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Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv1563c and Rv1564c are separated by 3 nucleotides
Rv1564c and Rv1565c are separated by 38 nucleotides
Rv1565c and Rv1566c are separated by 98 nucleotides
Rv1566c and Rv1567c are separated by 239 nucleotides
Rv1563c: Rv1563c - Maltooligosyltrehalose synthase TreY, at 1,767,135 to 1,769,432
Rv1563c
Rv1564c: Rv1564c - Probable maltooligosyltrehalose synthase TreX, at 1,769,436 to 1,771,601
Rv1564c
Rv1565c: Rv1565c - Conserved hypothetical membrane protein, at 1,771,640 to 1,773,829
Rv1565c
Rv1566c: Rv1566c - Possible Inv protein, at 1,773,928 to 1,774,620
Rv1566c
Rv1567c: Rv1567c - Probable hypothetical membrane protein, at 1,774,860 to 1,775,144
Rv1567c
Group
Condition
Rv1563c
Rv1564c
Rv1565c
Rv1566c
Rv1567c
carbon source
Glycerol (C)
-0.2
-0.1
-1.9
-1.0
-0.2
stress
7H9 with Ethambutol 0.75 ug/mL
+0.2
+0.3
-3.1
-0.5
-0.2
carbon source
Glycerol (C)
-0.1
-0.1
-1.4
-1.1
-0.5
stress
7H9 with Ethambutol 0.75 ug/mL
+0.1
+0.2
-3.0
-0.5
-0.0
stress
7H9 with Clofazimine 0.072 ug/mL
+0.4
-0.0
-1.7
-1.3
-0.2
stress
7H9 with Econazole nitrate salt 0.0082 mM
+0.3
-0.0
-1.2
-1.6
-0.3
carbon source
L-Asparagine (C)
-0.3
+0.0
-1.4
-0.5
-0.6
stress
7H9 with Pyrazinamide 50 ug/mL; pH 5.5
+0.3
-0.3
-1.8
-0.7
-0.2
stress
7H9 with Econazole nitrate salt 0.0082 mM
+0.3
-0.1
-1.4
-1.4
-0.0
stress
7H9 with Pyrazinamide 50 ug/mL; pH 5.5
-0.1
-0.2
-1.0
-0.7
-0.5
stress
7H9 with Tetrazolium violet 0.065 mM
-0.1
-0.3
-0.5
-1.2
-0.3
nitrogen source
L-Asparagine 10 mM (N)
-0.4
+0.4
-1.3
-0.9
-0.1
stress
7H9 with Clarithromycin 0.967 ug/mL
-0.2
+0.1
-0.7
-1.4
-0.0
stress
7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM
+0.5
+0.0
-1.5
-0.5
-0.6
stress
7H9 with Ramoplanin 0.009 mM
+0.5
-0.1
-1.1
-1.7
+0.2
carbon source
L-Asparagine (C)
+0.2
+0.1
-1.0
-0.7
-0.7
stress
7H9 with Plumbagin 0.01 mM
-0.3
-0.1
-1.1
-0.7
+0.1
stress
7H9 with Delamanid 0.236 ug/mL
+0.2
+0.0
-1.5
-0.7
-0.1
stress
7H9 with Vancomycin Hydrochloride from Streptomyces orientalis 0.012 mM
+0.1
+0.2
-0.9
-1.0
-0.2
stress
7H9 with Ethionamide 0.1 ug/mL
+0.2
-0.8
-0.9
+0.4
-0.6
stress
7H9 with Clofazimine 0.45 ug/mL
+0.2
+0.4
-1.0
-1.1
-0.2
nitrogen source
L-Glutamine 10 mM (N)
-0.1
+0.3
-1.0
-0.9
-0.0
carbon source
butyrate 10 mM (C)
+0.3
+0.1
-1.1
-0.6
-0.3
carbon source
butyrate 10 mM (C)
+0.1
+0.3
-0.9
-0.9
-0.1
stress
7H9 with methylglyoxal 1.2 mM
+0.1
-0.3
+0.5
-1.4
-0.1
stress
7H9 with Irgasan 0.065 mM
-0.4
-0.1
-1.2
+0.5
+0.2
stress
7H9 with Ciprofloxacin Hydrochloride 0.001 mM
+0.3
+0.1
+1.0
-1.3
-0.1
stress
7H9 with Ciprofloxacin Hydrochloride 0.0012 mM
+0.2
-0.3
+1.0
-0.9
+0.0
stress
7H9 with Isoniazid 0.025 ug/mL
+0.5
-0.3
-0.7
+0.8
-0.2
stress
7H9 with methylglyoxal 1.2 mM
+0.5
-0.1
+0.6
-0.9
+0.3
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