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Protein
Homologs
Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Number of genes on each side:
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv1531 and Rv1532c are separated by 76 nucleotides
Rv1532c and Rv1533 are separated by 59 nucleotides
Rv1533 and Rv1534 overlap by 4 nucleotides
Rv1534 and Rv1535 are separated by 564 nucleotides
Rv1531: Rv1531 - Conserved protein, at 1,732,473 to 1,733,039
Rv1531
Rv1532c: Rv1532c - Conserved hypothetical protein, at 1,733,116 to 1,733,550
Rv1532c
Rv1533: Rv1533 - Conserved protein, at 1,733,610 to 1,734,737
Rv1533
Rv1534: Rv1534 - Probable transcriptional regulator, at 1,734,734 to 1,735,411
Rv1534
Rv1535: Rv1535 - Unknown protein, at 1,735,976 to 1,736,212
Rv1535
Group
Condition
Rv1531
Rv1532c
Rv1533
Rv1534
Rv1535
stress
7H9 with Dodecyl Sulfate 0.02 vol%
-2.2
N.D.
+0.3
-0.4
-0.0
stress
7H9 with Linezolid 0.44 ug/mL
-2.1
N.D.
+0.0
+0.1
+0.1
stress
7H9 with Isoniazid 0.025 ug/mL
-2.2
N.D.
+0.4
-0.3
+0.2
stress
7H9 with Clofazimine 0.45 ug/mL
-1.5
N.D.
-0.1
-0.2
+0.0
stress
7H9 with Levofloxacin 0.3 ug/mL
-1.0
N.D.
-0.1
-0.6
-0.2
carbon source
propionate (C)
-1.1
N.D.
-0.2
-0.6
+0.2
stress
7H9 with para-aminosalicylic 0.086 ug/mL
-1.6
N.D.
+0.0
+0.2
-0.2
no stress control
no stress control
-1.5
N.D.
+0.2
-0.2
+0.1
nitrogen source
L-Valine 10 mM (N)
-1.7
N.D.
+0.4
+0.1
-0.3
stress
7H9 with nitrite 2.5 mM
-1.5
N.D.
+0.8
-0.6
-0.0
carbon source
propionate (C)
-1.5
N.D.
+0.1
-0.3
+0.6
stress
7H9 with Geneticin G418 0.35 mM
-1.9
N.D.
+0.8
+0.0
+0.1
stress
7H9 with hypochlorite 0.4 vol%
-1.1
N.D.
+0.4
-0.3
+0.0
stress
7H9 with Econazole nitrate salt 0.0082 mM
-0.8
N.D.
+0.5
-0.3
-0.1
stress
7H9 with Sisomicin 0.07 mM
+0.7
N.D.
-0.8
-0.4
-0.1
stress
7H9 with Rifampicin 0.00045 ug/mL
-1.2
N.D.
+0.3
+0.3
+0.1
stress
7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM
-1.3
N.D.
+0.5
+0.2
+0.3
carbon source
Glycerol (C)
-1.0
N.D.
+0.7
+0.2
+0.1
no stress control
no stress control
-0.3
N.D.
+0.9
-0.5
-0.2
carbon source
acetate (C)
-0.9
N.D.
+0.5
+0.2
+0.3
no stress control
no stress control
+0.6
N.D.
+0.8
-0.3
-0.1
stress
7H9 with Menadione 0.005 mM
+0.9
N.D.
+0.7
-0.2
-0.0
stress
7H9 with Spectinomycin 0.029 mM
+1.0
N.D.
+0.6
-0.2
-0.1
stress
7H9 with Moxifloxacin 0.121 ug/mL
+1.1
N.D.
+0.4
-0.2
+0.2
stress
7H9 with Dimethyl Sulfoxide 1 vol%
+0.7
N.D.
+0.8
+0.2
+0.2
stress
7H9 with Phenazine ethosulfate 0.0137 mM
+0.7
N.D.
+0.5
+0.7
+0.0
stress
7H9 with Ethambutol 0.75 ug/mL
+1.9
N.D.
+0.1
-0.1
+0.1
carbon source
D-Trehalose 10 mM (C)
+0.9
N.D.
+0.9
+0.1
+0.4
no stress control
no stress control
+2.0
N.D.
+0.3
+0.3
+0.0
nitrogen source
L-Glutamic 10 mM (N)
+1.3
N.D.
+0.9
+0.0
+0.5
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