Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv1125 and Rv1126c are separated by 3 nucleotidesRv1126c and Rv1127c overlap by 4 nucleotidesRv1127c and Rv1128c are separated by 212 nucleotidesRv1128c and Rv1129c are separated by 101 nucleotides Rv1125: Rv1125 - Conserved hypothetical protein, at 1,248,082 to 1,249,326 Rv1125 Rv1126c: Rv1126c - Conserved protein, at 1,249,330 to 1,249,935 Rv1126c Rv1127c: Rv1127c - Probable pyruvate, phosphate dikinase PpdK, at 1,249,932 to 1,251,404 Rv1127c Rv1128c: Rv1128c - Conserved hypothetical protein, at 1,251,617 to 1,252,972 Rv1128c Rv1129c: Rv1129c - Probable transcriptional regulator protein, at 1,253,074 to 1,254,534 Rv1129c
Group Condition Rv1125 Rv1126c Rv1127c Rv1128c Rv1129c
carbon source propionate (C) -0.0 N.D. -1.0 -0.1 -4.6
carbon source propionate (C) +0.1 N.D. -1.6 +0.1 -3.9
carbon source Valeric 10 mM (C) +0.3 N.D. -1.0 -0.2 -4.4
carbon source Valeric 10 mM (C) +0.1 N.D. -0.2 -0.6 -3.6
stress 7H9 with Clofazimine 0.45 ug/mL -0.3 N.D. -3.0 -0.5 -0.1
nitrogen source L-Glutamic 10 mM (N) +0.0 N.D. -3.7 -0.4 +0.4
nitrogen source L-Asparagine 10 mM (N) -0.2 N.D. -3.4 -0.1 +0.1
carbon source Stearic 100 uM (C) +0.0 N.D. -2.1 -1.1 -0.1
nitrogen source Glycine 10 mM (N) -0.4 N.D. -3.0 -0.2 +0.3
carbon source heptadecanoic 250 uM (C) -0.0 N.D. -0.5 -0.2 -2.4
stress 7H9 with Clofazimine 0.45 ug/mL -0.1 N.D. -2.2 -0.3 -0.3
carbon source L-Aspartic Acid (C) +0.0 N.D. -3.1 +0.2 +0.1
carbon source heptadecanoic 250 uM (C) -0.2 N.D. +0.4 -0.7 -2.3
nitrogen source L-Aspartic Acid 10 mM (N) -0.2 N.D. -1.6 -0.8 +0.0
carbon source L-Lactate 10 mM (C) +0.2 N.D. -2.9 -0.1 +0.3
nitrogen source L-Serine 10 mM (N) -0.1 N.D. -2.2 -0.4 +0.2
carbon source L-Asparagine (C) +0.2 N.D. -2.1 -0.5 +0.1
nitrogen source L-Alanine 10 mM (N) -0.0 N.D. -1.8 -0.3 -0.1
nitrogen source L-Asparagine 10 mM (N) -0.1 N.D. -2.2 -0.2 +0.2
stress 7H9 with Isoniazid 0.025 ug/mL +0.1 N.D. -1.7 -0.5 -0.0
stress 7H9 with Clofazimine 0.072 ug/mL +0.1 N.D. -1.5 -0.4 -0.2
carbon source D-Glucose (C) +0.2 N.D. -2.3 +0.1 +0.1
carbon source D-Glucose (C) -0.0 N.D. -2.3 +0.3 +0.1
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.1 N.D. -1.9 +0.1 -0.0
carbon source Glycerol (C) -0.1 N.D. -1.9 +0.1 +0.1
nitrogen source Glycine 10 mM (N) -0.2 N.D. -1.5 -0.3 +0.4
stress 7H9 with Ethionamide 0.1 ug/mL +0.2 N.D. -1.6 -0.5 +0.2
stress 7H9 with Meropenem 9.6 ug/mL -0.1 N.D. -1.7 -0.1 +0.3
nitrogen source L-Aspartic Acid 10 mM (N) +0.3 N.D. -1.7 -0.2 +0.1
carbon source L-Glutamine (C) +0.4 N.D. -1.7 +0.0 +0.0
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