Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv1869c and Rv1870c are separated by 99 nucleotidesRv1870c and Rv1871c are separated by 64 nucleotidesRv1871c and Rv1872c are separated by 22 nucleotidesRv1872c and Rv1873 are separated by 22 nucleotides Rv1869c: Rv1869c - Probable reductase, at 2,119,460 to 2,120,695 Rv1869c Rv1870c: Rv1870c - Conserved hypothetical protein, at 2,120,795 to 2,121,430 Rv1870c Rv1871c: Rv1871c - Conserved protein, at 2,121,495 to 2,121,884 Rv1871c Rv1872c: Rv1872c - Possible L-lactate dehydrogenase (cytochrome) LldD2, at 2,121,907 to 2,123,151 Rv1872c Rv1873: Rv1873 - Conserved hypothetical protein, at 2,123,174 to 2,123,611 Rv1873
Group Condition Rv1869c Rv1870c Rv1871c Rv1872c Rv1873
carbon source L-Lactate 10 mM (C) -0.1 +0.1 -0.0 -2.4 -0.0
carbon source L-Lactate 10 mM (C) +0.1 +0.1 -0.0 -2.5 -0.0
carbon source D,L-Malic Acid 10 mM (C) +0.3 -0.2 -0.1 -0.2 -0.1
carbon source Valeric 10 mM (C) -0.2 -0.1 +0.2 -0.4 +0.1
stress 7H9 with Isoniazid 0.025 ug/mL -0.5 -0.1 -0.3 +0.4 +0.2
stress 7H9 with Ethionamide 0.1 ug/mL -0.9 +0.2 +0.2 +0.1 +0.2
nitrogen source L-Serine 10 mM (N) +0.3 +0.0 -0.2 +0.2 -0.3
no stress control no stress control -0.3 +0.2 -0.1 +0.3 +0.1
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.4 +0.1 +0.2 +0.2 +0.2
stress 7H9 with Ethionamide 0.1 ug/mL -0.3 +0.1 +0.0 +0.3 +0.2
carbon source Stearic 100 uM (C) +0.0 +0.1 +0.5 -0.2 -0.0
stress 7H9 with Bedaquiline 0.15 ug/mL +0.3 -0.1 +0.2 +0.2 -0.1
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.2 +0.2 -0.1 +0.2 +0.2
stress 7H9 with Ofloxacin 0.8 ug/mL -0.4 +0.3 +0.2 +0.3 +0.1
stress 7H9 with Levofloxacin 0.3 ug/mL -0.2 +0.2 +0.2 +0.4 +0.1
stress 7H9 with Ofloxacin 0.8 ug/mL -0.2 +0.1 +0.0 +0.5 +0.1
nitrogen source L-Asparagine 10 mM (N) +0.2 +0.2 -0.2 +0.4 +0.0
stress 7H9 with Hygromycin B 0.0095 mM +0.0 +0.3 +0.4 -0.1 +0.1
stress 7H9 with Isoniazid 0.025 ug/mL -0.4 +0.1 +0.3 +0.6 +0.2
carbon source Glycerol (C) -0.2 +0.3 +0.3 +0.2 +0.1
nitrogen source L-Aspartic Acid 10 mM (N) +0.3 +0.2 +0.1 +0.2 -0.0
stress 7H9 with para-aminosalicylic 0.086 ug/mL +0.1 +0.0 +0.6 +0.1 +0.1
stress 7H9 with Meropenem 9.6 ug/mL +0.2 +0.3 +0.2 +0.1 -0.0
no stress control no stress control +0.4 +0.2 +0.1 +0.0 +0.1
stress 7H9 with para-aminosalicylic 0.086 ug/mL -0.1 -0.0 +0.6 +0.1 +0.2
carbon source D-Glucose (C) +0.1 +0.2 +0.4 +0.0 +0.1
stress 7H9 with Hygromycin B 0.0095 mM +0.4 +0.1 +0.0 +0.2 +0.1
no stress control no stress control +0.4 +0.2 -0.1 +0.2 +0.1
stress 7H9 with Streptomycin 0.178 ug/mL -0.0 +0.2 +0.5 +0.2 +0.1
stress 7H9 with Dimethyl Sulfoxide 1 vol% +0.6 +0.1 +0.6 +0.2 +0.2
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