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Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv0930 and Rv0931c overlap by 6 nucleotides
Rv0931c and Rv0932c are separated by 21 nucleotides
Rv0932c and Rv0933 are separated by 215 nucleotides
Rv0933 and Rv0934 are separated by 20 nucleotides
Rv0930: Rv0930 - Probable phosphate-transport integral membrane ABC transporter PstA1, at 1,036,999 to 1,037,925
Rv0930
Rv0931c: Rv0931c - Transmembrane serine/threonine-protein kinase D PknD (protein kinase D) (STPK D), at 1,037,920 to 1,039,914
Rv0931c
Rv0932c: Rv0932c - Periplasmic phosphate-binding lipoprotein PstS2 (PBP-2) (PstS2), at 1,039,936 to 1,041,048
Rv0932c
Rv0933: Rv0933 - Phosphate-transport ATP-binding protein ABC transporter PstB, at 1,041,264 to 1,042,094
Rv0933
Rv0934: Rv0934 - Periplasmic phosphate-binding lipoprotein PstS1 (PBP-1) (PstS1), at 1,042,115 to 1,043,239
Rv0934
Group
Condition
Rv0930
Rv0931c
Rv0932c
Rv0933
Rv0934
stress
7H9 with Isoniazid 0.025 ug/mL
-2.3
-0.2
-0.2
-0.5
-0.5
stress
7H9 with Moxifloxacin 0.121 ug/mL
-3.2
+0.1
+0.1
-0.4
-0.1
stress
7H9 with Meropenem 9.6 ug/mL
-2.9
-0.2
+0.0
-0.1
+0.1
stress
7H9 with Hygromycin B 0.0095 mM
-2.3
-0.0
-0.0
-0.8
+0.2
nitrogen source
L-Glutamic 10 mM (N)
-1.7
+0.1
+0.0
-1.5
+0.4
stress
7H9 with Bedaquiline 0.15 ug/mL
-2.7
+0.1
+0.1
-0.5
+0.2
stress
7H9 with Rifampicin 0.00045 ug/mL
-2.8
-0.0
+0.1
-0.2
+0.0
stress
7H9 with Rifampicin 0.014 ug/mL
-3.0
+0.1
+0.3
-0.2
+0.1
stress
7H9 with Rifampicin 0.00045 ug/mL
-2.8
-0.0
+0.0
+0.1
+0.1
stress
7H9 with Bedaquiline 0.15 ug/mL
-2.7
+0.1
+0.1
+0.1
-0.2
stress
7H9 with Rifampicin 0.014 ug/mL
-2.6
+0.1
+0.1
-0.4
+0.3
carbon source
Stearic 100 uM (C)
-1.9
-0.1
-0.0
-0.4
+0.2
stress
7H9 with Streptomycin 0.178 ug/mL
-1.9
+0.0
-0.1
-0.4
+0.3
stress
7H9 with Streptomycin 0.178 ug/mL
-2.5
+0.1
+0.1
+0.2
+0.0
stress
7H9 with Clarithromycin 0.967 ug/mL
-2.8
+0.0
-0.1
+0.7
+0.1
stress
7H9 with Clarithromycin 0.967 ug/mL
-3.1
-0.1
+0.2
+0.6
+0.2
stress
7H9 with Meropenem 9.6 ug/mL
-2.6
+0.1
+0.0
-0.1
+0.6
nitrogen source
L-Asparagine 10 mM (N)
-1.7
+0.1
+0.2
-0.8
+0.3
carbon source
Stearic 100 uM (C)
-2.0
-0.0
-0.1
-0.2
+0.3
stress
7H9 with Hygromycin B 0.0095 mM
-2.0
+0.1
+0.2
-0.6
+0.6
stress
7H9 with Moxifloxacin 0.121 ug/mL
-2.7
-0.0
+0.2
+0.6
+0.2
nitrogen source
L-Asparagine 10 mM (N)
-2.7
+0.1
+0.1
+0.8
+0.1
nitrogen source
L-Aspartic Acid 10 mM (N)
-1.9
+0.1
+0.3
+0.2
+0.2
nitrogen source
L-Aspartic Acid 10 mM (N)
-2.3
+0.0
+0.0
+1.2
+0.1
nitrogen source
L-Glutamine 10 mM (N)
-2.1
+0.1
+0.1
+0.5
+0.4
nitrogen source
L-Glutamic 10 mM (N)
-1.8
+0.1
+0.1
+0.5
+0.2
nitrogen source
L-Alanine 10 mM (N)
-1.8
+0.1
+0.1
+0.5
+0.3
carbon source
L-Lactate 10 mM (C)
-1.6
-0.0
+0.0
+0.5
+0.4
nitrogen source
L-Glutamine 10 mM (N)
-1.7
+0.0
+0.1
+0.6
+0.4
nitrogen source
Glycine 10 mM (N)
-1.5
+0.0
+0.0
+1.1
+0.5
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