Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv1867 and Rv1868 are separated by 98 nucleotidesRv1868 and Rv1869c are separated by 13 nucleotidesRv1869c and Rv1870c are separated by 99 nucleotidesRv1870c and Rv1871c are separated by 64 nucleotides Rv1867: Rv1867 - Conserved protein, at 2,115,764 to 2,117,248 Rv1867 Rv1868: Rv1868 - Conserved hypothetical protein, at 2,117,347 to 2,119,446 Rv1868 Rv1869c: Rv1869c - Probable reductase, at 2,119,460 to 2,120,695 Rv1869c Rv1870c: Rv1870c - Conserved hypothetical protein, at 2,120,795 to 2,121,430 Rv1870c Rv1871c: Rv1871c - Conserved protein, at 2,121,495 to 2,121,884 Rv1871c
Group Condition Rv1867 Rv1868 Rv1869c Rv1870c Rv1871c
stress 7H9 with Isoniazid 0.025 ug/mL -0.4 -0.3 -0.5 -0.1 -0.3
stress 7H9 with Ethionamide 0.1 ug/mL -0.2 -0.0 -0.9 +0.2 +0.2
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.0 -0.4 -0.2 +0.2 -0.1
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.1 -0.3 -0.4 +0.1 +0.2
carbon source D,L-Malic Acid 10 mM (C) -0.1 -0.1 +0.3 -0.2 -0.1
no stress control no stress control -0.2 -0.2 -0.1 +0.2 +0.0
stress 7H9 with Ofloxacin 0.8 ug/mL +0.0 -0.3 -0.4 +0.3 +0.2
stress 7H9 with Levofloxacin 0.3 ug/mL -0.2 -0.2 -0.2 +0.2 +0.2
stress 7H9 with Isoniazid 0.025 ug/mL -0.0 -0.1 -0.4 +0.1 +0.3
nitrogen source L-Asparagine 10 mM (N) -0.2 -0.3 +0.1 +0.2 +0.1
no stress control no stress control +0.2 -0.1 -0.3 +0.2 -0.1
stress 7H9 with Rifampicin 0.014 ug/mL +0.2 -0.3 +0.0 +0.2 -0.2
stress 7H9 with Bedaquiline 0.15 ug/mL -0.1 -0.0 +0.3 -0.1 +0.2
stress 7H9 with Dimethyl Sulfoxide 1 vol% -0.3 +0.0 +0.1 +0.2 +0.2
carbon source D-Trehalose 10 mM (C) +0.2 -0.2 +0.2 -0.1 +0.1
stress 7H9 with Clofazimine 0.45 ug/mL -0.1 +0.3 -0.0 +0.3 -0.1
carbon source Valeric 10 mM (C) +0.2 +0.2 -0.2 -0.1 +0.2
stress 7H9 with para-aminosalicylic 0.086 ug/mL -0.0 -0.1 -0.1 -0.0 +0.6
no stress control no stress control -0.1 -0.2 +0.4 +0.2 +0.1
stress 7H9 with Rifampicin 0.014 ug/mL +0.3 -0.2 +0.1 +0.1 +0.1
stress 7H9 with Hygromycin B 0.0095 mM -0.2 -0.1 +0.0 +0.3 +0.4
nitrogen source L-Asparagine 10 mM (N) +0.2 -0.0 +0.2 +0.2 -0.2
no stress control no stress control +0.0 -0.1 +0.4 +0.2 -0.1
carbon source Glycerol (C) +0.1 +0.0 -0.2 +0.3 +0.3
carbon source D-Glucose (C) +0.1 +0.1 -0.1 +0.2 +0.3
stress 7H9 with Rifampicin 0.00045 ug/mL +0.2 +0.1 +0.1 +0.1 -0.1
carbon source D-Glucose (C) -0.1 +0.1 +0.1 +0.2 +0.4
stress 7H9 with Streptomycin 0.178 ug/mL +0.2 -0.2 -0.0 +0.2 +0.5
stress 7H9 with Meropenem 9.6 ug/mL +0.1 -0.0 +0.2 +0.3 +0.2
stress 7H9 with Dimethyl Sulfoxide 1 vol% -0.0 +0.0 +0.6 +0.1 +0.6
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