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Protein
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Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Number of genes on each side:
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv1661 and Rv1662 are separated by 19 nucleotides
Rv1662 and Rv1663 overlap by 1 nucleotides
Rv1663 and Rv1664 are separated by 5 nucleotides
Rv1664 and Rv1665 are separated by 146 nucleotides
Rv1661: Rv1661 - Probable polyketide synthase Pks7, at 1,875,304 to 1,881,684
Rv1661
Rv1662: Rv1662 - Probable polyketide synthase Pks8, at 1,881,704 to 1,886,512
Rv1662
Rv1663: Rv1663 - Probable polyketide synthase Pks17, at 1,886,512 to 1,888,020
Rv1663
Rv1664: Rv1664 - Probable polyketide synthase Pks9, at 1,888,026 to 1,891,079
Rv1664
Rv1665: Rv1665 - Chalcone synthase Pks11, at 1,891,226 to 1,892,287
Rv1665
Group
Condition
Rv1661
Rv1662
Rv1663
Rv1664
Rv1665
nitrogen source
L-Glutamic 10 mM (N)
-0.4
-0.4
-0.5
-0.1
-0.3
stress
7H9 with Ethionamide 0.1 ug/mL
+0.1
-0.6
-0.2
-0.3
-0.8
no stress control
no stress control
+0.1
-0.0
-0.8
-0.2
-0.7
stress
7H9 with Phenazine ethosulfate 0.0137 mM
+0.0
-0.4
-0.4
-0.2
-0.6
stress
7H9 with Norfloxacin 0.125 mM
-0.1
-1.2
+0.2
-0.1
-0.0
stress
7H9 with Moxifloxacin 0.121 ug/mL
-0.3
-0.6
+0.2
-0.3
-0.2
stress
7H9 with Dibucaine 0.21 mM
+0.2
-0.5
-0.3
-0.0
-0.5
stress
7H9 with Novobiocin 0.004 mM
-0.1
+0.2
-0.2
-0.5
-0.5
stress
7H9 with copper (II) chloride 0.08 mM
-0.7
+0.1
+0.2
-0.3
-0.5
nitrogen source
Glycine 10 mM (N)
-0.1
+0.3
-0.5
-0.3
-0.3
stress
7H9 with Chlorhexidine diacetate salt 0.0021 mM
+0.3
-0.1
-0.7
+0.1
-0.4
stress
7H9 with Dibucaine 0.21 mM
-0.3
-0.9
+0.5
+0.2
-0.2
stress
7H9 with Meropenem 9.6 ug/mL
-0.2
+0.5
-0.4
-0.1
-0.4
stress
7H9 with Pyrazinamide 50 ug/mL; pH 5.5
+0.3
-0.4
-0.1
+0.4
-0.5
nitrogen source
Glycine 10 mM (N)
+0.2
+0.5
-0.6
-0.2
-0.2
nitrogen source
Urea 10mM (N)
+0.5
-0.3
-0.3
-0.4
+0.2
stress
7H9 with Thioridazine 0.028 mM
-0.0
+0.7
-0.5
+0.1
-0.4
stress
7H9 with Cloxacillin 0.0386 mM
+0.1
-0.4
-0.4
-0.2
+0.7
no stress control
no stress control
-0.4
+0.5
-0.3
-0.2
+0.3
stress
7H9 with nitrite 3 mM; pH 5.5
+0.2
+0.7
-0.7
-0.1
-0.2
stress
7H9 with Dodecyl Sulfate 0.02 vol%
+0.1
+0.8
-0.2
-0.2
-0.5
stress
7H9 with Dimethyl Sulfoxide 1 vol%
-0.3
+0.8
-0.2
-0.2
-0.1
stress
7H9 with Lomefloxacin 0.0035 mM
-0.2
+0.8
-0.6
-0.2
+0.4
no stress control
no stress control
-0.1
+0.8
-0.4
-0.2
+0.1
stress
7H9 with Sisomicin 0.07 mM
-0.2
-0.6
+0.4
-0.1
+0.6
no stress control
no stress control
-0.0
-0.0
+0.6
-0.7
+0.3
pH
pH 5.5
+0.0
+1.1
-0.2
-0.0
-0.5
no stress control
no stress control
+0.1
+1.0
-0.4
+0.2
-0.3
stress
7H9 with Levofloxacin 0.3 ug/mL
-0.3
-0.3
+0.6
+0.1
+0.7
stress
7H9 with Moxifloxacin 0.121 ug/mL
-0.2
+0.6
+0.1
+0.0
+0.6
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