Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv2045c and Rv2046 are separated by 48 nucleotidesRv2046 and Rv2047c are separated by 36 nucleotidesRv2047c and Rv2048c are separated by 4 nucleotidesRv2048c and Rv2049c are separated by 306 nucleotides Rv2045c: Rv2045c - Carboxylesterase LipT, at 2,289,685 to 2,291,220 Rv2045c Rv2046: Rv2046 - Probable lipoprotein LppI, at 2,291,269 to 2,291,925 Rv2046 Rv2047c: Rv2047c - Conserved hypothetical protein, at 2,291,962 to 2,294,526 Rv2047c Rv2048c: Rv2048c - Polyketide synthase Pks12, at 2,294,531 to 2,306,986 Rv2048c Rv2049c: Rv2049c - Conserved hypothetical protein, at 2,307,293 to 2,307,517 Rv2049c
Group Condition Rv2045c Rv2046 Rv2047c Rv2048c Rv2049c
stress 7H9 with Clofazimine 0.45 ug/mL +0.1 -0.1 -3.8 -2.7 -0.1
stress 7H9 with Clofazimine 0.45 ug/mL -0.0 +0.6 -3.4 -2.8 +0.3
nitrogen source L-Serine 10 mM (N) +0.1 -0.0 -2.7 -2.6 +0.2
nitrogen source L-Asparagine 10 mM (N) -0.0 +0.2 -2.2 -2.7 -0.1
nitrogen source L-Asparagine 10 mM (N) +0.3 +0.3 -2.6 -2.6 +0.1
nitrogen source L-Serine 10 mM (N) +0.1 +0.0 -2.4 -2.2 +0.0
nitrogen source L-Aspartic Acid 10 mM (N) +0.1 +0.3 -2.5 -2.6 +0.4
carbon source casaminos 1 mg/mL (C) -0.2 -0.9 -1.4 -0.9 -0.8
carbon source Stearic 100 uM (C) +0.0 -0.4 -1.9 -1.4 -0.5
carbon source L-Lactate 10 mM (C) -0.1 -0.6 -1.8 -1.5 -0.2
carbon source L-Asparagine (C) -0.2 +0.3 -1.9 -1.7 -0.5
carbon source Stearic 100 uM (C) +0.0 -0.4 -1.7 -1.4 -0.6
carbon source L-Lactate 10 mM (C) -0.1 -0.6 -1.8 -1.4 -0.1
carbon source L-Aspartic Acid (C) -0.1 -0.1 -1.8 -1.6 -0.3
nitrogen source L-Aspartic Acid 10 mM (N) +0.1 -0.0 -2.1 -1.9 -0.0
carbon source D-Glucose (C) -0.0 -0.1 -1.9 -1.6 -0.2
carbon source D-Trehalose 10 mM (C) -0.1 -0.7 -1.5 -1.1 -0.3
carbon source Glycerol (C) +0.1 -0.2 -1.7 -2.1 +0.1
carbon source butyrate 10 mM (C) +0.2 -0.0 -1.7 -1.5 -0.8
carbon source L-Asparagine (C) +0.1 -0.2 -2.0 -1.8 +0.2
carbon source D,L-Malic Acid 10 mM (C) -0.3 -0.6 -1.6 -1.3 +0.3
carbon source D,L-Malic Acid 10 mM (C) -0.2 -0.6 -1.6 -1.3 +0.2
carbon source Glycerol (C) -0.1 +0.0 -1.6 -1.9 +0.2
carbon source casaminos 1 mg/mL (C) +0.0 -1.0 -1.4 -1.3 +0.4
nitrogen source L-Alanine 10 mM (N) -0.3 +0.7 -1.9 -1.5 -0.3
nitrogen source Glycine 10 mM (N) +0.3 +0.3 -2.2 -1.8 +0.3
carbon source L-Aspartic Acid (C) -0.2 +0.6 -1.9 -1.7 +0.1
carbon source pyruvate (C) -0.1 +0.1 -1.8 -1.6 +0.3
stress 7H9 with Clofazimine 0.072 ug/mL -0.2 +0.5 -1.6 -1.3 -0.2
nitrogen source L-Alanine 10 mM (N) -0.0 +0.2 -1.6 -1.6 +0.4
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