Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

Add gene:

Number of genes on each side:  

Top 30 experiments (either direction), sorted by average fitness

Or view all 101 experiments or choose conditions or try the comparative fitness browser

500 ntRv2332 and Rv2333c overlap by 47 nucleotidesRv2333c and Rv2334 are separated by 474 nucleotidesRv2334 and Rv2335 are separated by 3 nucleotidesRv2335 and Rv2336 are separated by 415 nucleotides Rv2332: Rv2332 - Probable [NAD] dependent malate oxidoreductase Mez (malic enzyme) (NAD-malic enzyme) (malate dehydrogenase (oxaloacetate decarboxylating)) (pyruvic-malic carboxylase) (NAD-me), at 2,605,108 to 2,606,754 Rv2332 Rv2333c: Rv2333c - Integral membrane drug efflux protein Stp, at 2,606,708 to 2,608,321 Rv2333c Rv2334: Rv2334 - Cysteine synthase a CysK1 (O-acetylserine sulfhydrylase A) (O-acetylserine (thiol)-lyase A) (CSASE A), at 2,608,796 to 2,609,728 Rv2334 Rv2335: Rv2335 - Probable serine acetyltransferase CysE (sat), at 2,609,732 to 2,610,421 Rv2335 Rv2336: Rv2336 - Hypothetical protein, at 2,610,837 to 2,611,805 Rv2336
Group Condition Rv2332 Rv2333c Rv2334 Rv2335 Rv2336
stress 7H9 with Dimethyl Sulfoxide 1 vol% -0.0 -0.2 N.D. -2.7 +0.0
stress 7H9 with para-aminosalicylic 0.086 ug/mL -0.1 -0.2 N.D. -2.2 -0.0
no stress control no stress control +0.1 -0.1 N.D. -2.7 +0.1
no stress control no stress control +0.2 +0.0 N.D. -2.1 -0.1
stress 7H9 with Dimethyl Sulfoxide 1 vol% +0.0 -0.2 N.D. -1.4 -0.2
carbon source heptadecanoic 250 uM (C) +0.0 +0.0 N.D. -1.6 -0.1
stress 7H9 with Pretomanid 0.213 ug/mL -0.1 -0.1 N.D. -1.4 +0.1
no stress control no stress control -0.1 -0.1 N.D. -1.4 +0.0
no stress control no stress control -0.1 -0.1 N.D. -1.3 +0.1
stress 7H9 with Delamanid 0.236 ug/mL +0.0 -0.0 N.D. -1.2 -0.1
stress 7H9 with Sulfamethizole 0.026 mM +0.0 +0.0 N.D. -1.3 +0.1
stress 7H9 with Rifampicin 0.00045 ug/mL +0.0 -0.0 N.D. -1.5 +0.4
stress 7H9 with Rifampicin 0.00045 ug/mL +0.2 +0.1 N.D. -1.4 +0.0
stress 7H9 with Pretomanid 0.213 ug/mL +0.0 -0.2 N.D. -0.6 -0.2
nitrogen source Glycine 10 mM (N) +0.0 -0.1 N.D. -1.0 +0.1
stress 7H9 with Streptomycin 0.178 ug/mL +0.0 -0.2 N.D. -0.9 +0.1
stress 7H9 with Streptomycin 0.178 ug/mL +0.2 -0.1 N.D. -1.1 +0.1
stress 7H9 with Ethionamide 0.1 ug/mL +0.1 -0.0 N.D. -0.6 -0.3
stress 7H9 with Linezolid 0.44 ug/mL +0.0 -0.2 N.D. -0.9 +0.3
no stress control no stress control +0.1 -0.1 N.D. -0.8 +0.0
stress 7H9 with para-aminosalicylic 0.086 ug/mL +0.0 -0.2 N.D. -0.8 +0.3
no stress control no stress control +0.1 -0.0 N.D. -0.9 +0.2
stress 7H9 with Clofazimine 0.45 ug/mL +0.0 +0.1 N.D. -1.1 +0.5
carbon source Glycerol (C) +0.1 +0.1 N.D. -0.8 +0.2
stress 7H9 with Isoniazid 0.025 ug/mL +0.3 -0.0 N.D. -0.8 +0.1
stress 7H9 with Clofazimine 0.45 ug/mL +0.1 +0.1 N.D. -1.0 +0.5
stress 7H9 with Ethionamide 0.1 ug/mL -0.0 +0.2 N.D. -0.6 +0.3
stress 7H9 with Meropenem 9.6 ug/mL +0.3 +0.2 N.D. +0.7 -0.2
stress 7H9 with Rifampicin 0.014 ug/mL +0.2 +0.1 N.D. +0.5 +0.3
nitrogen source L-Valine 10 mM (N) +0.1 +0.1 N.D. +1.0 +0.3
remove
Rv2332
plot		 remove
Rv2333c
plot		 remove
Rv2334		 remove
Rv2335
plot		 remove
Rv2336
plot