Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv1925 and Rv1926c are separated by 7 nucleotidesRv1926c and Rv1927 are separated by 236 nucleotidesRv1927 and Rv1928c are separated by 3 nucleotidesRv1928c and Rv1929c are separated by 44 nucleotides Rv1925: Rv1925 - Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase), at 2,177,087 to 2,178,949 Rv1925 Rv1926c: Rv1926c - Immunogenic protein Mpt63 (antigen Mpt63/MPB63) (16 kDa immunoprotective extracellular protein), at 2,178,957 to 2,179,436 Rv1926c Rv1927: Rv1927 - Conserved hypothetical protein, at 2,179,673 to 2,180,446 Rv1927 Rv1928c: Rv1928c - Probable short-chain type dehydrogenase/reductase, at 2,180,450 to 2,181,217 Rv1928c Rv1929c: Rv1929c - Conserved hypothetical protein, at 2,181,262 to 2,181,906 Rv1929c
Group Condition Rv1925 Rv1926c Rv1927 Rv1928c Rv1929c
stress 7H9 with copper (II) chloride 0.08 mM -0.8 -0.4 -0.6 -1.0 -0.9
stress 7H9 with Hydrogen peroxide 3.97 mM -1.5 -0.9 +0.2 -0.4 +0.1
stress 7H9 with copper (II) chloride 0.08 mM -0.6 -0.3 -0.5 -0.3 -0.5
stress 7H9 with methylglyoxal 1.2 mM -0.7 -1.2 -0.1 -0.3 +0.3
stress 7H9 with Rifampicin 0.014 ug/mL -0.7 -1.0 -0.2 -0.0 +0.1
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 -1.6 -0.9 -0.0 +1.0 -0.0
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.2 -0.8 -0.1 +0.2 -1.0
stress 7H9 with Plumbagin 0.01 mM -0.7 -0.5 +0.1 -0.6 +0.5
no stress control no stress control +0.1 -1.2 -0.1 +0.5 -0.3
stress 7H9 with methylglyoxal 1.2 mM -0.8 +0.2 -0.2 -0.6 +0.3
nitrogen source Ammonium chloride 10mM (N) -0.2 -1.1 +0.0 -0.3 +0.5
nitrogen source L-Alanine 10 mM (N) -0.2 -1.3 +0.4 -0.1 +0.4
stress 7H9 with Cumene hydroperoxide 0.05 mM -2.0 +0.1 +0.1 +0.3 +0.6
stress 7H9 with Linezolid 0.3 ug/mL -0.5 -0.5 +0.2 -0.6 +0.6
stress 7H9 with Isoniazid 0.025 ug/mL +0.9 -1.0 +0.0 -0.6 +0.2
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM -0.7 -0.4 -0.2 -0.2 +0.9
stress 7H9 with Chloramphenicol 0.01 mM -0.6 -1.1 +0.0 +0.7 +0.5
stress 7H9 with Hydrogen peroxide 3.97 mM -1.5 +0.3 +0.2 +0.1 +0.5
stress 7H9 with Sisomicin 0.07 mM +0.2 +0.5 -0.4 +0.4 -0.9
stress 7H9 with Cumene hydroperoxide 0.05 mM -1.9 +0.5 +0.1 +0.4 +0.7
carbon source oleate 200uM (C) -0.7 -0.6 +0.1 +0.8 +0.4
stress 7H9 with Phenazine ethosulfate 0.0137 mM -0.8 -0.2 -0.1 +0.6 +0.5
stress 7H9 with Erythromycin 0.016 mM -0.3 +1.2 +0.0 -0.2 -0.5
stress 7H9 with Ethionamide 0.1 ug/mL +0.6 -1.1 +0.1 +0.6 -0.1
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 -1.4 +1.4 +0.1 +0.7 -0.1
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -0.6 +0.4 +0.4 +1.0 -0.2
stress 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM -0.5 +0.8 +0.2 +0.4 +0.3
stress 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM -0.4 +0.6 -0.1 -0.0 +1.1
pH 7H9 pH 5.5 -0.1 +1.0 +0.4 -0.1 +0.6
stress 7H9 with Ciprofloxacin Hydrochloride 0.001 mM -0.3 +0.8 +0.4 +0.9 -0.0
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