Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv1034c and Rv1035c are separated by 67 nucleotidesRv1035c and Rv1036c are separated by 33 nucleotidesRv1036c and Rv1037c are separated by 110 nucleotidesRv1037c and Rv1038c are separated by 26 nucleotides Rv1034c: Rv1034c - Probable transposase (fragment), at 1,158,918 to 1,159,307 Rv1034c Rv1035c: Rv1035c - Probable transposase (fragment), at 1,159,375 to 1,160,061 Rv1035c Rv1036c: Rv1036c - Probable IS1560 transposase (fragment), at 1,160,095 to 1,160,433 Rv1036c Rv1037c: Rv1037c - Putative ESAT-6 like protein EsxI (ESAT-6 like protein 1), at 1,160,544 to 1,160,828 Rv1037c Rv1038c: Rv1038c - ESAT-6 like protein EsxJ (ESAT-6 like protein 2), at 1,160,855 to 1,161,151 Rv1038c
Group Condition Rv1034c Rv1035c Rv1036c Rv1037c Rv1038c
no stress control no stress control N.D. -2.4 -0.1 N.D. N.D.
carbon source oleate 200uM (C) N.D. -1.4 +0.1 N.D. N.D.
stress 7H9 with Menadione 0.005 mM N.D. -0.9 -0.3 N.D. N.D.
nitrogen source L-Aspartic Acid 10 mM (N) N.D. -1.3 +0.1 N.D. N.D.
carbon source Palmitic 100 uM (C) N.D. -0.8 -0.2 N.D. N.D.
stress 7H9 with Levofloxacin 0.3 ug/mL N.D. -1.2 +0.2 N.D. N.D.
stress 7H9 with Menadione 0.005 mM N.D. -0.7 -0.3 N.D. N.D.
stress 7H9 with Isoniazid 0.025 ug/mL N.D. -0.6 -0.4 N.D. N.D.
stress 7H9 with Moxifloxacin 0.121 ug/mL N.D. -0.9 -0.2 N.D. N.D.
stress 7H9 with Moxifloxacin 0.121 ug/mL N.D. -0.8 -0.1 N.D. N.D.
carbon source Valeric 10 mM (C) N.D. -0.8 -0.1 N.D. N.D.
stress 7H9 with Ofloxacin 0.8 ug/mL N.D. -0.9 +0.0 N.D. N.D.
carbon source oleate 200uM (C) N.D. -0.8 +0.3 N.D. N.D.
stress 7H9 with Novobiocin 0.004 mM N.D. -0.7 +0.3 N.D. N.D.
stress 7H9 with Linezolid 0.44 ug/mL N.D. +0.5 -0.5 N.D. N.D.
stress 7H9 with Novobiocin 0.004 mM N.D. -0.5 +0.5 N.D. N.D.
stress 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM N.D. +0.8 -0.3 N.D. N.D.
no stress control no stress control N.D. +0.8 -0.2 N.D. N.D.
stress 7H9 with nitrite 1.5 mM; pH 5.5 N.D. +1.1 -0.5 N.D. N.D.
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 N.D. +0.9 -0.2 N.D. N.D.
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 N.D. +1.0 -0.3 N.D. N.D.
pH pH 5.5 N.D. +1.1 -0.4 N.D. N.D.
carbon source Palmitic 100 uM (C) N.D. +0.9 -0.1 N.D. N.D.
stress 7H9 with Cloxacillin 0.0386 mM N.D. +0.9 -0.1 N.D. N.D.
stress 7H9 with Sulfamethizole 0.026 mM N.D. +0.7 +0.3 N.D. N.D.
stress 7H9 with Geneticin G418 0.35 mM N.D. +0.9 +0.2 N.D. N.D.
stress 7H9 with nitrite 3 mM; pH 5.5 N.D. +1.3 -0.2 N.D. N.D.
nitrogen source L-Serine 10 mM (N) N.D. +0.9 +0.1 N.D. N.D.
stress 7H9 with Tetrazolium violet 0.065 mM N.D. +1.2 +0.3 N.D. N.D.
carbon source Stearic 100 uM (C) N.D. +1.9 -0.1 N.D. N.D.
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