Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv0967 and Rv0968 are separated by 56 nucleotidesRv0968 and Rv0969 are separated by 55 nucleotidesRv0969 and Rv0970 overlap by 4 nucleotidesRv0970 and Rv0971c are separated by 90 nucleotides Rv0967: Rv0967 - Copper-sensitive operon repressor CsoR, at 1,077,975 to 1,078,334 Rv0967 Rv0968: Rv0968 - Conserved protein, at 1,078,391 to 1,078,687 Rv0968 Rv0969: Rv0969 - Probable metal cation transporter P-type ATPase CtpV, at 1,078,743 to 1,081,055 Rv0969 Rv0970: Rv0970 - Probable conserved integral membrane protein, at 1,081,052 to 1,081,684 Rv0970 Rv0971c: Rv0971c - Probable enoyl-CoA hydratase EchA7 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase), at 1,081,775 to 1,082,584 Rv0971c
Group Condition Rv0967 Rv0968 Rv0969 Rv0970 Rv0971c
stress 7H9 with Clarithromycin 0.967 ug/mL N.D. -0.2 -0.0 +0.0 -1.0
carbon source Palmitic 100 uM (C) N.D. -0.4 -0.4 -0.0 -0.4
stress 7H9 with Rifampicin 0.014 ug/mL N.D. -0.2 -0.1 -0.3 -0.6
stress 7H9 with Moxifloxacin 0.121 ug/mL N.D. -0.6 -0.2 -0.1 -0.2
stress 7H9 with Clofazimine 0.45 ug/mL N.D. -0.2 +0.0 -0.1 -0.9
stress 7H9 with Rifampicin 0.014 ug/mL N.D. +0.2 -0.4 -0.6 -0.3
carbon source L-Asparagine (C) N.D. +0.1 -0.1 -0.2 -0.6
stress 7H9 with Delamanid 0.236 ug/mL N.D. +0.0 +0.1 +0.0 -1.0
stress 7H9 with Sulfamethizole 0.026 mM N.D. -0.0 -0.1 +0.2 -0.8
stress 7H9 with Delamanid 0.236 ug/mL N.D. +0.4 +0.1 +0.0 -1.1
nitrogen source L-Aspartic Acid 10 mM (N) N.D. +0.2 +0.0 -0.2 -0.6
carbon source butyrate 10 mM (C) N.D. +0.2 -0.2 +0.0 -0.6
carbon source L-Lactate 10 mM (C) N.D. +0.5 -0.0 -0.2 -0.8
carbon source D-Trehalose 10 mM (C) N.D. +0.6 +0.1 -0.2 -0.8
nitrogen source Glycine 10 mM (N) N.D. +0.3 +0.1 -0.1 -0.7
no stress control no stress control N.D. +0.0 +0.4 +0.2 -0.7
stress 7H9 with para-aminosalicylic 0.086 ug/mL N.D. +0.6 +0.0 -0.1 -0.6
nitrogen source Glycine 10 mM (N) N.D. +0.6 -0.0 -0.0 -0.6
carbon source L-Lactate 10 mM (C) N.D. +0.7 +0.0 +0.0 -0.8
carbon source casaminos 1 mg/mL (C) N.D. +0.6 +0.1 +0.1 -0.8
nitrogen source L-Alanine 10 mM (N) N.D. +0.5 +0.1 -0.3 -0.3
carbon source D-Lactate 10 mM (C) N.D. +0.6 +0.0 +0.0 -0.6
carbon source D,L-Malic Acid 10 mM (C) N.D. +0.8 -0.0 -0.1 -0.6
carbon source Valeric 10 mM (C) N.D. +0.6 -0.1 +0.1 -0.4
no stress control no stress control N.D. -0.8 -0.1 +0.3 +0.6
stress 7H9 with Isoniazid 0.025 ug/mL N.D. -0.5 -0.2 +0.2 +0.7
carbon source D-Lactate 10 mM (C) N.D. +0.7 +0.2 +0.0 -0.6
carbon source D,L-Malic Acid 10 mM (C) N.D. +0.9 +0.2 +0.0 -0.6
nitrogen source L-Glutamic 10 mM (N) N.D. +0.8 +0.1 -0.2 -0.3
stress 7H9 with Isoniazid 0.025 ug/mL N.D. +0.9 +0.2 +0.3 +0.8
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