Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv2099c and Rv2100 are separated by 182 nucleotidesRv2100 and Rv2101 are separated by 198 nucleotidesRv2101 and Rv2102 are separated by 109 nucleotidesRv2102 and Rv2103c overlap by 22 nucleotides Rv2099c: Rv2099c - PE family protein PE21, at 2,358,033 to 2,358,206 Rv2099c Rv2100: Rv2100 - Conserved hypothetical protein, at 2,358,389 to 2,360,041 Rv2100 Rv2101: Rv2101 - Probable helicase HelZ, at 2,360,240 to 2,363,281 Rv2101 Rv2102: Rv2102 - Conserved hypothetical protein, at 2,363,391 to 2,364,107 Rv2102 Rv2103c: Rv2103c - Possible toxin VapC37. Contains PIN domain., at 2,364,086 to 2,364,520 Rv2103c
Group Condition Rv2099c Rv2100 Rv2101 Rv2102 Rv2103c
stress 7H9 with Isoniazid 0.025 ug/mL -1.9 +0.2 -0.3 +0.0 +0.2
stress 7H9 with Moxifloxacin 0.121 ug/mL -2.0 +0.1 +0.3 -0.3 +0.2
carbon source acetate (C) -1.0 +0.1 -0.0 -0.2 -0.5
stress 7H9 with Ethionamide 0.1 ug/mL -1.6 +0.1 -0.0 -0.3 +0.4
stress 7H9 with Isoniazid 0.025 ug/mL -1.5 +0.3 -0.2 -0.7 +0.8
carbon source L-Asparagine (C) -0.9 -0.1 -0.0 +0.1 -0.5
stress 7H9 with Clofazimine 0.45 ug/mL -1.1 -0.2 -0.1 +0.2 -0.1
nitrogen source L-Aspartic Acid 10 mM (N) -0.2 -0.0 -0.1 -0.4 -0.4
stress 7H9 with para-aminosalicylic 0.086 ug/mL -0.5 -0.0 -0.0 -0.1 -0.4
carbon source butyrate 10 mM (C) -0.3 -0.1 -0.0 -0.6 +0.0
stress 7H9 with Ethionamide 0.1 ug/mL -1.1 +0.1 -0.0 -0.4 +0.7
carbon source Palmitic 100 uM (C) -0.8 -0.0 +0.1 +0.3 -0.2
stress 7H9 with Clofazimine 0.45 ug/mL -0.5 +0.0 -0.3 +0.2 -0.1
stress 7H9 with Hygromycin B 0.0095 mM -0.3 -0.2 +0.0 +0.3 -0.4
no stress control no stress control -1.0 +0.1 -0.0 +0.1 +0.3
no stress control no stress control +0.3 -0.0 +0.0 -0.4 -0.3
no stress control no stress control -0.6 +0.0 -0.1 +0.4 -0.3
carbon source Palmitic 100 uM (C) -0.5 -0.1 +0.1 -0.1 +0.3
stress 7H9 with Ofloxacin 0.8 ug/mL -1.3 +0.1 +0.5 +0.3 +0.2
stress 7H9 with Moxifloxacin 0.121 ug/mL -1.2 +0.0 +0.2 +0.5 +0.3
carbon source propionate (C) -0.6 +0.0 -0.0 +0.2 +0.3
carbon source D-Trehalose 10 mM (C) -0.4 +0.0 -0.1 +0.2 +0.4
stress 7H9 with Rifampicin 0.014 ug/mL -0.6 -0.1 -0.1 +0.4 +0.4
nitrogen source L-Glutamine 10 mM (N) +0.4 -0.2 +0.1 +0.1 -0.3
stress 7H9 with Ofloxacin 0.8 ug/mL -1.4 +0.2 +0.5 +0.5 +0.6
stress 7H9 with Ethambutol 0.75 ug/mL +0.2 +0.0 -0.1 +0.7 +0.0
stress 7H9 with Rifampicin 0.00045 ug/mL +0.6 -0.0 -0.1 +0.4 +0.1
carbon source D-Lactate 10 mM (C) +0.6 -0.0 +0.1 +0.5 -0.1
stress 7H9 with Levofloxacin 0.3 ug/mL -0.8 +0.1 +0.6 +0.7 +0.6
carbon source L-Lactate 10 mM (C) +0.4 +0.2 +0.2 +0.3 +0.2
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