Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv1643 and Rv1644 are separated by 32 nucleotidesRv1644 and Rv1645c are separated by 10 nucleotidesRv1645c and Rv1646 are separated by 309 nucleotidesRv1646 and Rv1647 are separated by 77 nucleotides Rv1643: Rv1643 - 50S ribosomal protein L20 RplT, at 1,853,184 to 1,853,573 Rv1643 Rv1644: Rv1644 - Possible 23S rRNA methyltransferase TsnR, at 1,853,606 to 1,854,388 Rv1644 Rv1645c: Rv1645c - Conserved hypothetical protein, at 1,854,399 to 1,855,454 Rv1645c Rv1646: Rv1646 - PE family protein PE17, at 1,855,764 to 1,856,696 Rv1646 Rv1647: Rv1647 - Adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase), at 1,856,774 to 1,857,724 Rv1647
Group Condition Rv1643 Rv1644 Rv1645c Rv1646 Rv1647
carbon source heptadecanoic 250 uM (C) N.D. -0.2 -0.2 -0.6 -0.3
carbon source Stearic 100 uM (C) N.D. +0.1 -0.1 -0.4 -0.5
carbon source propionate (C) N.D. -0.4 -0.2 -0.2 -0.2
carbon source oleate 200uM (C) N.D. -0.0 -0.0 -0.7 -0.1
stress 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM N.D. -0.6 -0.0 -0.2 +0.2
stress 7H9 with hypochlorite 0.4 vol% N.D. -0.1 +0.1 +0.0 -0.7
stress 7H9 with Zinc Pyrithione 0.00072 mM N.D. -0.4 +0.1 -0.4 +0.1
carbon source cholesterol 100uM (C) N.D. -0.5 +0.0 +0.3 -0.3
stress 7H9 with copper (II) chloride 0.08 mM N.D. -0.3 -0.2 -0.1 +0.2
stress 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM N.D. -0.5 -0.0 -0.1 +0.4
stress 7H9 with Menadione 0.005 mM N.D. -0.5 -0.1 +0.2 +0.2
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 N.D. +0.3 +0.1 -0.0 -0.5
stress 7H9 with 2,4-Dinitrophenol 0.1503 mM N.D. +0.1 -0.0 -0.4 +0.5
stress 7H9 with Cumene hydroperoxide 0.05 mM N.D. +0.4 +0.1 -0.4 +0.1
stress 7H9 with Hydrogen peroxide 3.97 mM N.D. -0.2 -0.2 +0.2 +0.4
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM N.D. +0.3 -0.1 -0.3 +0.3
pH pH 4.5 N.D. +0.3 -0.1 +0.3 -0.2
stress 7H9 with Sisomicin 0.07 mM N.D. +0.5 -0.2 -0.1 +0.1
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM N.D. +0.5 -0.0 -0.2 +0.2
pH pH 5.5 N.D. +0.3 +0.1 +0.4 -0.3
stress 7H9 with Pretomanid 0.213 ug/mL N.D. +0.4 +0.1 -0.2 +0.3
pH 7H9 pH 5.5 N.D. +0.3 +0.3 -0.1 +0.2
nitrogen source L-Glutamic 10 mM (N) N.D. +0.4 -0.0 -0.1 +0.4
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 N.D. -0.1 +0.2 +0.4 +0.3
stress 7H9 with Cetrimonium bromide 0.015 vol% N.D. +0.3 -0.1 +0.2 +0.5
stress 7H9 with Linezolid 0.44 ug/mL N.D. +1.3 +0.0 -0.2 -0.0
stress 7H9 with Linezolid 0.3 ug/mL N.D. +1.5 -0.1 -0.1 -0.1
stress 7H9 with Linezolid 0.44 ug/mL N.D. +1.5 -0.1 -0.0 +0.2
stress 7H9 with Sutezolid 0.12 ug/mL N.D. +1.4 +0.1 -0.1 +0.2
stress 7H9 with Linezolid 0.3 ug/mL N.D. +1.6 +0.0 +0.2 -0.0
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