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Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv1255c and Rv1256c overlap by 1 nucleotides
Rv1256c and Rv1257c are separated by 113 nucleotides
Rv1257c and Rv1258c overlap by 4 nucleotides
Rv1258c and Rv1259 overlap by 2 nucleotides
Rv1255c: Rv1255c - Probable transcriptional regulatory protein, at 1,402,778 to 1,403,386
Rv1255c
Rv1256c: Rv1256c - Probable cytochrome P450 130 Cyp130, at 1,403,386 to 1,404,603
Rv1256c
Rv1257c: Rv1257c - Probable oxidoreductase, at 1,404,717 to 1,406,084
Rv1257c
Rv1258c: Rv1258c - Probable conserved integral membrane transport protein, at 1,406,081 to 1,407,340
Rv1258c
Rv1259: Rv1259 - Probable uracil DNA glycosylase, UdgB, at 1,407,339 to 1,408,238
Rv1259
Group
Condition
Rv1255c
Rv1256c
Rv1257c
Rv1258c
Rv1259
nitrogen source
L-Valine 10 mM (N)
-0.2
-0.7
-0.2
-0.1
-2.3
carbon source
D-Lactate 10 mM (C)
+0.1
+0.1
-3.0
+0.3
-0.5
carbon source
D-Lactate 10 mM (C)
-0.3
-0.1
-2.6
+0.4
+0.1
nitrogen source
L-Alanine 10 mM (N)
-0.4
-0.1
-0.1
-0.1
-1.4
no stress control
no stress control
-1.2
-0.1
+0.0
-0.0
-0.8
carbon source
L-Glutamine (C)
-0.1
-0.2
+0.1
+0.1
-2.0
stress
7H9 with Sulfamethizole 0.026 mM
-0.4
-0.3
-0.3
-0.1
-0.8
nitrogen source
Glycine 10 mM (N)
+0.1
+0.1
-0.3
-0.1
-1.4
stress
7H9 with Rifampicin 0.014 ug/mL
-0.3
-0.3
-0.2
+0.2
-1.0
carbon source
Glycerol (C)
-0.1
-0.0
+0.1
+0.1
-1.5
stress
7H9 with Delamanid 0.236 ug/mL
-0.3
-0.1
+0.0
+0.2
-1.1
no stress control
no stress control
-0.3
+0.2
+0.2
+0.0
-1.4
stress
7H9 with Clofazimine 0.072 ug/mL
-0.2
+0.1
+0.1
+0.0
-1.3
stress
7H9 with Clofazimine 0.45 ug/mL
-0.6
+0.1
+0.2
-0.1
-0.6
stress
7H9 with Streptomycin 0.178 ug/mL
+0.1
+0.1
+0.2
-2.3
+1.3
stress
7H9 with Streptomycin 0.178 ug/mL
+0.2
+0.2
-0.0
-2.5
+1.6
stress
7H9 with Ethionamide 0.1 ug/mL
-1.3
-0.4
-0.0
+0.0
+1.6
stress
7H9 with Isoniazid 0.025 ug/mL
-0.8
-0.4
-0.0
+0.0
+1.8
stress
7H9 with Moxifloxacin 0.121 ug/mL
-0.2
-0.5
-0.2
-0.0
+1.6
stress
7H9 with Moxifloxacin 0.121 ug/mL
-0.0
-0.8
-0.1
-0.1
+1.9
stress
7H9 with Isoniazid 0.025 ug/mL
-0.3
-0.1
-0.4
-0.1
+1.9
carbon source
casaminos 1 mg/mL (C)
-0.3
-0.0
+0.1
-0.0
+1.2
stress
7H9 with para-aminosalicylic 0.086 ug/mL
+0.2
-0.2
+0.1
-0.1
+1.2
stress
7H9 with Ofloxacin 0.8 ug/mL
+0.3
-0.8
-0.1
+0.0
+1.6
no stress control
no stress control
-0.2
+0.1
-0.1
-0.1
+1.5
stress
7H9 with Ethionamide 0.1 ug/mL
-0.9
-0.2
-0.2
+0.1
+2.5
no stress control
no stress control
-0.5
-0.3
+0.1
-0.1
+2.3
stress
7H9 with Ofloxacin 0.8 ug/mL
-0.3
-0.5
-0.0
-0.0
+2.3
stress
7H9 with para-aminosalicylic 0.086 ug/mL
+0.4
+0.3
+0.1
-0.1
+1.4
stress
7H9 with Levofloxacin 0.3 ug/mL
-0.7
+0.5
-0.2
+0.1
+2.6
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