Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv1218c and Rv1219c overlap by 11 nucleotidesRv1219c and Rv1220c are separated by 141 nucleotidesRv1220c and Rv1221 are separated by 262 nucleotidesRv1221 and Rv1222 are separated by 157 nucleotides Rv1218c: Rv1218c - Probable tetronasin-transport ATP-binding protein ABC transporter, at 1,361,798 to 1,362,733 Rv1218c Rv1219c: Rv1219c - Probable transcriptional regulatory protein, at 1,362,723 to 1,363,361 Rv1219c Rv1220c: Rv1220c - Probable methyltransferase, at 1,363,503 to 1,364,150 Rv1220c Rv1221: Rv1221 - Alternative RNA polymerase sigma factor SigE, at 1,364,413 to 1,365,186 Rv1221 Rv1222: Rv1222 - Anti-sigma factor RseA, at 1,365,344 to 1,365,808 Rv1222
Group Condition Rv1218c Rv1219c Rv1220c Rv1221 Rv1222
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.3 -0.4 -0.4 -0.5 -0.1
stress 7H9 with Sisomicin 0.07 mM -0.3 -0.6 -0.3 -0.5 -0.0
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.6 -0.2 -0.2 -0.0 -0.5
stress 7H9 with Levofloxacin 0.3 ug/mL -0.5 +0.2 -0.4 -0.3 -0.5
pH pH 4.5 -0.3 +0.1 -1.0 -0.2 +0.1
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -0.2 -0.3 -1.1 +0.6 -0.3
stress 7H9 with Ofloxacin 0.8 ug/mL -0.8 -0.4 +0.1 +0.1 -0.2
stress 7H9 with Ramoplanin 0.009 mM +0.1 -0.0 -0.6 +0.1 -0.8
stress 7H9 with copper (II) chloride 0.08 mM +0.1 -0.0 -0.9 +0.1 -0.5
carbon source casaminos 1 mg/mL (C) +0.2 +0.0 -0.8 -0.2 -0.4
stress 7H9 with Rifampicin 0.014 ug/mL +0.1 -0.2 -1.2 -0.0 +0.2
stress 7H9 with Sisomicin 0.07 mM -0.4 -0.0 -0.6 -0.6 +0.5
stress 7H9 with Norfloxacin 0.125 mM -0.4 -0.5 -0.7 +0.4 +0.2
carbon source D-Trehalose 10 mM (C) -0.3 -0.3 -0.7 +0.2 +0.2
stress 7H9 with Econazole nitrate salt 0.0082 mM -0.3 -0.1 -0.3 -0.7 +0.6
stress 7H9 with para-aminosalicylic 0.086 ug/mL -0.3 -0.2 -0.3 -0.4 +0.6
stress 7H9 with Rifampicin 0.00045 ug/mL +0.4 -0.0 -1.0 -0.2 +0.2
stress 7H9 with copper (II) chloride 0.08 mM +0.1 -0.0 -1.1 +0.2 +0.3
stress 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM -0.1 +0.3 -0.6 +0.3 -0.4
stress 7H9 with Dibucaine 0.21 mM -0.6 +0.4 -0.2 +0.2 -0.2
carbon source Stearic 100 uM (C) +0.1 -0.0 -0.6 +0.6 -0.6
stress 7H9 with Isoniazid 0.025 ug/mL -0.5 -0.5 +0.8 +0.0 +0.0
stress 7H9 with Antimycin A 0.0186 mM -0.1 -0.3 -0.5 +0.4 +0.3
stress 7H9 with Econazole nitrate salt 0.0082 mM -0.2 -0.2 -0.4 +0.1 +0.7
stress 7H9 with Rifampicin 0.014 ug/mL +0.2 +0.5 -1.0 -0.2 +0.4
no stress control no stress control -0.8 +0.1 -0.1 +0.2 +0.7
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -0.2 +0.1 -0.5 +0.7 +0.1
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 -0.6 +0.1 -0.3 +0.3 +0.6
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM -0.6 +0.2 -0.2 +0.2 +0.7
nitrogen source L-Glutamic 10 mM (N) +1.1 -0.3 +0.1 +0.0 -0.1
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