Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv1496 and Rv1497 are separated by 52 nucleotidesRv1497 and Rv1498c are separated by 72 nucleotidesRv1498c and Rv1498A are separated by 213 nucleotidesRv1498A and Rv1499 are separated by 60 nucleotides Rv1496: Rv1496 - Possible transport system kinase, at 1,686,884 to 1,687,888 Rv1496 Rv1497: Rv1497 - Probable esterase LipL, at 1,687,941 to 1,689,230 Rv1497 Rv1498c: Rv1498c - Probable methyltransferase, at 1,689,303 to 1,689,920 Rv1498c Rv1498A: Rv1498A - Conserved protein, at 1,690,134 to 1,690,346 Rv1498A Rv1499: Rv1499 - Hypothetical protein, at 1,690,407 to 1,690,805 Rv1499
Group Condition Rv1496 Rv1497 Rv1498c Rv1498A Rv1499
no stress control no stress control -0.8 +0.2 -0.4 -0.2 +0.2
pH pH 5.5 -0.7 -0.2 +0.1 -0.3 +0.3
stress 7H9 with nitrite 1.5 mM; pH 5.5 -0.1 -0.2 -0.2 -0.6 +0.3
carbon source D-Lactate 10 mM (C) -0.7 -0.2 +0.0 +0.2 +0.1
stress 7H9 with Doxycycline hyclate 0.0035 mM -0.0 +0.4 -0.2 -0.2 -0.5
stress 7H9 with Tetrazolium violet 0.065 mM -0.3 +0.2 -0.4 +0.2 -0.2
stress 7H9 with Lomefloxacin 0.0035 mM -0.6 -0.2 +0.2 +0.2 -0.2
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -0.6 +0.1 -0.3 +0.0 +0.3
stress 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM -0.8 -0.1 +0.2 +0.0 +0.3
stress 7H9 with nitrite 1.5 mM; pH 5.5 -0.1 -0.3 +0.2 -0.4 +0.4
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 -0.2 -0.2 +0.1 -0.4 +0.6
stress 7H9 with Erythromycin 0.016 mM -0.6 +0.1 -0.1 +0.1 +0.3
stress 7H9 with nitrite 2.5 mM -0.4 +0.4 -0.2 +0.2 -0.1
stress 7H9 with Linezolid 0.3 ug/mL -0.3 +0.1 -0.3 +0.0 +0.6
stress 7H9 with Norfloxacin 0.125 mM +0.6 +0.1 -0.3 +0.0 -0.2
stress 7H9 with copper (II) chloride 0.08 mM -0.1 +0.5 -0.4 +0.2 -0.0
stress 7H9 with Geneticin G418 0.35 mM -0.2 +0.2 +0.3 +0.2 -0.2
stress 7H9 with nitrate 4 mM +0.4 +0.4 -0.3 -0.1 +0.1
stress 7H9 with Chloramphenicol 0.01 mM -0.6 +0.4 +0.1 +0.5 +0.0
carbon source Stearic 100 uM (C) +0.6 -0.1 -0.1 +0.3 -0.1
stress 7H9 with Amikacin di2 ug/mL +0.7 +0.2 +0.0 -0.4 +0.1
no stress control no stress control +0.3 -0.1 +0.4 -0.1 +0.4
stress 7H9 with Phenazine ethosulfate 0.0137 mM -0.2 +0.2 +0.2 +0.4 +0.2
stress 7H9 with Clofazimine 0.45 ug/mL +0.8 +0.1 +0.3 -0.0 -0.1
stress 7H9 with Antimycin A 0.0186 mM +0.3 +0.2 -0.1 +0.2 +0.4
stress 7H9 with Isoniazid 0.025 ug/mL -0.2 +0.0 +0.6 +0.1 +0.6
stress 7H9 with Dodecyl Sulfate 0.02 vol% +0.6 +0.3 -0.1 +0.3 -0.0
no stress control no stress control +0.9 -0.0 -0.2 +0.1 +0.4
stress 7H9 with Ofloxacin 0.8 ug/mL -0.0 +0.2 +0.5 -0.0 +0.7
nitrogen source Urea 10mM (N) +1.2 -0.1 +0.2 -0.1 +0.0
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