Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv2153c and Rv2154c overlap by 4 nucleotidesRv2154c and Rv2155c are separated by 11 nucleotidesRv2155c and Rv2156c are separated by 1 nucleotidesRv2156c and Rv2157c overlap by 4 nucleotides Rv2153c: Rv2153c - Probable UPD-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol-N-acetylglucosamine transferase MurG, at 2,412,119 to 2,413,351 Rv2153c Rv2154c: Rv2154c - FtsW-like protein FtsW, at 2,413,348 to 2,414,922 Rv2154c Rv2155c: Rv2155c - Probable UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD, at 2,414,934 to 2,416,394 Rv2155c Rv2156c: Rv2156c - Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX, at 2,416,396 to 2,417,475 Rv2156c Rv2157c: Rv2157c - Probable UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase MurF, at 2,417,472 to 2,419,004 Rv2157c
Group Condition Rv2153c Rv2154c Rv2155c Rv2156c Rv2157c
stress 7H9 with Rifampicin 0.014 ug/mL N.D. -1.2 N.D. N.D. N.D.
carbon source D-Trehalose 10 mM (C) N.D. -1.2 N.D. N.D. N.D.
carbon source D-Lactate 10 mM (C) N.D. -1.2 N.D. N.D. N.D.
stress 7H9 with Clofazimine 0.45 ug/mL N.D. -1.1 N.D. N.D. N.D.
stress 7H9 with Clofazimine 0.072 ug/mL N.D. -1.1 N.D. N.D. N.D.
carbon source L-Lactate 10 mM (C) N.D. -1.1 N.D. N.D. N.D.
carbon source casaminos 1 mg/mL (C) N.D. -1.0 N.D. N.D. N.D.
carbon source pyruvate (C) N.D. -1.0 N.D. N.D. N.D.
carbon source L-Lactate 10 mM (C) N.D. -1.0 N.D. N.D. N.D.
carbon source heptadecanoic 250 uM (C) N.D. -1.0 N.D. N.D. N.D.
stress 7H9 with Clofazimine 0.072 ug/mL N.D. -1.0 N.D. N.D. N.D.
carbon source propionate (C) N.D. -1.0 N.D. N.D. N.D.
stress 7H9 with Hygromycin B 0.0095 mM N.D. -1.0 N.D. N.D. N.D.
stress 7H9 with Bedaquiline 0.15 ug/mL N.D. -0.9 N.D. N.D. N.D.
carbon source casaminos 1 mg/mL (C) N.D. -0.9 N.D. N.D. N.D.
stress 7H9 with Hygromycin B 0.0095 mM N.D. -0.9 N.D. N.D. N.D.
carbon source propionate (C) N.D. -0.8 N.D. N.D. N.D.
stress 7H9 with Bedaquiline 0.15 ug/mL N.D. -0.8 N.D. N.D. N.D.
nitrogen source Glycine 10 mM (N) N.D. -0.8 N.D. N.D. N.D.
stress 7H9 with Pretomanid 0.213 ug/mL N.D. -0.8 N.D. N.D. N.D.
stress 7H9 with Rifampicin 0.00045 ug/mL N.D. -0.8 N.D. N.D. N.D.
carbon source L-Asparagine (C) N.D. -0.8 N.D. N.D. N.D.
carbon source D-Lactate 10 mM (C) N.D. -0.8 N.D. N.D. N.D.
carbon source L-Asparagine (C) N.D. -0.7 N.D. N.D. N.D.
carbon source Valeric 10 mM (C) N.D. -0.7 N.D. N.D. N.D.
carbon source butyrate 10 mM (C) N.D. -0.7 N.D. N.D. N.D.
stress 7H9 with Dimethyl Sulfoxide 1 vol% N.D. -0.7 N.D. N.D. N.D.
nitrogen source L-Alanine 10 mM (N) N.D. +0.7 N.D. N.D. N.D.
stress 7H9 with Isoniazid 0.025 ug/mL N.D. +1.2 N.D. N.D. N.D.
stress 7H9 with Isoniazid 0.025 ug/mL N.D. +1.8 N.D. N.D. N.D.
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