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Protein
Homologs
Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Number of genes on each side:
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv1496 and Rv1497 are separated by 52 nucleotides
Rv1497 and Rv1498c are separated by 72 nucleotides
Rv1498c and Rv1498A are separated by 213 nucleotides
Rv1498A and Rv1499 are separated by 60 nucleotides
Rv1496: Rv1496 - Possible transport system kinase, at 1,686,884 to 1,687,888
Rv1496
Rv1497: Rv1497 - Probable esterase LipL, at 1,687,941 to 1,689,230
Rv1497
Rv1498c: Rv1498c - Probable methyltransferase, at 1,689,303 to 1,689,920
Rv1498c
Rv1498A: Rv1498A - Conserved protein, at 1,690,134 to 1,690,346
Rv1498A
Rv1499: Rv1499 - Hypothetical protein, at 1,690,407 to 1,690,805
Rv1499
Group
Condition
Rv1496
Rv1497
Rv1498c
Rv1498A
Rv1499
no stress control
no stress control
-0.8
+0.2
-0.4
-0.2
+0.2
pH
pH 5.5
-0.7
-0.2
+0.1
-0.3
+0.3
stress
7H9 with nitrite 1.5 mM; pH 5.5
-0.1
-0.2
-0.2
-0.6
+0.3
carbon source
D-Lactate 10 mM (C)
-0.7
-0.2
+0.0
+0.2
+0.1
stress
7H9 with Doxycycline hyclate 0.0035 mM
-0.0
+0.4
-0.2
-0.2
-0.5
stress
7H9 with Tetrazolium violet 0.065 mM
-0.3
+0.2
-0.4
+0.2
-0.2
stress
7H9 with Lomefloxacin 0.0035 mM
-0.6
-0.2
+0.2
+0.2
-0.2
stress
7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM
-0.6
+0.1
-0.3
+0.0
+0.3
stress
7H9 with Ciprofloxacin Hydrochloride 0.0012 mM
-0.8
-0.1
+0.2
+0.0
+0.3
stress
7H9 with nitrite 1.5 mM; pH 5.5
-0.1
-0.3
+0.2
-0.4
+0.4
stress
7H9 with Hydrogen peroxide 2.5 mM; pH 6.5
-0.2
-0.2
+0.1
-0.4
+0.6
stress
7H9 with Erythromycin 0.016 mM
-0.6
+0.1
-0.1
+0.1
+0.3
stress
7H9 with nitrite 2.5 mM
-0.4
+0.4
-0.2
+0.2
-0.1
stress
7H9 with Linezolid 0.3 ug/mL
-0.3
+0.1
-0.3
+0.0
+0.6
stress
7H9 with Norfloxacin 0.125 mM
+0.6
+0.1
-0.3
+0.0
-0.2
stress
7H9 with copper (II) chloride 0.08 mM
-0.1
+0.5
-0.4
+0.2
-0.0
stress
7H9 with Geneticin G418 0.35 mM
-0.2
+0.2
+0.3
+0.2
-0.2
stress
7H9 with nitrate 4 mM
+0.4
+0.4
-0.3
-0.1
+0.1
stress
7H9 with Chloramphenicol 0.01 mM
-0.6
+0.4
+0.1
+0.5
+0.0
carbon source
Stearic 100 uM (C)
+0.6
-0.1
-0.1
+0.3
-0.1
stress
7H9 with Amikacin di2 ug/mL
+0.7
+0.2
+0.0
-0.4
+0.1
no stress control
no stress control
+0.3
-0.1
+0.4
-0.1
+0.4
stress
7H9 with Phenazine ethosulfate 0.0137 mM
-0.2
+0.2
+0.2
+0.4
+0.2
stress
7H9 with Clofazimine 0.45 ug/mL
+0.8
+0.1
+0.3
-0.0
-0.1
stress
7H9 with Antimycin A 0.0186 mM
+0.3
+0.2
-0.1
+0.2
+0.4
stress
7H9 with Isoniazid 0.025 ug/mL
-0.2
+0.0
+0.6
+0.1
+0.6
stress
7H9 with Dodecyl Sulfate 0.02 vol%
+0.6
+0.3
-0.1
+0.3
-0.0
no stress control
no stress control
+0.9
-0.0
-0.2
+0.1
+0.4
stress
7H9 with Ofloxacin 0.8 ug/mL
-0.0
+0.2
+0.5
-0.0
+0.7
nitrogen source
Urea 10mM (N)
+1.2
-0.1
+0.2
-0.1
+0.0
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