Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

Add gene:

Number of genes on each side:  

Top 30 experiments (either direction), sorted by average fitness

Or view all 236 experiments or choose conditions or try the comparative fitness browser

500 ntRv1520 and Rv1521 are separated by 233 nucleotidesRv1521 and Rv1522c are separated by 118 nucleotidesRv1522c and Rv1523 are separated by 40 nucleotidesRv1523 and Rv1524 are separated by 29 nucleotides Rv1520: Rv1520 - Probable sugar transferase, at 1,711,028 to 1,712,068 Rv1520 Rv1521: Rv1521 - Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase), at 1,712,302 to 1,714,053 Rv1521 Rv1522c: Rv1522c - Probable conserved transmembrane transport protein MmpL12, at 1,714,172 to 1,717,612 Rv1522c Rv1523: Rv1523 - Probable methyltransferase, at 1,717,653 to 1,718,696 Rv1523 Rv1524: Rv1524 - Probable glycosyltransferase, at 1,718,726 to 1,719,970 Rv1524
Group Condition Rv1520 Rv1521 Rv1522c Rv1523 Rv1524
stress 7H9 with copper (II) chloride 0.08 mM -0.3 -0.3 +0.1 -0.0 -0.8
no stress control no stress control -0.3 -0.2 -0.1 -0.1 -0.3
stress 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM -0.1 +0.1 -0.1 -0.1 -0.6
pH pH 4.5 +0.0 +0.0 -0.2 +0.1 -0.6
stress 7H9 with Ofloxacin 0.8 ug/mL -0.1 +0.3 -0.0 -0.1 -0.6
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 +0.1 -0.3 +0.1 +0.3 -0.6
stress 7H9 with Ciprofloxacin Hydrochloride 0.001 mM -0.0 +0.4 -0.1 -0.1 -0.6
stress 7H9 with copper (II) chloride 0.08 mM -0.3 -0.1 +0.3 +0.1 -0.4
stress 7H9 with Bedaquiline 0.15 ug/mL +0.0 +0.3 -0.0 +0.1 -0.5
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -0.1 -0.3 -0.3 -0.0 +0.7
stress 7H9 with Econazole nitrate salt 0.0082 mM -0.1 -0.1 -0.1 -0.2 +0.6
stress 7H9 with 2,4-Dinitrophenol 0.1503 mM +0.1 -0.1 -0.3 -0.2 +0.6
stress 7H9 with Lomefloxacin 0.0035 mM -0.0 -0.1 -0.1 -0.2 +0.6
stress 7H9 with Dicloxacillin 0.0069 mM +0.1 -0.1 -0.1 -0.2 +0.6
nitrogen source L-Valine 10 mM (N) +0.0 -0.1 +0.1 -0.2 +0.6
stress 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM +0.2 -0.2 -0.1 +0.0 +0.4
pH 7H9 pH 5.5 -0.1 -0.2 +0.2 +0.3 +0.3
stress 7H9 with hypochlorite 0.4 vol% +0.2 -0.1 +0.1 -0.3 +0.5
stress 7H9 with Phenazine ethosulfate 0.0137 mM +0.0 -0.2 -0.1 +0.2 +0.6
stress 7H9 with Amikacin di2 ug/mL -0.0 +0.2 -0.2 +0.1 +0.5
stress 7H9 with Econazole nitrate salt 0.0082 mM +0.0 -0.2 +0.0 -0.0 +1.0
no stress control no stress control +0.1 +0.0 -0.1 -0.1 +0.8
nitrogen source Ammonium chloride 10mM (N) -0.1 +0.1 -0.0 +0.1 +0.8
stress 7H9 with 8-hydroxy-nitroquinoline 0.03 mM +0.0 -0.1 +0.1 +0.3 +0.5
no stress control no stress control +0.1 +0.1 -0.1 +0.4 +0.4
stress 7H9 with Antimycin A 0.0186 mM +0.1 -0.2 -0.0 +0.1 +0.8
stress 7H9 with Ciprofloxacin Hydrochloride 0.001 mM +0.2 +0.0 +0.1 -0.0 +0.7
stress 7H9 with Dibucaine 0.21 mM -0.1 -0.1 +0.0 +0.3 +0.8
stress 7H9 with Doxycycline hyclate 0.0035 mM +0.1 +0.1 +0.0 +0.2 +0.6
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 +0.2 +0.1 -0.1 +0.1 +0.9
remove
Rv1520
plot
remove
Rv1521
plot
remove
Rv1522c
remove
Rv1523
plot
remove
Rv1524
plot