Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv1256c and Rv1257c are separated by 113 nucleotidesRv1257c and Rv1258c overlap by 4 nucleotidesRv1258c and Rv1259 overlap by 2 nucleotidesRv1259 and Rv1260 are separated by 1 nucleotides Rv1256c: Rv1256c - Probable cytochrome P450 130 Cyp130, at 1,403,386 to 1,404,603 Rv1256c Rv1257c: Rv1257c - Probable oxidoreductase, at 1,404,717 to 1,406,084 Rv1257c Rv1258c: Rv1258c - Probable conserved integral membrane transport protein, at 1,406,081 to 1,407,340 Rv1258c Rv1259: Rv1259 - Probable uracil DNA glycosylase, UdgB, at 1,407,339 to 1,408,238 Rv1259 Rv1260: Rv1260 - Probable oxidoreductase, at 1,408,240 to 1,409,358 Rv1260
Group Condition Rv1256c Rv1257c Rv1258c Rv1259 Rv1260
nitrogen source L-Valine 10 mM (N) -0.7 -0.2 -0.1 -2.3 +0.0
carbon source D-Lactate 10 mM (C) +0.1 -3.0 +0.3 -0.5 +0.3
carbon source L-Glutamine (C) -0.2 +0.1 +0.1 -2.0 -0.2
carbon source D-Lactate 10 mM (C) -0.1 -2.6 +0.4 +0.1 +0.2
carbon source acetate (C) -0.3 +0.1 -0.1 -0.8 -0.5
nitrogen source L-Alanine 10 mM (N) -0.1 -0.1 -0.1 -1.4 +0.2
nitrogen source Glycine 10 mM (N) +0.1 -0.3 -0.1 -1.4 +0.2
stress 7H9 with Delamanid 0.236 ug/mL -0.1 +0.0 +0.2 -1.1 -0.3
stress 7H9 with Rifampicin 0.014 ug/mL -0.3 -0.2 +0.2 -1.0 +0.0
no stress control no stress control +0.2 +0.2 +0.0 -1.4 -0.2
stress 7H9 with Clofazimine 0.072 ug/mL +0.1 +0.1 +0.0 -1.3 -0.1
carbon source Glycerol (C) -0.0 +0.1 +0.1 -1.5 +0.4
stress 7H9 with Streptomycin 0.178 ug/mL +0.2 -0.0 -2.5 +1.6 +0.0
stress 7H9 with Streptomycin 0.178 ug/mL +0.1 +0.2 -2.3 +1.3 +0.4
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.8 -0.1 -0.1 +1.9 -0.9
carbon source L-Lactate 10 mM (C) -0.2 -0.3 -0.0 -0.5 +1.1
stress 7H9 with Isoniazid 0.025 ug/mL -0.1 -0.4 -0.1 +1.9 -1.1
stress 7H9 with Ofloxacin 0.8 ug/mL -0.8 -0.1 +0.0 +1.6 -0.6
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.5 -0.2 -0.0 +1.6 -0.3
carbon source L-Asparagine (C) -0.2 -0.2 -0.1 +0.9 +0.2
stress 7H9 with para-aminosalicylic 0.086 ug/mL -0.2 +0.1 -0.1 +1.2 -0.1
stress 7H9 with Ethionamide 0.1 ug/mL -0.4 -0.0 +0.0 +1.6 -0.2
no stress control no stress control +0.1 -0.1 -0.1 +1.5 -0.3
stress 7H9 with Ethionamide 0.1 ug/mL -0.2 -0.2 +0.1 +2.5 -0.8
stress 7H9 with Isoniazid 0.025 ug/mL -0.4 -0.0 +0.0 +1.8 +0.1
stress 7H9 with Ofloxacin 0.8 ug/mL -0.5 -0.0 -0.0 +2.3 -0.3
no stress control no stress control -0.3 +0.1 -0.1 +2.3 -0.3
stress 7H9 with para-aminosalicylic 0.086 ug/mL +0.3 +0.1 -0.1 +1.4 -0.1
carbon source casaminos 1 mg/mL (C) -0.0 +0.1 -0.0 +1.2 +0.4
stress 7H9 with Levofloxacin 0.3 ug/mL +0.5 -0.2 +0.1 +2.6 -0.1
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