Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv2401 and Rv2401A overlap by 16 nucleotidesRv2401A and Rv2402 are separated by 283 nucleotidesRv2402 and Rv2403c are separated by 77 nucleotidesRv2403c and Rv2404c overlap by 4 nucleotides Rv2401: Rv2401 - Hypothetical protein, at 2,697,728 to 2,698,057 Rv2401 Rv2401A: Rv2401A - Possible conserved membrane protein, at 2,698,042 to 2,698,245 Rv2401A Rv2402: Rv2402 - Conserved protein, at 2,698,529 to 2,700,457 Rv2402 Rv2403c: Rv2403c - Probable conserved lipoprotein LppR, at 2,700,535 to 2,701,290 Rv2403c Rv2404c: Rv2404c - Probable GTP-binding protein LepA (GTP-binding elongation factor), at 2,701,287 to 2,703,248 Rv2404c
Group Condition Rv2401 Rv2401A Rv2402 Rv2403c Rv2404c
stress 7H9 with Hygromycin B 0.0095 mM N.D. N.D. -0.1 -0.3 -0.7
no stress control no stress control N.D. N.D. -0.2 -0.6 -0.2
carbon source L-Asparagine (C) N.D. N.D. -0.1 -0.6 +0.2
nitrogen source L-Glutamic 10 mM (N) N.D. N.D. +0.0 -0.8 +0.3
nitrogen source L-Alanine 10 mM (N) N.D. N.D. +0.2 -0.6 +0.2
nitrogen source L-Glutamine 10 mM (N) N.D. N.D. -0.0 -0.4 +0.6
stress 7H9 with Sulfamethizole 0.026 mM N.D. N.D. +0.1 -0.4 +0.5
nitrogen source L-Glutamine 10 mM (N) N.D. N.D. +0.0 -0.4 +0.7
nitrogen source L-Asparagine 10 mM (N) N.D. N.D. -0.1 -0.2 +0.8
carbon source Glycerol (C) N.D. N.D. +0.1 -0.1 +0.8
nitrogen source L-Asparagine 10 mM (N) N.D. N.D. -0.2 +0.0 +0.9
carbon source L-Glutamine (C) N.D. N.D. +0.1 -0.1 +0.7
nitrogen source L-Aspartic Acid 10 mM (N) N.D. N.D. +0.0 -0.1 +0.8
carbon source Glycerol (C) N.D. N.D. +0.0 +0.1 +0.7
stress 7H9 with Streptomycin 0.178 ug/mL N.D. N.D. +0.2 +0.3 +0.4
stress 7H9 with Streptomycin 0.178 ug/mL N.D. N.D. +0.1 +0.3 +0.5
stress 7H9 with Rifampicin 0.00045 ug/mL N.D. N.D. +0.1 +0.5 +0.4
no stress control no stress control N.D. N.D. +0.3 +0.5 +0.3
no stress control no stress control N.D. N.D. +0.4 +0.3 +0.4
stress 7H9 with Ethionamide 0.1 ug/mL N.D. N.D. -0.0 +0.5 +0.5
stress 7H9 with Rifampicin 0.014 ug/mL N.D. N.D. +0.0 +0.0 +1.0
nitrogen source Glycine 10 mM (N) N.D. N.D. +0.1 +0.4 +0.7
stress 7H9 with para-aminosalicylic 0.086 ug/mL N.D. N.D. -0.0 +0.6 +0.6
stress 7H9 with Rifampicin 0.014 ug/mL N.D. N.D. +0.1 +0.2 +0.9
stress 7H9 with Ofloxacin 0.8 ug/mL N.D. N.D. +0.1 +0.6 +0.5
stress 7H9 with Ofloxacin 0.8 ug/mL N.D. N.D. +0.2 +0.4 +0.8
stress 7H9 with Levofloxacin 0.3 ug/mL N.D. N.D. +0.2 +0.5 +0.8
stress 7H9 with Ethionamide 0.1 ug/mL N.D. N.D. +0.2 +0.8 +0.6
stress 7H9 with Isoniazid 0.025 ug/mL N.D. N.D. +0.1 +0.4 +3.0
stress 7H9 with Isoniazid 0.025 ug/mL N.D. N.D. +0.2 +0.5 +3.2
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