Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

Add gene:

Number of genes on each side:  

Top 30 experiments (either direction), sorted by average fitness

Or view all 101 experiments or choose conditions or try the comparative fitness browser

500 ntRv2317 and Rv2318 overlap by 4 nucleotidesRv2318 and Rv2319c are separated by 7 nucleotidesRv2319c and Rv2320c overlap by 4 nucleotidesRv2320c and Rv2321c are separated by 0 nucleotides Rv2317: Rv2317 - Probable sugar-transport integral membrane protein ABC transporter UspB, at 2,589,697 to 2,590,521 Rv2317 Rv2318: Rv2318 - Probable periplasmic sugar-binding lipoprotein UspC, at 2,590,518 to 2,591,840 Rv2318 Rv2319c: Rv2319c - Universal stress protein family protein, at 2,591,848 to 2,592,726 Rv2319c Rv2320c: Rv2320c - Probable cationic amino acid transport integral membrane protein RocE, at 2,592,723 to 2,594,153 Rv2320c Rv2321c: Rv2321c - Probable ornithine aminotransferase (C-terminus part) RocD2 (ornithine--oxo-acid aminotransferase), at 2,594,154 to 2,594,699 Rv2321c
Group Condition Rv2317 Rv2318 Rv2319c Rv2320c Rv2321c
stress 7H9 with Ethionamide 0.1 ug/mL -3.8 +0.1 +0.4 -0.0 +0.0
stress 7H9 with Linezolid 0.44 ug/mL -1.4 -0.1 +0.4 +0.0 -1.1
stress 7H9 with Rifampicin 0.00045 ug/mL -0.5 +0.1 -0.0 +0.3 -1.8
stress 7H9 with Ethambutol 0.75 ug/mL -0.8 -0.3 +0.3 +0.0 -1.1
carbon source Valeric 10 mM (C) -0.8 -0.3 -0.2 +0.1 -0.6
stress 7H9 with Hygromycin B 0.0095 mM -1.5 -0.3 -0.4 +0.1 +0.4
stress 7H9 with Clofazimine 0.45 ug/mL -1.1 +0.2 +0.1 -0.0 -0.7
stress 7H9 with Hygromycin B 0.0095 mM -0.8 +0.3 -0.6 +0.0 +0.0
carbon source Stearic 100 uM (C) -0.6 -0.2 +0.4 -0.0 -0.7
stress 7H9 with Ethionamide 0.1 ug/mL -1.3 +0.3 +0.1 -0.0 -0.2
stress 7H9 with Delamanid 0.236 ug/mL -0.5 +0.2 -0.3 +0.2 -0.6
carbon source L-Lactate 10 mM (C) -0.8 -0.0 +0.5 -0.2 -0.4
stress 7H9 with Ofloxacin 0.8 ug/mL -0.9 +0.3 +0.3 -0.1 -0.3
no stress control no stress control -0.9 +0.1 +0.6 +0.1 -0.5
carbon source casaminos 1 mg/mL (C) +0.2 -0.5 +0.5 +0.1 -0.4
carbon source D,L-Malic Acid 10 mM (C) +0.1 +0.2 +0.7 -0.1 -0.9
nitrogen source Glycine 10 mM (N) -0.6 -0.1 +0.8 -0.1 +0.1
stress 7H9 with Clarithromycin 0.967 ug/mL +0.6 +0.2 -0.3 +0.3 -0.3
carbon source L-Glutamine (C) +0.7 +0.2 +0.1 +0.1 -0.6
stress 7H9 with para-aminosalicylic 0.086 ug/mL -0.3 +0.7 +0.2 +0.1 +0.5
nitrogen source L-Valine 10 mM (N) +0.9 -0.3 +0.5 -0.1 +0.2
nitrogen source L-Glutamic 10 mM (N) +0.9 -0.2 +0.1 -0.2 +0.8
nitrogen source L-Serine 10 mM (N) +0.4 -0.2 +0.5 +0.1 +0.8
stress 7H9 with Clofazimine 0.45 ug/mL +1.2 +0.1 +0.5 +0.2 -0.4
stress 7H9 with Clofazimine 0.072 ug/mL +1.6 +0.2 +0.4 +0.0 -0.6
carbon source L-Lactate 10 mM (C) +1.1 +0.2 +0.8 +0.0 -0.5
nitrogen source L-Glutamine 10 mM (N) +0.6 +0.0 +0.2 +0.0 +0.8
carbon source L-Asparagine (C) +0.6 +0.4 +0.3 +0.1 +0.5
no stress control no stress control +0.1 +0.6 +0.0 -0.0 +1.3
stress 7H9 with para-aminosalicylic 0.086 ug/mL +1.0 +0.6 -0.0 +0.4 +0.1
remove
Rv2317
plot		 remove
Rv2318
plot		 remove
Rv2319c		 remove
Rv2320c
plot		 remove
Rv2321c
plot