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Protein
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Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Number of genes on each side:
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv1520 and Rv1521 are separated by 233 nucleotides
Rv1521 and Rv1522c are separated by 118 nucleotides
Rv1522c and Rv1523 are separated by 40 nucleotides
Rv1523 and Rv1524 are separated by 29 nucleotides
Rv1520: Rv1520 - Probable sugar transferase, at 1,711,028 to 1,712,068
Rv1520
Rv1521: Rv1521 - Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase), at 1,712,302 to 1,714,053
Rv1521
Rv1522c: Rv1522c - Probable conserved transmembrane transport protein MmpL12, at 1,714,172 to 1,717,612
Rv1522c
Rv1523: Rv1523 - Probable methyltransferase, at 1,717,653 to 1,718,696
Rv1523
Rv1524: Rv1524 - Probable glycosyltransferase, at 1,718,726 to 1,719,970
Rv1524
Group
Condition
Rv1520
Rv1521
Rv1522c
Rv1523
Rv1524
stress
7H9 with copper (II) chloride 0.08 mM
-0.3
-0.3
+0.1
-0.0
-0.8
no stress control
no stress control
-0.3
-0.2
-0.1
-0.1
-0.3
stress
7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM
-0.1
+0.1
-0.1
-0.1
-0.6
pH
pH 4.5
+0.0
+0.0
-0.2
+0.1
-0.6
stress
7H9 with Ofloxacin 0.8 ug/mL
-0.1
+0.3
-0.0
-0.1
-0.6
stress
7H9 with Pyrazinamide 50 ug/mL; pH 5.5
+0.1
-0.3
+0.1
+0.3
-0.6
stress
7H9 with Ciprofloxacin Hydrochloride 0.001 mM
-0.0
+0.4
-0.1
-0.1
-0.6
stress
7H9 with copper (II) chloride 0.08 mM
-0.3
-0.1
+0.3
+0.1
-0.4
stress
7H9 with Bedaquiline 0.15 ug/mL
+0.0
+0.3
-0.0
+0.1
-0.5
stress
7H9 with Hydrogen peroxide 2.5 mM; pH 5.5
-0.1
-0.3
-0.3
-0.0
+0.7
stress
7H9 with Econazole nitrate salt 0.0082 mM
-0.1
-0.1
-0.1
-0.2
+0.6
stress
7H9 with 2,4-Dinitrophenol 0.1503 mM
+0.1
-0.1
-0.3
-0.2
+0.6
stress
7H9 with Lomefloxacin 0.0035 mM
-0.0
-0.1
-0.1
-0.2
+0.6
stress
7H9 with Dicloxacillin 0.0069 mM
+0.1
-0.1
-0.1
-0.2
+0.6
nitrogen source
L-Valine 10 mM (N)
+0.0
-0.1
+0.1
-0.2
+0.6
stress
7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM
+0.2
-0.2
-0.1
+0.0
+0.4
pH
7H9 pH 5.5
-0.1
-0.2
+0.2
+0.3
+0.3
stress
7H9 with hypochlorite 0.4 vol%
+0.2
-0.1
+0.1
-0.3
+0.5
stress
7H9 with Phenazine ethosulfate 0.0137 mM
+0.0
-0.2
-0.1
+0.2
+0.6
stress
7H9 with Amikacin di2 ug/mL
-0.0
+0.2
-0.2
+0.1
+0.5
stress
7H9 with Econazole nitrate salt 0.0082 mM
+0.0
-0.2
+0.0
-0.0
+1.0
no stress control
no stress control
+0.1
+0.0
-0.1
-0.1
+0.8
nitrogen source
Ammonium chloride 10mM (N)
-0.1
+0.1
-0.0
+0.1
+0.8
stress
7H9 with 8-hydroxy-nitroquinoline 0.03 mM
+0.0
-0.1
+0.1
+0.3
+0.5
no stress control
no stress control
+0.1
+0.1
-0.1
+0.4
+0.4
stress
7H9 with Antimycin A 0.0186 mM
+0.1
-0.2
-0.0
+0.1
+0.8
stress
7H9 with Ciprofloxacin Hydrochloride 0.001 mM
+0.2
+0.0
+0.1
-0.0
+0.7
stress
7H9 with Dibucaine 0.21 mM
-0.1
-0.1
+0.0
+0.3
+0.8
stress
7H9 with Doxycycline hyclate 0.0035 mM
+0.1
+0.1
+0.0
+0.2
+0.6
stress
7H9 with Hydrogen peroxide 2.5 mM; pH 6.5
+0.2
+0.1
-0.1
+0.1
+0.9
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