Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv2021c and Rv2022c are separated by 8 nucleotidesRv2022c and Rv2023c are separated by 24 nucleotidesRv2023c and Rv2023A are separated by 159 nucleotidesRv2023A and Rv2024c overlap by 34 nucleotides Rv2021c: Rv2021c - Transcriptional regulatory protein, at 2,266,805 to 2,267,110 Rv2021c Rv2022c: Rv2022c - Conserved protein, at 2,267,119 to 2,267,724 Rv2022c Rv2023c: Rv2023c - Hypothetical protein, at 2,267,749 to 2,268,108 Rv2023c Rv2023A: Rv2023A - Hypothetical protein, pseudogene, at 2,268,268 to 2,268,726 Rv2023A Rv2024c: Rv2024c - Conserved hypothetical protein, at 2,268,693 to 2,270,240 Rv2024c
Group Condition Rv2021c Rv2022c Rv2023c Rv2023A Rv2024c
carbon source cholesterol 100uM (C) -0.9 -0.2 -0.4 -0.2 +0.1
stress 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM -0.4 -0.4 -0.3 +0.1 -0.4
stress 7H9 with Sutezolid 0.12 ug/mL -0.9 -0.0 -0.4 +0.0 -0.1
pH pH 5.5 -1.0 -0.0 +0.3 -0.4 -0.2
stress 7H9 with Chlorpromazine 0.054 mM -0.8 +0.2 -0.3 -0.4 +0.0
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 -0.4 -0.0 +0.1 -0.5 -0.4
pH pH 4.5 -0.8 -0.1 +0.6 -0.7 +0.0
stress 7H9 with Dodecyl Sulfate 0.02 vol% -1.1 +0.1 -0.1 +0.4 -0.2
stress 7H9 with nitrite 1.5 mM; pH 5.5 -0.5 +0.0 +0.4 -0.5 -0.2
stress 7H9 with Dicloxacillin 0.0069 mM +0.5 -0.1 -0.3 -0.6 -0.3
pH pH 4.5 -1.2 +0.0 +0.3 -0.1 +0.2
stress 7H9 with Ciprofloxacin Hydrochloride 0.001 mM -0.3 +0.1 +0.4 -0.7 -0.0
stress 7H9 with Ramoplanin 0.009 mM -0.4 -0.5 +0.5 -0.0 +0.2
no stress control no stress control -0.3 -0.3 +0.8 -0.4 -0.0
nitrogen source L-Valine 10 mM (N) -0.2 +0.6 -0.4 -0.1 +0.1
stress 7H9 with nitrate 4 mM +0.6 -0.1 -0.5 +0.3 -0.3
stress 7H9 with Sisomicin 0.07 mM +0.4 -0.1 -0.6 +0.2 +0.2
stress 7H9 with Nickel (II) chloride 0.6 mM -0.0 +0.3 +0.4 -0.4 -0.2
stress 7H9 with 2,4-Dinitrophenol 0.1503 mM +0.6 -0.1 -0.3 +0.3 -0.3
stress 7H9 with Norfloxacin 0.125 mM +0.8 +0.3 -0.0 -0.2 -0.3
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -0.0 +0.2 +0.9 -0.5 -0.0
nitrogen source L-Glutamic 10 mM (N) +0.6 +0.2 -0.2 -0.2 +0.2
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -0.1 -0.2 -0.1 +1.1 -0.1
no stress control no stress control +0.4 +0.2 +0.2 +0.3 -0.3
stress 7H9 with Isoniazid 0.025 ug/mL +0.8 -0.2 +0.1 +0.5 -0.2
no stress control no stress control +0.9 -0.4 +0.2 +0.5 -0.2
stress 7H9 with Pretomanid 0.213 ug/mL +1.4 +0.1 -0.4 +0.2 -0.2
stress 7H9 with nitrite 2.5 mM +0.6 +0.5 +0.2 +0.0 -0.1
no stress control no stress control +0.9 +0.2 -0.2 +0.1 +0.2
stress 7H9 with Nickel (II) chloride 0.6 mM +0.4 +0.3 +0.4 -0.0 +0.2
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