Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv1830 and Rv1831 are separated by 52 nucleotidesRv1831 and Rv1832 are separated by 48 nucleotidesRv1832 and Rv1833c are separated by 226 nucleotidesRv1833c and Rv1834 are separated by 40 nucleotides Rv1830: Rv1830 - Conserved hypothetical protein, at 2,074,841 to 2,075,518 Rv1830 Rv1831: Rv1831 - Hypothetical protein, at 2,075,571 to 2,075,828 Rv1831 Rv1832: Rv1832 - Probable glycine dehydrogenase GcvB (glycine decarboxylase) (glycine cleavage system P-protein), at 2,075,877 to 2,078,702 Rv1832 Rv1833c: Rv1833c - Possible haloalkane dehalogenase, at 2,078,929 to 2,079,789 Rv1833c Rv1834: Rv1834 - Probable hydrolase, at 2,079,830 to 2,080,696 Rv1834
Group Condition Rv1830 Rv1831 Rv1832 Rv1833c Rv1834
no stress control no stress control N.D. -0.4 N.D. -0.5 -0.3
stress 7H9 with Levofloxacin 0.3 ug/mL N.D. -0.8 N.D. -0.1 -0.3
stress 7H9 with Moxifloxacin 0.121 ug/mL N.D. -0.3 N.D. -0.2 -0.7
stress 7H9 with Ethionamide 0.1 ug/mL N.D. -0.3 N.D. -0.5 -0.3
nitrogen source L-Valine 10 mM (N) N.D. -0.3 N.D. -0.5 -0.2
carbon source L-Lactate 10 mM (C) N.D. -0.0 N.D. -0.2 -0.6
carbon source heptadecanoic 250 uM (C) N.D. -0.4 N.D. -0.0 -0.3
stress 7H9 with Ethionamide 0.1 ug/mL N.D. -0.2 N.D. -0.1 -0.4
stress 7H9 with Ofloxacin 0.8 ug/mL N.D. -0.2 N.D. -0.2 -0.3
nitrogen source L-Glutamine 10 mM (N) N.D. -0.5 N.D. -0.2 -0.0
carbon source heptadecanoic 250 uM (C) N.D. -0.3 N.D. -0.3 -0.1
stress 7H9 with para-aminosalicylic 0.086 ug/mL N.D. +0.0 N.D. -0.4 -0.2
stress 7H9 with Streptomycin 0.178 ug/mL N.D. +0.1 N.D. -0.3 -0.4
stress 7H9 with Isoniazid 0.025 ug/mL N.D. -0.3 N.D. +0.1 -0.3
nitrogen source Glycine 10 mM (N) N.D. -0.5 N.D. -0.2 +0.2
carbon source Stearic 100 uM (C) N.D. -0.2 N.D. -0.4 +0.1
nitrogen source L-Alanine 10 mM (N) N.D. -0.7 N.D. +0.1 +0.2
nitrogen source Glycine 10 mM (N) N.D. -0.2 N.D. -0.2 +0.2
stress 7H9 with Isoniazid 0.025 ug/mL N.D. -0.1 N.D. +0.4 -0.4
nitrogen source L-Glutamic 10 mM (N) N.D. -0.4 N.D. -0.2 +0.4
nitrogen source L-Alanine 10 mM (N) N.D. -0.6 N.D. -0.0 +0.5
stress 7H9 with Hygromycin B 0.0095 mM N.D. -0.4 N.D. -0.3 +0.6
stress 7H9 with Ethambutol 0.75 ug/mL N.D. -0.1 N.D. +0.4 -0.2
nitrogen source L-Valine 10 mM (N) N.D. -0.4 N.D. +0.4 +0.2
nitrogen source L-Aspartic Acid 10 mM (N) N.D. -0.2 N.D. +0.0 +0.6
nitrogen source L-Asparagine 10 mM (N) N.D. +0.0 N.D. -0.1 +0.6
stress 7H9 with Delamanid 0.236 ug/mL N.D. +0.1 N.D. +0.2 +0.4
carbon source butyrate 10 mM (C) N.D. +0.3 N.D. +0.1 +0.3
nitrogen source L-Glutamine 10 mM (N) N.D. +0.3 N.D. +0.0 +0.3
nitrogen source L-Serine 10 mM (N) N.D. +0.3 N.D. +0.2 +0.5
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