Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv2089c and Rv2090 are separated by 48 nucleotidesRv2090 and Rv2091c are separated by 3 nucleotidesRv2091c and Rv2092c are separated by 41 nucleotidesRv2092c and Rv2093c are separated by 48 nucleotides Rv2089c: Rv2089c - Dipeptidase PepE, at 2,346,197 to 2,347,324 Rv2089c Rv2090: Rv2090 - Probable 5'-3' exonuclease, at 2,347,373 to 2,348,554 Rv2090 Rv2091c: Rv2091c - Probable membrane protein, at 2,348,558 to 2,349,292 Rv2091c Rv2092c: Rv2092c - ATP-dependent DNA helicase HelY, at 2,349,334 to 2,352,054 Rv2092c Rv2093c: Rv2093c - Sec-independent protein translocase transmembrane protein TatC, at 2,352,103 to 2,353,029 Rv2093c
Group Condition Rv2089c Rv2090 Rv2091c Rv2092c Rv2093c
carbon source acetate (C) -1.4 +0.1 -0.3 -0.3 N.D.
stress 7H9 with Rifampicin 0.014 ug/mL -0.0 -0.3 -1.6 +0.1 N.D.
stress 7H9 with Rifampicin 0.00045 ug/mL +0.0 -0.3 -1.4 +0.1 N.D.
stress 7H9 with Rifampicin 0.014 ug/mL +0.3 -0.4 -1.6 +0.2 N.D.
nitrogen source L-Glutamic 10 mM (N) -0.7 -0.2 -0.5 -0.0 N.D.
stress 7H9 with Bedaquiline 0.15 ug/mL -0.1 -0.1 -1.1 -0.0 N.D.
nitrogen source L-Asparagine 10 mM (N) -0.5 -0.0 -0.9 +0.1 N.D.
stress 7H9 with Bedaquiline 0.15 ug/mL +0.1 -0.2 -1.2 +0.0 N.D.
carbon source D-Trehalose 10 mM (C) -0.2 +0.1 -1.1 +0.1 N.D.
stress 7H9 with Clarithromycin 0.967 ug/mL -0.4 +0.2 -0.5 -0.5 N.D.
nitrogen source L-Alanine 10 mM (N) -0.0 -0.2 -1.0 +0.1 N.D.
stress 7H9 with Hygromycin B 0.0095 mM -0.7 -0.5 +0.1 +0.1 N.D.
carbon source D-Glucose (C) -0.2 +0.1 -1.0 -0.0 N.D.
nitrogen source L-Serine 10 mM (N) +0.3 -0.4 -0.9 +0.0 N.D.
nitrogen source L-Alanine 10 mM (N) -0.3 +0.0 -0.9 +0.2 N.D.
carbon source L-Aspartic Acid (C) -0.4 +0.0 -0.6 +0.1 N.D.
stress 7H9 with Rifampicin 0.00045 ug/mL +0.2 -0.2 -0.9 +0.1 N.D.
nitrogen source Glycine 10 mM (N) +0.2 +0.1 -1.1 +0.1 N.D.
nitrogen source L-Asparagine 10 mM (N) +0.3 -0.1 -1.0 +0.2 N.D.
stress 7H9 with Isoniazid 0.025 ug/mL -0.7 +0.1 +0.3 -0.3 N.D.
nitrogen source L-Serine 10 mM (N) +0.3 +0.1 -0.9 +0.1 N.D.
carbon source propionate (C) -0.8 -0.1 +0.4 +0.2 N.D.
stress 7H9 with Isoniazid 0.025 ug/mL -0.0 +0.3 +0.1 -0.7 N.D.
carbon source D-Trehalose 10 mM (C) +0.5 +0.1 -0.8 -0.1 N.D.
stress 7H9 with Ofloxacin 0.8 ug/mL -0.6 +0.2 +0.3 +0.1 N.D.
stress 7H9 with Sulfamethizole 0.026 mM -0.4 -0.1 +0.9 +0.2 N.D.
carbon source L-Lactate 10 mM (C) +0.6 +0.6 -0.7 -0.0 N.D.
stress 7H9 with Ethionamide 0.1 ug/mL +0.1 +0.4 +0.5 -0.3 N.D.
stress 7H9 with Linezolid 0.44 ug/mL +0.2 -0.2 +0.0 +0.8 N.D.
stress 7H9 with Sulfamethizole 0.026 mM -0.2 +0.1 +1.1 +0.2 N.D.
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