Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv1265 and Rv1266c are separated by 19 nucleotidesRv1266c and Rv1267c are separated by 340 nucleotidesRv1267c and Rv1268c are separated by 310 nucleotidesRv1268c and Rv1269c are separated by 222 nucleotides Rv1265: Rv1265 - Unknown protein, at 1,413,260 to 1,413,940 Rv1265 Rv1266c: Rv1266c - Probable transmembrane serine/threonine-protein kinase H PknH (protein kinase H) (STPK H), at 1,413,960 to 1,415,840 Rv1266c Rv1267c: Rv1267c - Probable transcriptional regulatory protein EmbR, at 1,416,181 to 1,417,347 Rv1267c Rv1268c: Rv1268c - Hypothetical protein, at 1,417,658 to 1,418,356 Rv1268c Rv1269c: Rv1269c - Conserved probable secreted protein, at 1,418,579 to 1,418,953 Rv1269c
Group Condition Rv1265 Rv1266c Rv1267c Rv1268c Rv1269c
stress 7H9 with Nickel (II) chloride 0.6 mM N.D. +0.0 +0.0 -0.3 -0.8
stress 7H9 with Benzethonium chloride 0.068 mM N.D. -0.0 -0.2 -0.3 -0.6
no stress control no stress control N.D. -0.1 +0.1 -0.0 -1.0
no stress control no stress control N.D. +0.2 -0.0 -0.4 -0.8
stress 7H9 with Econazole nitrate salt 0.0082 mM N.D. -0.1 -0.3 +0.1 -0.6
stress 7H9 with Sulfamethizole 0.026 mM N.D. +0.2 -0.0 -0.2 -0.8
pH pH 4.5 N.D. -0.2 -0.5 +0.2 -0.3
stress 7H9 with Nickel (II) chloride 0.6 mM N.D. +0.1 +0.2 -0.5 -0.6
stress 7H9 with Econazole nitrate salt 0.0082 mM N.D. -0.0 +0.2 +0.1 -0.9
no stress control no stress control N.D. +0.2 -0.4 -0.2 -0.3
stress 7H9 with Vancomycin Hydrochloride from Streptomyces orientalis 0.012 mM N.D. -0.0 -0.0 +0.3 -0.9
stress 7H9 with Erythromycin 0.016 mM N.D. +0.1 -0.3 +0.1 -0.5
stress 7H9 with nitrate 4 mM N.D. +0.3 +0.1 +0.0 -0.8
stress 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM N.D. +0.2 -0.3 +0.4 -0.5
carbon source Palmitic 100 uM (C) N.D. +0.0 +0.4 +0.3 -0.8
stress 7H9 with Dicloxacillin 0.0069 mM N.D. +0.3 -0.1 +0.4 -0.4
pH pH 5.5 N.D. +0.1 +0.1 -0.4 +0.4
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM N.D. +0.3 +0.2 +0.3 -0.6
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 N.D. +0.1 +0.2 -0.4 +0.4
stress 7H9 with Ciprofloxacin Hydrochloride 0.001 mM N.D. -0.2 -0.2 +0.1 +0.7
stress 7H9 with Dimethyl Sulfoxide 1 vol% N.D. +0.1 +0.4 -0.4 +0.5
stress 7H9 with Linezolid 0.44 ug/mL N.D. -0.0 -0.1 +0.2 +0.7
stress 7H9 with Clofazimine 0.45 ug/mL N.D. -0.2 +0.3 +0.3 +0.4
stress 7H9 with Hydrogen peroxide 3.97 mM N.D. -0.2 +0.1 +0.1 +0.8
nitrogen source Ammonium chloride 10mM (N) N.D. +0.1 -0.2 +0.4 +0.7
stress 7H9 with Zinc Pyrithione 0.00072 mM N.D. -0.0 -0.1 +0.6 +0.6
stress 7H9 with Zinc Pyrithione 0.00072 mM N.D. +0.1 -0.1 +0.3 +0.8
stress 7H9 with Plumbagin 0.01 mM N.D. -0.1 +0.1 +0.2 +0.9
stress 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM N.D. +0.0 -0.2 +0.1 +1.6
nitrogen source Urea 10mM (N) N.D. +0.1 -0.1 +0.5 +1.7
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