Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv1531 and Rv1532c are separated by 76 nucleotidesRv1532c and Rv1533 are separated by 59 nucleotidesRv1533 and Rv1534 overlap by 4 nucleotidesRv1534 and Rv1535 are separated by 564 nucleotides Rv1531: Rv1531 - Conserved protein, at 1,732,473 to 1,733,039 Rv1531 Rv1532c: Rv1532c - Conserved hypothetical protein, at 1,733,116 to 1,733,550 Rv1532c Rv1533: Rv1533 - Conserved protein, at 1,733,610 to 1,734,737 Rv1533 Rv1534: Rv1534 - Probable transcriptional regulator, at 1,734,734 to 1,735,411 Rv1534 Rv1535: Rv1535 - Unknown protein, at 1,735,976 to 1,736,212 Rv1535
Group Condition Rv1531 Rv1532c Rv1533 Rv1534 Rv1535
stress 7H9 with Dodecyl Sulfate 0.02 vol% -2.2 N.D. +0.3 -0.4 -0.0
stress 7H9 with Linezolid 0.44 ug/mL -2.1 N.D. +0.0 +0.1 +0.1
stress 7H9 with Isoniazid 0.025 ug/mL -2.2 N.D. +0.4 -0.3 +0.2
stress 7H9 with Clofazimine 0.45 ug/mL -1.5 N.D. -0.1 -0.2 +0.0
stress 7H9 with Levofloxacin 0.3 ug/mL -1.0 N.D. -0.1 -0.6 -0.2
carbon source propionate (C) -1.1 N.D. -0.2 -0.6 +0.2
stress 7H9 with para-aminosalicylic 0.086 ug/mL -1.6 N.D. +0.0 +0.2 -0.2
no stress control no stress control -1.5 N.D. +0.2 -0.2 +0.1
nitrogen source L-Valine 10 mM (N) -1.7 N.D. +0.4 +0.1 -0.3
stress 7H9 with nitrite 2.5 mM -1.5 N.D. +0.8 -0.6 -0.0
carbon source propionate (C) -1.5 N.D. +0.1 -0.3 +0.6
stress 7H9 with Geneticin G418 0.35 mM -1.9 N.D. +0.8 +0.0 +0.1
stress 7H9 with hypochlorite 0.4 vol% -1.1 N.D. +0.4 -0.3 +0.0
stress 7H9 with Econazole nitrate salt 0.0082 mM -0.8 N.D. +0.5 -0.3 -0.1
stress 7H9 with Sisomicin 0.07 mM +0.7 N.D. -0.8 -0.4 -0.1
stress 7H9 with Rifampicin 0.00045 ug/mL -1.2 N.D. +0.3 +0.3 +0.1
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -1.3 N.D. +0.5 +0.2 +0.3
carbon source Glycerol (C) -1.0 N.D. +0.7 +0.2 +0.1
no stress control no stress control -0.3 N.D. +0.9 -0.5 -0.2
carbon source acetate (C) -0.9 N.D. +0.5 +0.2 +0.3
no stress control no stress control +0.6 N.D. +0.8 -0.3 -0.1
stress 7H9 with Menadione 0.005 mM +0.9 N.D. +0.7 -0.2 -0.0
stress 7H9 with Spectinomycin 0.029 mM +1.0 N.D. +0.6 -0.2 -0.1
stress 7H9 with Moxifloxacin 0.121 ug/mL +1.1 N.D. +0.4 -0.2 +0.2
stress 7H9 with Dimethyl Sulfoxide 1 vol% +0.7 N.D. +0.8 +0.2 +0.2
stress 7H9 with Phenazine ethosulfate 0.0137 mM +0.7 N.D. +0.5 +0.7 +0.0
stress 7H9 with Ethambutol 0.75 ug/mL +1.9 N.D. +0.1 -0.1 +0.1
carbon source D-Trehalose 10 mM (C) +0.9 N.D. +0.9 +0.1 +0.4
no stress control no stress control +2.0 N.D. +0.3 +0.3 +0.0
nitrogen source L-Glutamic 10 mM (N) +1.3 N.D. +0.9 +0.0 +0.5
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