Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv1425 and Rv1426c are separated by 21 nucleotidesRv1426c and Rv1427c overlap by 1 nucleotidesRv1427c and Rv1428c are separated by 3 nucleotidesRv1428c and Rv1429 are separated by 118 nucleotides Rv1425: Rv1425 - Possible triacylglycerol synthase (diacylglycerol acyltransferase), at 1,599,658 to 1,601,037 Rv1425 Rv1426c: Rv1426c - Probable esterase LipO, at 1,601,059 to 1,602,321 Rv1426c Rv1427c: Rv1427c - Possible long-chain-fatty-acid--CoA ligase FadD12 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase), at 1,602,321 to 1,603,928 Rv1427c Rv1428c: Rv1428c - Conserved hypothetical protein, at 1,603,932 to 1,604,759 Rv1428c Rv1429: Rv1429 - Conserved protein, at 1,604,878 to 1,606,146 Rv1429
Group Condition Rv1425 Rv1426c Rv1427c Rv1428c Rv1429
stress 7H9 with Bedaquiline 0.15 ug/mL -0.1 -0.1 -0.1 -0.6 -0.1
stress 7H9 with Ethambutol 0.75 ug/mL -0.0 -0.4 -0.3 -0.2 +0.1
stress 7H9 with Linezolid 0.44 ug/mL -0.2 -0.2 -0.3 +0.1 -0.2
stress 7H9 with Sulfamethizole 0.026 mM -0.0 -0.1 -0.2 -0.2 -0.2
no stress control no stress control -0.1 -0.2 -0.1 -0.1 -0.3
stress 7H9 with Clarithromycin 0.967 ug/mL -0.0 -0.1 -0.3 -0.0 -0.2
stress 7H9 with Meropenem 9.6 ug/mL +0.1 -0.3 -0.0 -0.1 -0.1
stress 7H9 with Bedaquiline 0.15 ug/mL -0.2 +0.1 -0.2 -0.3 +0.1
carbon source heptadecanoic 250 uM (C) +0.2 -0.1 -0.2 -0.0 -0.2
carbon source Valeric 10 mM (C) +0.1 -0.2 -0.2 +0.3 -0.2
nitrogen source L-Glutamic 10 mM (N) +0.1 -0.3 +0.2 -0.3 +0.1
carbon source Palmitic 100 uM (C) +0.3 -0.0 +0.0 -0.2 -0.3
carbon source D-Trehalose 10 mM (C) -0.3 +0.2 -0.3 +0.0 +0.2
stress 7H9 with Sulfamethizole 0.026 mM -0.2 -0.1 +0.3 -0.0 -0.1
stress 7H9 with Isoniazid 0.025 ug/mL -0.1 +0.3 +0.1 -0.3 -0.0
carbon source D,L-Malic Acid 10 mM (C) -0.3 +0.3 -0.3 +0.2 +0.2
carbon source pyruvate (C) +0.1 +0.3 +0.1 -0.1 -0.2
carbon source D-Lactate 10 mM (C) -0.1 +0.4 -0.2 -0.1 +0.2
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.1 +0.6 -0.4 -0.0 -0.0
stress 7H9 with Pretomanid 0.213 ug/mL +0.1 -0.2 +0.3 +0.3 -0.1
carbon source D-Glucose (C) -0.2 +0.1 +0.2 +0.1 +0.1
stress 7H9 with Dimethyl Sulfoxide 1 vol% -0.0 -0.1 -0.1 +0.3 +0.4
no stress control no stress control -0.0 +0.2 +0.4 -0.3 +0.4
carbon source casaminos 1 mg/mL (C) -0.0 +0.4 +0.1 +0.1 +0.1
stress 7H9 with para-aminosalicylic 0.086 ug/mL +0.1 +0.3 +0.2 +0.1 +0.0
stress 7H9 with Clofazimine 0.45 ug/mL +0.0 -0.1 +0.4 +0.2 +0.2
no stress control no stress control +0.1 +0.2 +0.2 +0.3 -0.1
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.0 +0.1 +0.3 +0.1 +0.3
stress 7H9 with Ofloxacin 0.8 ug/mL +0.1 +0.1 +0.3 +0.1 +0.2
stress 7H9 with Ethionamide 0.1 ug/mL +0.2 +0.2 +0.5 +0.0 +0.2
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