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Protein
Homologs
Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv2024c and Rv2025c are separated by 509 nucleotides
Rv2025c and Rv2026c are separated by 114 nucleotides
Rv2026c and Rv2027c are separated by 39 nucleotides
Rv2027c and Rv2028c are separated by 60 nucleotides
Rv2024c: Rv2024c - Conserved hypothetical protein, at 2,268,693 to 2,270,240
Rv2024c
Rv2025c: Rv2025c - Conserved membrane protein, at 2,270,750 to 2,271,748
Rv2025c
Rv2026c: Rv2026c - Universal stress protein family protein, at 2,271,863 to 2,272,747
Rv2026c
Rv2027c: Rv2027c - Two component sensor histidine kinase DosT, at 2,272,787 to 2,274,508
Rv2027c
Rv2028c: Rv2028c - Universal stress protein family protein, at 2,274,569 to 2,275,408
Rv2028c
Group
Condition
Rv2024c
Rv2025c
Rv2026c
Rv2027c
Rv2028c
stress
7H9 with Isoniazid 0.025 ug/mL
-0.2
-0.4
-1.6
-0.2
-1.1
no stress control
no stress control
-0.1
+0.1
-1.2
-0.0
-1.3
stress
7H9 with Isoniazid 0.025 ug/mL
-0.1
+0.5
-1.9
-0.3
-0.5
stress
7H9 with Clofazimine 0.072 ug/mL
-0.1
+0.1
-0.2
+0.1
-1.4
stress
7H9 with Ethambutol 0.75 ug/mL
-0.0
+0.4
-0.2
+0.1
-1.4
stress
7H9 with Delamanid 0.236 ug/mL
+0.1
-0.5
+0.3
-0.2
-0.7
stress
7H9 with Ofloxacin 0.8 ug/mL
-0.5
+0.7
-0.1
+0.1
-0.5
carbon source
Palmitic 100 uM (C)
+0.0
-0.2
+0.5
+0.3
-0.8
no stress control
no stress control
-0.1
+1.0
-0.5
-0.4
+0.5
stress
7H9 with Ofloxacin 0.8 ug/mL
-0.2
+0.1
-0.5
-0.1
+1.6
carbon source
Valeric 10 mM (C)
-0.1
-0.4
+0.3
+0.0
+0.9
stress
7H9 with Levofloxacin 0.3 ug/mL
-0.3
+1.0
+0.1
-0.1
+0.1
stress
7H9 with Sulfamethizole 0.026 mM
-0.1
-0.2
+0.8
+0.1
+0.5
carbon source
Stearic 100 uM (C)
+0.1
-0.3
+0.1
+0.1
+1.2
nitrogen source
L-Serine 10 mM (N)
+0.1
+0.0
+1.4
-0.1
-0.2
carbon source
D-Lactate 10 mM (C)
-0.2
-0.1
+0.8
+0.1
+0.6
stress
7H9 with Ethionamide 0.1 ug/mL
-0.2
-0.2
+1.1
+0.0
+0.5
nitrogen source
L-Asparagine 10 mM (N)
-0.1
+0.5
+1.2
-0.0
-0.4
nitrogen source
L-Serine 10 mM (N)
+0.1
-0.1
+0.9
-0.0
+0.5
carbon source
D-Lactate 10 mM (C)
-0.1
+0.2
+0.9
+0.2
+0.4
carbon source
L-Glutamine (C)
+0.1
-0.1
+1.0
+0.2
+0.6
nitrogen source
L-Alanine 10 mM (N)
+0.0
+0.1
+1.3
-0.3
+0.7
nitrogen source
L-Glutamine 10 mM (N)
+0.0
+0.4
+0.7
-0.2
+0.8
stress
7H9 with Clofazimine 0.072 ug/mL
+0.0
+0.5
+0.7
+0.1
+0.6
nitrogen source
L-Alanine 10 mM (N)
+0.0
+0.4
+1.1
-0.1
+0.7
nitrogen source
Glycine 10 mM (N)
+0.1
+0.2
+1.3
-0.1
+0.5
stress
7H9 with Moxifloxacin 0.121 ug/mL
-0.4
+0.8
-0.1
-0.1
+1.9
nitrogen source
L-Glutamic 10 mM (N)
-0.2
-0.2
+1.0
-0.5
+2.0
nitrogen source
L-Glutamic 10 mM (N)
+0.2
+0.4
+1.2
-0.1
+0.5
nitrogen source
L-Valine 10 mM (N)
+0.3
+0.4
+1.7
+0.1
-0.0
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