Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv0932c and Rv0933 are separated by 215 nucleotidesRv0933 and Rv0934 are separated by 20 nucleotidesRv0934 and Rv0935 are separated by 59 nucleotidesRv0935 and Rv0936 are separated by 1 nucleotides Rv0932c: Rv0932c - Periplasmic phosphate-binding lipoprotein PstS2 (PBP-2) (PstS2), at 1,039,936 to 1,041,048 Rv0932c Rv0933: Rv0933 - Phosphate-transport ATP-binding protein ABC transporter PstB, at 1,041,264 to 1,042,094 Rv0933 Rv0934: Rv0934 - Periplasmic phosphate-binding lipoprotein PstS1 (PBP-1) (PstS1), at 1,042,115 to 1,043,239 Rv0934 Rv0935: Rv0935 - Phosphate-transport integral membrane ABC transporter PstC1, at 1,043,299 to 1,044,315 Rv0935 Rv0936: Rv0936 - Phosphate-transport integral membrane ABC transporter PstA2, at 1,044,317 to 1,045,222 Rv0936
Group Condition Rv0932c Rv0933 Rv0934 Rv0935 Rv0936
stress 7H9 with Isoniazid 0.025 ug/mL -0.2 -0.5 -0.5 -0.3 -0.9
nitrogen source Urea 10mM (N) +0.1 -2.5 +0.1 +0.1 -0.1
no stress control no stress control -0.2 -2.4 +0.1 +0.0 +0.1
no stress control no stress control +0.0 -2.1 +0.0 +0.1 +0.3
stress 7H9 with hypochlorite 0.4 vol% +0.1 -1.1 -0.3 -0.1 -0.0
nitrogen source L-Glutamic 10 mM (N) -0.0 -1.6 +0.4 +0.1 -0.4
carbon source oleate 200uM (C) +0.1 -1.1 -0.3 -0.1 +0.2
stress 7H9 with Geneticin G418 0.35 mM +0.1 -1.2 +0.1 -0.0 -0.1
stress 7H9 with Ethionamide 0.1 ug/mL -0.1 -1.0 +0.3 +0.3 -0.6
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 +0.2 -1.0 +0.1 -0.5 +0.2
stress 7H9 with Nickel (II) chloride 0.6 mM -0.0 -1.1 +0.4 -0.0 +0.1
nitrogen source L-Asparagine 10 mM (N) +0.2 -0.8 +0.3 +0.2 -0.1
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 +0.2 -1.1 +0.4 -0.1 +0.3
pH 7H9 pH 5.5 +0.1 -0.8 +0.3 +0.4 +0.1
stress 7H9 with Levofloxacin 0.3 ug/mL +0.2 +0.8 -0.3 -0.1 -0.5
stress 7H9 with Hygromycin B 0.0095 mM +0.2 -0.6 +0.6 +0.1 -0.0
no stress control no stress control +0.0 +1.2 -0.2 -0.1 -0.2
stress 7H9 with Plumbagin 0.01 mM -0.2 +0.9 -0.3 +0.3 +0.2
stress 7H9 with Norfloxacin 0.125 mM +0.4 +0.9 -0.2 -0.4 +0.2
stress 7H9 with Dibucaine 0.21 mM +0.1 +0.7 -0.4 +0.2 +0.3
stress 7H9 with copper (II) chloride 0.08 mM -0.1 +0.8 -0.4 +0.3 +0.4
nitrogen source Glycine 10 mM (N) +0.0 +1.1 +0.5 -0.1 -0.3
nitrogen source L-Aspartic Acid 10 mM (N) +0.0 +1.2 +0.1 -0.1 +0.2
stress 7H9 with Amikacin di2 ug/mL +0.2 +1.4 -0.0 -0.2 -0.0
stress 7H9 with Norfloxacin 0.125 mM +0.4 +0.3 +0.2 -0.0 +0.5
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM +0.2 +1.2 +0.2 -0.1 +0.1
carbon source L-Lactate 10 mM (C) +0.0 +0.5 +0.4 +0.3 +0.3
stress 7H9 with Sisomicin 0.07 mM +0.5 +0.9 +0.1 +0.1 +0.4
pH pH 4.5 +0.1 +2.0 +2.1 +2.5 +2.2
pH pH 4.5 +0.2 +2.0 +2.6 +2.6 +2.2
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