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Protein
Homologs
Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv1366 and Rv1366A overlap by 32 nucleotides
Rv1366A and Rv1367c are separated by 71 nucleotides
Rv1367c and Rv1368 are separated by 374 nucleotides
Rv1368 and Rv1369c are separated by 188 nucleotides
Rv1366: Rv1366 - Hypothetical protein, at 1,538,390 to 1,539,211
Rv1366
Rv1366A: Rv1366A - Conserved protein, at 1,539,180 to 1,539,440
Rv1366A
Rv1367c: Rv1367c - Conserved protein, at 1,539,512 to 1,540,645
Rv1367c
Rv1368: Rv1368 - Probable conserved lipoprotein LprF, at 1,541,020 to 1,541,805
Rv1368
Rv1369c: Rv1369c - Probable transposase, at 1,541,994 to 1,542,980
Rv1369c
Group
Condition
Rv1366
Rv1366A
Rv1367c
Rv1368
Rv1369c
stress
7H9 with Ethionamide 0.1 ug/mL
-0.0
-1.2
-0.1
-0.5
N.D.
carbon source
Glycerol (C)
-0.2
-1.1
-0.1
-0.3
N.D.
nitrogen source
L-Valine 10 mM (N)
+0.1
-1.3
-0.2
-0.3
N.D.
stress
7H9 with Ethionamide 0.1 ug/mL
-0.2
-0.8
-0.2
-0.5
N.D.
nitrogen source
L-Asparagine 10 mM (N)
-0.1
-1.6
+0.0
+0.0
N.D.
stress
7H9 with Isoniazid 0.025 ug/mL
-0.0
-1.0
-0.2
-0.2
N.D.
stress
7H9 with Ofloxacin 0.8 ug/mL
+0.1
-0.9
-0.2
-0.4
N.D.
no stress control
no stress control
-0.0
-1.3
-0.1
-0.0
N.D.
stress
7H9 with Isoniazid 0.025 ug/mL
-0.1
-1.2
+0.0
-0.1
N.D.
no stress control
no stress control
-0.0
-0.7
-0.3
-0.3
N.D.
stress
7H9 with Ofloxacin 0.8 ug/mL
-0.2
-0.7
-0.1
-0.2
N.D.
nitrogen source
L-Glutamine 10 mM (N)
+0.2
-1.5
+0.1
+0.1
N.D.
no stress control
no stress control
-0.1
-0.9
-0.1
+0.0
N.D.
stress
7H9 with Delamanid 0.236 ug/mL
-0.2
-0.8
+0.0
-0.1
N.D.
nitrogen source
L-Aspartic Acid 10 mM (N)
+0.1
-1.1
+0.0
-0.0
N.D.
stress
7H9 with Moxifloxacin 0.121 ug/mL
+0.1
-1.0
-0.1
+0.1
N.D.
stress
7H9 with Bedaquiline 0.15 ug/mL
+0.2
-0.9
-0.2
-0.0
N.D.
carbon source
D-Lactate 10 mM (C)
-0.3
-0.8
+0.1
+0.1
N.D.
nitrogen source
L-Alanine 10 mM (N)
+0.3
-1.2
+0.1
+0.1
N.D.
stress
7H9 with Meropenem 9.6 ug/mL
+0.2
-0.7
-0.2
+0.0
N.D.
nitrogen source
L-Aspartic Acid 10 mM (N)
+0.1
-0.5
+0.2
+0.3
N.D.
stress
7H9 with Moxifloxacin 0.121 ug/mL
+0.1
+0.6
-0.2
-0.2
N.D.
stress
7H9 with Clofazimine 0.45 ug/mL
+0.3
+1.0
+0.1
-0.3
N.D.
stress
7H9 with Dimethyl Sulfoxide 1 vol%
-0.1
+1.0
-0.0
-0.0
N.D.
no stress control
no stress control
-0.1
+1.1
-0.0
+0.0
N.D.
stress
7H9 with Sulfaquinoxaline 0.097 mM
+0.1
+1.0
-0.1
-0.1
N.D.
nitrogen source
L-Serine 10 mM (N)
+0.1
+0.9
+0.1
+0.1
N.D.
stress
7H9 with Hygromycin B 0.0095 mM
+0.2
+1.1
+0.0
-0.0
N.D.
stress
7H9 with Rifampicin 0.014 ug/mL
+0.5
+0.5
+0.3
-0.1
N.D.
stress
7H9 with Rifampicin 0.014 ug/mL
+0.2
+1.2
+0.1
+0.0
N.D.
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