Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv1872c and Rv1873 are separated by 22 nucleotidesRv1873 and Rv1874 are separated by 72 nucleotidesRv1874 and Rv1875 are separated by 10 nucleotidesRv1875 and Rv1876 are separated by 515 nucleotides Rv1872c: Rv1872c - Possible L-lactate dehydrogenase (cytochrome) LldD2, at 2,121,907 to 2,123,151 Rv1872c Rv1873: Rv1873 - Conserved hypothetical protein, at 2,123,174 to 2,123,611 Rv1873 Rv1874: Rv1874 - Unknown protein, at 2,123,684 to 2,124,370 Rv1874 Rv1875: Rv1875 - Conserved protein, at 2,124,381 to 2,124,824 Rv1875 Rv1876: Rv1876 - Probable bacterioferritin BfrA, at 2,125,340 to 2,125,819 Rv1876
Group Condition Rv1872c Rv1873 Rv1874 Rv1875 Rv1876
carbon source L-Lactate 10 mM (C) -2.5 -0.0 -0.1 -0.4 +0.1
carbon source L-Lactate 10 mM (C) -2.4 -0.0 -0.2 -0.1 -0.1
no stress control no stress control +0.3 -0.1 -0.4 -1.1 -0.2
no stress control no stress control -0.3 -0.4 +0.2 -0.5 -0.1
no stress control no stress control +0.1 -0.2 -0.1 -0.7 -0.2
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 -0.2 +0.0 +0.0 -1.1 +0.1
stress 7H9 with Cumene hydroperoxide 0.05 mM +0.1 -0.1 -0.2 -0.3 -0.3
stress 7H9 with Pretomanid 0.213 ug/mL +0.0 +0.1 -0.2 -0.7 -0.1
stress 7H9 with Doxycycline hyclate 0.0035 mM +0.3 +0.2 -0.3 -0.5 -0.2
stress 7H9 with Phenazine methosulfate 0.0054 mM +0.2 +0.2 -0.2 -0.7 +0.1
stress 7H9 with Levofloxacin 0.3 ug/mL +0.4 +0.1 -0.1 -0.4 -0.3
stress 7H9 with Isoniazid 0.025 ug/mL +0.4 +0.2 +0.2 -0.7 -0.4
stress 7H9 with Ofloxacin 0.8 ug/mL +0.5 +0.1 +0.1 -0.6 -0.4
stress 7H9 with Dibucaine 0.21 mM +0.5 -0.0 -0.2 -0.5 +0.2
no stress control no stress control +0.3 +0.1 +0.1 -0.5 -0.1
stress 7H9 with Formaldehyde 0.23 mM +0.4 +0.0 +0.1 -0.3 -0.2
stress 7H9 with Ethionamide 0.1 ug/mL +0.3 +0.2 +0.0 -0.4 -0.2
stress 7H9 with Spectinomycin 0.029 mM -0.0 -0.3 -0.0 +0.6 -0.2
stress 7H9 with copper (II) chloride 0.08 mM +0.1 -0.1 -0.4 +0.5 -0.0
no stress control no stress control -0.2 -0.1 -0.1 +0.6 -0.1
stress 7H9 with Ofloxacin 0.8 ug/mL +0.3 +0.2 +0.2 -0.5 +0.0
stress 7H9 with Isoniazid 0.025 ug/mL +0.6 +0.2 -0.1 -0.4 -0.0
stress 7H9 with Sutezolid 0.12 ug/mL +0.2 +0.2 +0.2 -0.4 +0.2
stress 7H9 with Novobiocin 0.004 mM +0.4 +0.0 -0.1 +0.5 -0.2
stress 7H9 with copper (II) chloride 0.08 mM +0.2 +0.1 -0.2 +0.4 +0.3
no stress control no stress control +0.0 -0.0 -0.1 +0.9 -0.1
stress 7H9 with Ciprofloxacin Hydrochloride 0.001 mM +0.4 -0.1 +0.0 +0.4 +0.2
stress 7H9 with Tetrazolium violet 0.065 mM +0.3 +0.1 -0.2 +0.3 +0.4
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM +0.3 +0.2 -0.1 +0.4 +0.1
stress 7H9 with Novobiocin 0.004 mM +0.2 +0.4 +0.1 +0.0 +0.2
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