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Protein
Homologs
Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv1000c and Rv1001 are separated by 36 nucleotides
Rv1001 and Rv1002c are separated by 34 nucleotides
Rv1002c and Rv1003 are separated by 82 nucleotides
Rv1003 and Rv1004c are separated by 9 nucleotides
Rv1000c: Rv1000c - Conserved hypothetical protein, at 1,116,531 to 1,117,148
Rv1000c
Rv1001: Rv1001 - Probable arginine deiminase ArcA (adi) (ad) (arginine dihydrolase), at 1,117,185 to 1,118,393
Rv1001
Rv1002c: Rv1002c - Conserved membrane protein, at 1,118,428 to 1,119,939
Rv1002c
Rv1003: Rv1003 - Conserved protein, at 1,120,022 to 1,120,879
Rv1003
Rv1004c: Rv1004c - Probable membrane protein, at 1,120,889 to 1,122,148
Rv1004c
Group
Condition
Rv1000c
Rv1001
Rv1002c
Rv1003
Rv1004c
stress
7H9 with Isoniazid 0.025 ug/mL
-0.1
-0.7
N.D.
-3.8
-0.6
stress
7H9 with Ethionamide 0.1 ug/mL
-0.2
-0.4
N.D.
-0.9
-1.5
no stress control
no stress control
-0.0
-0.2
N.D.
-1.3
-1.2
stress
7H9 with para-aminosalicylic 0.086 ug/mL
-0.1
+0.0
N.D.
-1.0
-0.9
nitrogen source
L-Asparagine 10 mM (N)
-0.0
+0.1
N.D.
-1.2
-0.7
stress
7H9 with Streptomycin 0.178 ug/mL
-0.2
-0.3
N.D.
-1.2
-0.1
stress
7H9 with Dimethyl Sulfoxide 1 vol%
+0.2
-0.1
N.D.
-1.2
-0.5
no stress control
no stress control
-0.2
-0.3
N.D.
-1.0
-0.2
no stress control
no stress control
-0.0
-0.3
N.D.
-0.7
-0.6
stress
7H9 with Isoniazid 0.025 ug/mL
-0.5
-0.1
N.D.
-0.5
-0.4
carbon source
L-Glutamine (C)
+0.0
-0.1
N.D.
-1.2
-0.3
stress
7H9 with Moxifloxacin 0.121 ug/mL
-0.2
+0.0
N.D.
-0.2
-1.1
carbon source
pyruvate (C)
+0.1
-0.1
N.D.
-1.4
-0.1
stress
7H9 with para-aminosalicylic 0.086 ug/mL
-0.2
-0.2
N.D.
-0.5
-0.5
stress
7H9 with Streptomycin 0.178 ug/mL
-0.3
-0.5
N.D.
-0.6
-0.0
stress
7H9 with Ethionamide 0.1 ug/mL
-0.3
-0.6
N.D.
+0.2
-0.6
carbon source
D-Glucose (C)
-0.1
+0.0
N.D.
-1.6
+0.7
carbon source
D,L-Malic Acid 10 mM (C)
+0.3
+0.1
N.D.
-0.9
-0.3
carbon source
Valeric 10 mM (C)
-0.0
-0.1
N.D.
-1.0
+0.4
no stress control
no stress control
+0.3
+0.2
N.D.
-1.7
+0.5
carbon source
acetate (C)
+0.0
+0.2
N.D.
-1.2
+0.3
stress
7H9 with Moxifloxacin 0.121 ug/mL
-0.0
+0.2
N.D.
-1.2
+0.3
carbon source
acetate (C)
+0.1
+0.3
N.D.
-1.0
+0.2
stress
7H9 with Clarithromycin 0.967 ug/mL
+0.2
+0.1
N.D.
-0.8
+0.3
carbon source
propionate (C)
+0.2
+0.0
N.D.
-0.8
+0.6
carbon source
casaminos 1 mg/mL (C)
-0.0
+0.2
N.D.
-0.5
+0.7
stress
7H9 with Hygromycin B 0.0095 mM
+0.0
-0.2
N.D.
+1.0
-0.4
stress
7H9 with Rifampicin 0.00045 ug/mL
-0.1
+0.4
N.D.
-0.4
+1.0
stress
7H9 with Levofloxacin 0.3 ug/mL
+0.1
+0.0
N.D.
+1.0
-0.3
carbon source
Stearic 100 uM (C)
+0.0
-0.2
N.D.
+1.2
+0.1
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