Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv1000c and Rv1001 are separated by 36 nucleotidesRv1001 and Rv1002c are separated by 34 nucleotidesRv1002c and Rv1003 are separated by 82 nucleotidesRv1003 and Rv1004c are separated by 9 nucleotides Rv1000c: Rv1000c - Conserved hypothetical protein, at 1,116,531 to 1,117,148 Rv1000c Rv1001: Rv1001 - Probable arginine deiminase ArcA (adi) (ad) (arginine dihydrolase), at 1,117,185 to 1,118,393 Rv1001 Rv1002c: Rv1002c - Conserved membrane protein, at 1,118,428 to 1,119,939 Rv1002c Rv1003: Rv1003 - Conserved protein, at 1,120,022 to 1,120,879 Rv1003 Rv1004c: Rv1004c - Probable membrane protein, at 1,120,889 to 1,122,148 Rv1004c
Group Condition Rv1000c Rv1001 Rv1002c Rv1003 Rv1004c
stress 7H9 with Isoniazid 0.025 ug/mL -0.1 -0.7 N.D. -3.8 -0.6
stress 7H9 with Ethionamide 0.1 ug/mL -0.2 -0.4 N.D. -0.9 -1.5
no stress control no stress control -0.0 -0.2 N.D. -1.3 -1.2
stress 7H9 with para-aminosalicylic 0.086 ug/mL -0.1 +0.0 N.D. -1.0 -0.9
nitrogen source L-Asparagine 10 mM (N) -0.0 +0.1 N.D. -1.2 -0.7
stress 7H9 with Streptomycin 0.178 ug/mL -0.2 -0.3 N.D. -1.2 -0.1
stress 7H9 with Dimethyl Sulfoxide 1 vol% +0.2 -0.1 N.D. -1.2 -0.5
no stress control no stress control -0.2 -0.3 N.D. -1.0 -0.2
no stress control no stress control -0.0 -0.3 N.D. -0.7 -0.6
stress 7H9 with Isoniazid 0.025 ug/mL -0.5 -0.1 N.D. -0.5 -0.4
carbon source L-Glutamine (C) +0.0 -0.1 N.D. -1.2 -0.3
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.2 +0.0 N.D. -0.2 -1.1
carbon source pyruvate (C) +0.1 -0.1 N.D. -1.4 -0.1
stress 7H9 with para-aminosalicylic 0.086 ug/mL -0.2 -0.2 N.D. -0.5 -0.5
stress 7H9 with Streptomycin 0.178 ug/mL -0.3 -0.5 N.D. -0.6 -0.0
stress 7H9 with Ethionamide 0.1 ug/mL -0.3 -0.6 N.D. +0.2 -0.6
carbon source D-Glucose (C) -0.1 +0.0 N.D. -1.6 +0.7
carbon source D,L-Malic Acid 10 mM (C) +0.3 +0.1 N.D. -0.9 -0.3
carbon source Valeric 10 mM (C) -0.0 -0.1 N.D. -1.0 +0.4
no stress control no stress control +0.3 +0.2 N.D. -1.7 +0.5
carbon source acetate (C) +0.0 +0.2 N.D. -1.2 +0.3
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.0 +0.2 N.D. -1.2 +0.3
carbon source acetate (C) +0.1 +0.3 N.D. -1.0 +0.2
stress 7H9 with Clarithromycin 0.967 ug/mL +0.2 +0.1 N.D. -0.8 +0.3
carbon source propionate (C) +0.2 +0.0 N.D. -0.8 +0.6
carbon source casaminos 1 mg/mL (C) -0.0 +0.2 N.D. -0.5 +0.7
stress 7H9 with Hygromycin B 0.0095 mM +0.0 -0.2 N.D. +1.0 -0.4
stress 7H9 with Rifampicin 0.00045 ug/mL -0.1 +0.4 N.D. -0.4 +1.0
stress 7H9 with Levofloxacin 0.3 ug/mL +0.1 +0.0 N.D. +1.0 -0.3
carbon source Stearic 100 uM (C) +0.0 -0.2 N.D. +1.2 +0.1
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