Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv1736c and Rv1737c overlap by 4 nucleotidesRv1737c and Rv1738 are separated by 286 nucleotidesRv1738 and Rv1739c are separated by 13 nucleotidesRv1739c and Rv1740 are separated by 67 nucleotides Rv1736c: Rv1736c - Probable nitrate reductase NarX, at 1,962,228 to 1,964,186 Rv1736c Rv1737c: Rv1737c - Possible nitrate/nitrite transporter NarK2, at 1,964,183 to 1,965,370 Rv1737c Rv1738: Rv1738 - Conserved protein, at 1,965,657 to 1,965,941 Rv1738 Rv1739c: Rv1739c - Probable sulphate-transport transmembrane protein ABC transporter, at 1,965,955 to 1,967,637 Rv1739c Rv1740: Rv1740 - Possible antitoxin VapB34, at 1,967,705 to 1,967,917 Rv1740
Group Condition Rv1736c Rv1737c Rv1738 Rv1739c Rv1740
stress 7H9 with Ofloxacin 0.8 ug/mL -0.1 +0.1 N.D. -0.2 -1.3
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -0.2 +0.1 N.D. -0.3 -0.9
stress 7H9 with Linezolid 0.44 ug/mL -0.1 -0.3 N.D. -0.3 -0.6
stress 7H9 with Ciprofloxacin Hydrochloride 0.001 mM -0.2 -0.1 N.D. -0.0 -0.9
stress 7H9 with EDTA (disodium salt) 0.2 mM -0.0 +0.2 N.D. -0.5 -0.7
stress 7H9 with Dicloxacillin 0.0069 mM -0.1 +0.0 N.D. -0.2 -0.7
no stress control no stress control -0.2 -0.1 N.D. +0.1 -0.8
stress 7H9 with Bedaquiline 0.15 ug/mL -0.1 +0.1 N.D. -0.2 -0.8
stress 7H9 with Chlorpromazine 0.054 mM -0.2 +0.2 N.D. -0.3 -0.7
no stress control no stress control -0.2 -0.2 N.D. +0.1 -0.6
stress 7H9 with Irgasan 0.065 mM +0.3 -0.2 N.D. +0.2 -1.1
carbon source oleate 200uM (C) -0.2 -0.1 N.D. +0.2 -0.8
stress 7H9 with Antimycin A 0.0186 mM +0.3 -0.5 N.D. +0.1 -0.5
stress 7H9 with Sulfamethizole 0.026 mM +0.1 +0.2 N.D. -0.1 -0.6
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM -0.0 +0.3 N.D. +0.0 -0.8
stress 7H9 with Phenazine methosulfate 0.0054 mM -0.1 +0.3 N.D. -0.0 -0.6
carbon source L-Asparagine (C) -0.1 +0.4 N.D. -0.1 -0.5
stress 7H9 with Cloxacillin 0.0386 mM +0.1 -0.0 N.D. +0.4 -0.7
stress 7H9 with nitrite 5 mM -0.3 +0.3 N.D. +0.1 -0.5
pH 7H9 pH 5.5 +0.0 -0.3 N.D. -0.3 +0.4
stress 7H9 with methylglyoxal 1.2 mM +0.1 +0.4 N.D. +0.2 -0.9
stress 7H9 with Chloramphenicol 0.01 mM +0.2 -0.1 N.D. +0.3 -0.6
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM -0.1 +0.5 N.D. +0.2 -0.6
stress 7H9 with Hygromycin B 0.0095 mM -0.1 +0.3 N.D. -0.3 +0.3
nitrogen source L-Asparagine 10 mM (N) -0.3 +0.6 N.D. +0.1 -0.0
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 +0.1 -0.2 N.D. +0.2 +0.5
no stress control no stress control -0.1 +0.7 N.D. -0.2 +0.4
carbon source Palmitic 100 uM (C) +0.1 -0.1 N.D. +0.2 +1.1
stress 7H9 with Phenazine methosulfate 0.0054 mM +0.3 +0.4 N.D. -0.2 +0.8
stress 7H9 with Doxycycline hyclate 0.0035 mM +0.1 +0.7 N.D. +0.4 +0.5
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