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Protein
Homologs
Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv2021c and Rv2022c are separated by 8 nucleotides
Rv2022c and Rv2023c are separated by 24 nucleotides
Rv2023c and Rv2023A are separated by 159 nucleotides
Rv2023A and Rv2024c overlap by 34 nucleotides
Rv2021c: Rv2021c - Transcriptional regulatory protein, at 2,266,805 to 2,267,110
Rv2021c
Rv2022c: Rv2022c - Conserved protein, at 2,267,119 to 2,267,724
Rv2022c
Rv2023c: Rv2023c - Hypothetical protein, at 2,267,749 to 2,268,108
Rv2023c
Rv2023A: Rv2023A - Hypothetical protein, pseudogene, at 2,268,268 to 2,268,726
Rv2023A
Rv2024c: Rv2024c - Conserved hypothetical protein, at 2,268,693 to 2,270,240
Rv2024c
Group
Condition
Rv2021c
Rv2022c
Rv2023c
Rv2023A
Rv2024c
carbon source
cholesterol 100uM (C)
-0.9
-0.2
-0.4
-0.2
+0.1
stress
7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM
-0.4
-0.4
-0.3
+0.1
-0.4
stress
7H9 with Sutezolid 0.12 ug/mL
-0.9
-0.0
-0.4
+0.0
-0.1
pH
pH 5.5
-1.0
-0.0
+0.3
-0.4
-0.2
stress
7H9 with Chlorpromazine 0.054 mM
-0.8
+0.2
-0.3
-0.4
+0.0
stress
7H9 with Hydrogen peroxide 2.5 mM; pH 6.5
-0.4
-0.0
+0.1
-0.5
-0.4
pH
pH 4.5
-0.8
-0.1
+0.6
-0.7
+0.0
stress
7H9 with Dodecyl Sulfate 0.02 vol%
-1.1
+0.1
-0.1
+0.4
-0.2
stress
7H9 with nitrite 1.5 mM; pH 5.5
-0.5
+0.0
+0.4
-0.5
-0.2
stress
7H9 with Dicloxacillin 0.0069 mM
+0.5
-0.1
-0.3
-0.6
-0.3
pH
pH 4.5
-1.2
+0.0
+0.3
-0.1
+0.2
stress
7H9 with Ciprofloxacin Hydrochloride 0.001 mM
-0.3
+0.1
+0.4
-0.7
-0.0
stress
7H9 with Ramoplanin 0.009 mM
-0.4
-0.5
+0.5
-0.0
+0.2
no stress control
no stress control
-0.3
-0.3
+0.8
-0.4
-0.0
nitrogen source
L-Valine 10 mM (N)
-0.2
+0.6
-0.4
-0.1
+0.1
stress
7H9 with nitrate 4 mM
+0.6
-0.1
-0.5
+0.3
-0.3
stress
7H9 with Sisomicin 0.07 mM
+0.4
-0.1
-0.6
+0.2
+0.2
stress
7H9 with Nickel (II) chloride 0.6 mM
-0.0
+0.3
+0.4
-0.4
-0.2
stress
7H9 with 2,4-Dinitrophenol 0.1503 mM
+0.6
-0.1
-0.3
+0.3
-0.3
stress
7H9 with Norfloxacin 0.125 mM
+0.8
+0.3
-0.0
-0.2
-0.3
stress
7H9 with Hydrogen peroxide 2.5 mM; pH 5.5
-0.0
+0.2
+0.9
-0.5
-0.0
nitrogen source
L-Glutamic 10 mM (N)
+0.6
+0.2
-0.2
-0.2
+0.2
stress
7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM
-0.1
-0.2
-0.1
+1.1
-0.1
no stress control
no stress control
+0.4
+0.2
+0.2
+0.3
-0.3
stress
7H9 with Isoniazid 0.025 ug/mL
+0.8
-0.2
+0.1
+0.5
-0.2
no stress control
no stress control
+0.9
-0.4
+0.2
+0.5
-0.2
stress
7H9 with Pretomanid 0.213 ug/mL
+1.4
+0.1
-0.4
+0.2
-0.2
stress
7H9 with nitrite 2.5 mM
+0.6
+0.5
+0.2
+0.0
-0.1
no stress control
no stress control
+0.9
+0.2
-0.2
+0.1
+0.2
stress
7H9 with Nickel (II) chloride 0.6 mM
+0.4
+0.3
+0.4
-0.0
+0.2
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