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Protein
Homologs
Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv1900c and Rv1901 are separated by 28 nucleotides
Rv1901 and Rv1902c are separated by 51 nucleotides
Rv1902c and Rv1903 are separated by 89 nucleotides
Rv1903 and Rv1904 are separated by 185 nucleotides
Rv1900c: Rv1900c - Probable lignin peroxidase LipJ, at 2,146,245 to 2,147,633
Rv1900c
Rv1901: Rv1901 - Probable CinA-like protein CinA, at 2,147,662 to 2,148,954
Rv1901
Rv1902c: Rv1902c - Probable sialic acid-transport integral membrane protein NanT, at 2,149,006 to 2,150,274
Rv1902c
Rv1903: Rv1903 - Probable conserved membrane protein, at 2,150,364 to 2,150,768
Rv1903
Rv1904: Rv1904 - Conserved hypothetical protein, at 2,150,954 to 2,151,385
Rv1904
Group
Condition
Rv1900c
Rv1901
Rv1902c
Rv1903
Rv1904
stress
7H9 with Pretomanid 0.213 ug/mL
-0.4
-1.3
+0.0
-0.3
-0.3
stress
7H9 with Ethionamide 0.1 ug/mL
+0.2
-1.7
-0.3
-0.2
+0.2
stress
7H9 with Isoniazid 0.025 ug/mL
+0.2
-1.4
-0.0
-0.2
-0.2
stress
7H9 with Ethionamide 0.1 ug/mL
-0.4
-1.4
+0.0
+0.1
+0.2
stress
7H9 with Isoniazid 0.025 ug/mL
+0.3
-1.4
-0.1
+0.1
-0.3
stress
7H9 with Pretomanid 0.213 ug/mL
+0.1
-1.2
-0.0
+0.0
-0.2
stress
7H9 with Delamanid 0.236 ug/mL
-0.1
-0.8
+0.0
-0.1
-0.2
stress
7H9 with Hygromycin B 0.0095 mM
-0.2
-0.2
-0.1
-0.3
-0.2
stress
7H9 with para-aminosalicylic 0.086 ug/mL
-0.5
-0.1
-0.1
-0.2
-0.1
stress
7H9 with Delamanid 0.236 ug/mL
-0.0
-0.7
-0.0
+0.1
+0.1
nitrogen source
L-Valine 10 mM (N)
+0.3
-0.2
-0.2
-0.3
-0.2
stress
7H9 with Dimethyl Sulfoxide 1 vol%
-0.2
+0.2
-0.1
-0.2
-0.2
no stress control
no stress control
-0.3
+0.2
-0.0
-0.3
+0.1
carbon source
D,L-Malic Acid 10 mM (C)
-0.5
-0.1
-0.0
+0.3
-0.1
stress
7H9 with Bedaquiline 0.15 ug/mL
+0.2
+0.1
+0.1
-0.2
-0.3
carbon source
D-Glucose (C)
-0.3
+0.2
+0.0
+0.1
-0.1
stress
7H9 with Sulfamethizole 0.026 mM
-0.2
+0.6
-0.1
-0.2
-0.1
carbon source
L-Aspartic Acid (C)
-0.3
+0.1
+0.0
+0.4
-0.1
carbon source
propionate (C)
+0.0
+0.3
-0.0
+0.3
-0.3
stress
7H9 with Sulfamethizole 0.026 mM
-0.1
+0.6
+0.1
-0.4
+0.0
stress
7H9 with Bedaquiline 0.15 ug/mL
+0.3
+0.2
+0.1
-0.2
+0.0
stress
7H9 with Moxifloxacin 0.121 ug/mL
+0.3
+0.5
-0.0
+0.1
-0.1
stress
7H9 with Ethambutol 0.75 ug/mL
+0.2
+0.2
+0.2
+0.2
-0.1
stress
7H9 with Ofloxacin 0.8 ug/mL
+0.4
+0.2
-0.0
+0.2
+0.1
stress
7H9 with Levofloxacin 0.3 ug/mL
+0.2
+0.1
-0.0
+0.5
+0.1
carbon source
Palmitic 100 uM (C)
+0.4
+0.2
+0.0
+0.3
+0.0
stress
7H9 with Clofazimine 0.072 ug/mL
+0.2
+0.2
+0.2
+0.3
+0.1
stress
7H9 with Moxifloxacin 0.121 ug/mL
+0.6
+0.2
-0.2
+0.3
+0.1
no stress control
no stress control
+0.7
+0.2
-0.2
+0.3
+0.2
stress
7H9 with Ofloxacin 0.8 ug/mL
+0.5
+0.4
+0.0
+0.2
+0.1
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