Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv1536 and Rv1537 are separated by 211 nucleotidesRv1537 and Rv1538c overlap by 36 nucleotidesRv1538c and Rv1539 are separated by 51 nucleotidesRv1539 and Rv1540 overlap by 8 nucleotides Rv1536: Rv1536 - Isoleucyl-tRNA synthetase IleS, at 1,736,519 to 1,739,644 Rv1536 Rv1537: Rv1537 - Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)), at 1,739,856 to 1,741,247 Rv1537 Rv1538c: Rv1538c - Probable L-aparaginase AnsA, at 1,741,212 to 1,742,192 Rv1538c Rv1539: Rv1539 - Probable lipoprotein signal peptidase LspA, at 1,742,244 to 1,742,852 Rv1539 Rv1540: Rv1540 - Conserved hypothetical protein member of yabO/yceC/yfiI family, at 1,742,845 to 1,743,771 Rv1540
Group Condition Rv1536 Rv1537 Rv1538c Rv1539 Rv1540
carbon source propionate (C) N.D. -0.1 -4.2 N.D. N.D.
carbon source propionate (C) N.D. +0.5 -3.9 N.D. N.D.
carbon source L-Asparagine (C) N.D. -0.4 -2.9 N.D. N.D.
carbon source L-Asparagine (C) N.D. -0.2 -3.0 N.D. N.D.
carbon source Valeric 10 mM (C) N.D. +0.1 -2.4 N.D. N.D.
nitrogen source L-Asparagine 10 mM (N) N.D. -0.7 -1.2 N.D. N.D.
carbon source D-Lactate 10 mM (C) N.D. +0.1 -2.0 N.D. N.D.
carbon source D-Lactate 10 mM (C) N.D. -0.0 -1.8 N.D. N.D.
carbon source casaminos 1 mg/mL (C) N.D. -0.2 -1.6 N.D. N.D.
carbon source heptadecanoic 250 uM (C) N.D. -0.1 -1.5 N.D. N.D.
carbon source Palmitic 100 uM (C) N.D. -0.9 -0.8 N.D. N.D.
carbon source casaminos 1 mg/mL (C) N.D. -0.4 -1.3 N.D. N.D.
carbon source L-Aspartic Acid (C) N.D. -0.4 -1.2 N.D. N.D.
carbon source D,L-Malic Acid 10 mM (C) N.D. +0.0 -1.6 N.D. N.D.
carbon source L-Aspartic Acid (C) N.D. -0.0 -1.5 N.D. N.D.
carbon source heptadecanoic 250 uM (C) N.D. +0.1 -1.6 N.D. N.D.
carbon source pyruvate (C) N.D. -0.1 -1.4 N.D. N.D.
carbon source D-Glucose (C) N.D. +0.2 -1.6 N.D. N.D.
nitrogen source L-Asparagine 10 mM (N) N.D. +0.4 -1.8 N.D. N.D.
carbon source D-Glucose (C) N.D. +0.1 -1.4 N.D. N.D.
carbon source L-Glutamic (C) N.D. +0.3 -1.5 N.D. N.D.
carbon source acetate (C) N.D. +0.4 -1.4 N.D. N.D.
carbon source L-Glutamic (C) N.D. +0.4 -1.2 N.D. N.D.
nitrogen source L-Aspartic Acid 10 mM (N) N.D. -0.7 +1.4 N.D. N.D.
stress 7H9 with Geneticin G418 0.35 mM N.D. -0.4 +1.2 N.D. N.D.
stress 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM N.D. +0.7 +0.8 N.D. N.D.
stress 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM N.D. +0.8 +0.9 N.D. N.D.
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM N.D. +0.8 +1.0 N.D. N.D.
stress 7H9 with Sisomicin 0.07 mM N.D. +0.3 +1.5 N.D. N.D.
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM N.D. +0.8 +1.5 N.D. N.D.
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