Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv2286c and Rv2287 are separated by 133 nucleotidesRv2287 and Rv2288 overlap by 4 nucleotidesRv2288 and Rv2289 overlap by 31 nucleotidesRv2289 and Rv2290 are separated by 141 nucleotides Rv2286c: Rv2286c - Conserved hypothetical protein, at 2,558,877 to 2,559,569 Rv2286c Rv2287: Rv2287 - Probable conserved integral membrane transport protein YjcE, at 2,559,703 to 2,561,331 Rv2287 Rv2288: Rv2288 - Hypothetical protein, at 2,561,328 to 2,561,705 Rv2288 Rv2289: Rv2289 - Probable CDP-diacylglycerol pyrophosphatase Cdh (CDP-diacylglycerol diphosphatase) (CDP-diacylglycerol phosphatidylhydrolase), at 2,561,675 to 2,562,457 Rv2289 Rv2290: Rv2290 - Probable conserved lipoprotein LppO, at 2,562,599 to 2,563,114 Rv2290
Group Condition Rv2286c Rv2287 Rv2288 Rv2289 Rv2290
stress 7H9 with Cumene hydroperoxide 0.05 mM -0.1 -0.5 N.D. -0.3 -0.1
nitrogen source Ammonium chloride 10mM (N) -0.1 -0.4 N.D. -0.3 -0.0
nitrogen source L-Glutamic 10 mM (N) -0.4 -0.4 N.D. +0.1 -0.1
stress 7H9 with Norfloxacin 0.125 mM -0.2 -0.3 N.D. -0.0 -0.3
stress 7H9 with Meropenem 9.6 ug/mL -0.2 -0.3 N.D. +0.2 -0.4
no stress control no stress control -0.4 -0.0 N.D. +0.1 -0.3
stress 7H9 with methylglyoxal 1.2 mM +0.1 +0.1 N.D. -0.3 -0.4
stress 7H9 with nitrite 5 mM -0.5 +0.1 N.D. +0.1 -0.3
stress 7H9 with copper (II) chloride 0.08 mM -0.6 -0.1 N.D. +0.3 -0.1
no stress control no stress control -0.0 -0.6 N.D. -0.1 +0.2
stress 7H9 with nitrite 2.5 mM -0.4 -0.1 N.D. +0.2 -0.1
stress 7H9 with copper (II) chloride 0.08 mM -0.5 -0.0 N.D. +0.4 -0.2
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -0.1 -0.3 N.D. +0.3 -0.2
stress 7H9 with Chloramphenicol 0.01 mM +0.2 -0.2 N.D. -0.3 +0.0
no stress control no stress control -0.1 -0.5 N.D. +0.3 +0.1
stress 7H9 with Dicloxacillin 0.0069 mM +0.2 -0.4 N.D. -0.0 +0.2
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.5 -0.3 N.D. -0.1 -0.1
stress 7H9 with Phenazine methosulfate 0.0054 mM -0.3 -0.2 N.D. +0.3 +0.2
stress 7H9 with Geneticin G418 0.35 mM +0.2 -0.4 N.D. +0.4 -0.1
no stress control no stress control -0.2 -0.4 N.D. +0.4 +0.3
stress 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM -0.3 +0.1 N.D. +0.2 +0.2
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 +0.3 -0.2 N.D. +0.2 -0.0
stress 7H9 with Levofloxacin 0.3 ug/mL +0.4 +0.3 N.D. -0.3 -0.1
stress 7H9 with hypochlorite 0.4 vol% +0.3 -0.3 N.D. +0.0 +0.4
carbon source D-Lactate 10 mM (C) -0.2 +0.2 N.D. +0.3 +0.1
stress 7H9 with Dodecyl Sulfate 0.02 vol% -0.2 +0.4 N.D. +0.4 -0.1
stress 7H9 with Formaldehyde 0.23 mM +0.2 +0.3 N.D. -0.2 +0.2
stress 7H9 with Ofloxacin 0.8 ug/mL +0.4 +0.2 N.D. +0.1 -0.1
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.6 -0.1 N.D. +0.1 +0.2
stress 7H9 with Geneticin G418 0.35 mM +0.1 +0.2 N.D. +0.4 +0.1
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