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Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Number of genes on each side:
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv1925 and Rv1926c are separated by 7 nucleotides
Rv1926c and Rv1927 are separated by 236 nucleotides
Rv1927 and Rv1928c are separated by 3 nucleotides
Rv1928c and Rv1929c are separated by 44 nucleotides
Rv1925: Rv1925 - Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase), at 2,177,087 to 2,178,949
Rv1925
Rv1926c: Rv1926c - Immunogenic protein Mpt63 (antigen Mpt63/MPB63) (16 kDa immunoprotective extracellular protein), at 2,178,957 to 2,179,436
Rv1926c
Rv1927: Rv1927 - Conserved hypothetical protein, at 2,179,673 to 2,180,446
Rv1927
Rv1928c: Rv1928c - Probable short-chain type dehydrogenase/reductase, at 2,180,450 to 2,181,217
Rv1928c
Rv1929c: Rv1929c - Conserved hypothetical protein, at 2,181,262 to 2,181,906
Rv1929c
Group
Condition
Rv1925
Rv1926c
Rv1927
Rv1928c
Rv1929c
stress
7H9 with copper (II) chloride 0.08 mM
-0.8
-0.4
-0.6
-1.0
-0.9
stress
7H9 with Hydrogen peroxide 3.97 mM
-1.5
-0.9
+0.2
-0.4
+0.1
stress
7H9 with copper (II) chloride 0.08 mM
-0.6
-0.3
-0.5
-0.3
-0.5
stress
7H9 with methylglyoxal 1.2 mM
-0.7
-1.2
-0.1
-0.3
+0.3
stress
7H9 with Rifampicin 0.014 ug/mL
-0.7
-1.0
-0.2
-0.0
+0.1
stress
7H9 with Hydrogen peroxide 2.5 mM; pH 6.5
-1.6
-0.9
-0.0
+1.0
-0.0
stress
7H9 with Moxifloxacin 0.121 ug/mL
+0.2
-0.8
-0.1
+0.2
-1.0
stress
7H9 with Plumbagin 0.01 mM
-0.7
-0.5
+0.1
-0.6
+0.5
no stress control
no stress control
+0.1
-1.2
-0.1
+0.5
-0.3
stress
7H9 with methylglyoxal 1.2 mM
-0.8
+0.2
-0.2
-0.6
+0.3
nitrogen source
Ammonium chloride 10mM (N)
-0.2
-1.1
+0.0
-0.3
+0.5
nitrogen source
L-Alanine 10 mM (N)
-0.2
-1.3
+0.4
-0.1
+0.4
stress
7H9 with Cumene hydroperoxide 0.05 mM
-2.0
+0.1
+0.1
+0.3
+0.6
stress
7H9 with Linezolid 0.3 ug/mL
-0.5
-0.5
+0.2
-0.6
+0.6
stress
7H9 with Isoniazid 0.025 ug/mL
+0.9
-1.0
+0.0
-0.6
+0.2
stress
7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM
-0.7
-0.4
-0.2
-0.2
+0.9
stress
7H9 with Chloramphenicol 0.01 mM
-0.6
-1.1
+0.0
+0.7
+0.5
stress
7H9 with Hydrogen peroxide 3.97 mM
-1.5
+0.3
+0.2
+0.1
+0.5
stress
7H9 with Sisomicin 0.07 mM
+0.2
+0.5
-0.4
+0.4
-0.9
stress
7H9 with Cumene hydroperoxide 0.05 mM
-1.9
+0.5
+0.1
+0.4
+0.7
carbon source
oleate 200uM (C)
-0.7
-0.6
+0.1
+0.8
+0.4
stress
7H9 with Phenazine ethosulfate 0.0137 mM
-0.8
-0.2
-0.1
+0.6
+0.5
stress
7H9 with Erythromycin 0.016 mM
-0.3
+1.2
+0.0
-0.2
-0.5
stress
7H9 with Ethionamide 0.1 ug/mL
+0.6
-1.1
+0.1
+0.6
-0.1
stress
7H9 with Hydrogen peroxide 2.5 mM; pH 6.5
-1.4
+1.4
+0.1
+0.7
-0.1
stress
7H9 with Hydrogen peroxide 2.5 mM; pH 5.5
-0.6
+0.4
+0.4
+1.0
-0.2
stress
7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM
-0.5
+0.8
+0.2
+0.4
+0.3
stress
7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM
-0.4
+0.6
-0.1
-0.0
+1.1
pH
7H9 pH 5.5
-0.1
+1.0
+0.4
-0.1
+0.6
stress
7H9 with Ciprofloxacin Hydrochloride 0.001 mM
-0.3
+0.8
+0.4
+0.9
-0.0
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