Sulfoxide 1 vol% -0.3 -0.5 N.D. N.D. +0.1
carbon source propionate (C) -0.6 -0.2 N.D. N.D. +0.2
stress 7H9 with para-aminosalicylic 0.086 ug/mL +0.1 -0.7 N.D. N.D. +0.0
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.5 +0.3 N.D. N.D. -0.1
carbon source casaminos 1 mg/mL (C) -0.3 -0.1 N.D. N.D. +0.2
nitrogen source L-Asparagine 10 mM (N) -0.3 +0.3 N.D. N.D. -0.1
stress 7H9 with Rifampicin 0.014 ug/mL +0.3 -0.4 N.D. N.D. -0.1
carbon source D-Trehalose 10 mM (C) -0.4 +0.2 N.D. N.D. -0.0
no stress control no stress control -0.3 +0.3 N.D. N.D. -0.0
carbon source L-Lactate 10 mM (C) -0.2 +0.4 N.D. N.D. -0.1
stress 7H9 with Hygromycin B 0.0095 mM +0.4 -0.2 N.D. N.D. -0.1
stress 7H9 with Meropenem 9.6 ug/mL -0.3 +0.4 N.D. N.D. +0.1
nitrogen source L-Valine 10 mM (N) +0.4 -0.1 N.D. N.D. -0.1
no stress control no stress control +0.4 -0.1 N.D. N.D. -0.0
no stress control no stress control -0.2 +0.3 N.D. N.D. +0.2
carbon source casaminos 1 mg/mL (C) -0.2 +0.5 N.D. N.D. +0.1
carbon source L-Lactate 10 mM (C) -0.1 +0.5 N.D. N.D. +0.0
carbon source Stearic 100 uM (C) -0.1 +0.5 N.D. N.D. +0.0
carbon source L-Asparagine (C) +0.5 +0.0 N.D. N.D. +0.1
stress 7H9 with Sulfaquinoxaline 0.097 mM +0.3 +0.3 N.D. N.D. +0.0
nitrogen source L-Alanine 10 mM (N) +0.3 +0.1 N.D. N.D. +0.2
stress 7H9 with Rifampicin 0.00045 ug/mL +0.2 +0.5 N.D. N.D. -0.0
stress 7H9 with Isoniazid 0.025 ug/mL +0.6 +0.2 N.D. N.D. -0.1
stress 7H9 with Levofloxacin 0.3 ug/mL +0.3 +0.4 N.D. N.D. +0.1
stress 7H9 with Ethionamide 0.1 ug/mL +0.1 +0.8 N.D. N.D. -0.1
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