Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv0905 and Rv0906 are separated by 5 nucleotidesRv0906 and Rv0907 are separated by 73 nucleotidesRv0907 and Rv0908 overlap by 4 nucleotidesRv0908 and Rv0909 are separated by 556 nucleotides Rv0905: Rv0905 - Possible enoyl-CoA hydratase EchA6 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase), at 1,008,207 to 1,008,938 Rv0905 Rv0906: Rv0906 - Conserved protein, at 1,008,944 to 1,010,062 Rv0906 Rv0907: Rv0907 - Conserved protein, at 1,010,136 to 1,011,734 Rv0907 Rv0908: Rv0908 - Probable metal cation transporter ATPase P-type CtpE, at 1,011,731 to 1,014,124 Rv0908 Rv0909: Rv0909 - Conserved hypothetical protein, at 1,014,681 to 1,014,860 Rv0909
Group Condition Rv0905 Rv0906 Rv0907 Rv0908 Rv0909
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -1.8 +0.0 -0.1 +0.2 N.D.
stress 7H9 with Ethionamide 0.1 ug/mL -0.7 -0.5 +0.0 -0.2 N.D.
stress 7H9 with Sisomicin 0.07 mM -0.7 -0.2 -0.1 -0.3 N.D.
stress 7H9 with EDTA (disodium salt) 0.2 mM -0.6 +0.1 -0.6 -0.1 N.D.
stress 7H9 with Bedaquiline 0.15 ug/mL -0.8 +0.1 -0.3 -0.1 N.D.
stress 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM -0.8 -0.3 -0.1 +0.1 N.D.
stress 7H9 with copper (II) chloride 0.08 mM -0.5 +0.0 -0.8 +0.1 N.D.
nitrogen source L-Glutamine 10 mM (N) -0.9 -0.2 -0.1 +0.2 N.D.
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -1.3 -0.0 +0.3 -0.1 N.D.
stress 7H9 with Benzethonium chloride 0.068 mM -0.4 +0.1 -0.6 +0.3 N.D.
stress 7H9 with nitrite 5 mM -0.8 +0.2 -0.2 +0.2 N.D.
stress 7H9 with Cumene hydroperoxide 0.05 mM -0.5 -0.3 +0.4 +0.2 N.D.
no stress control no stress control +0.7 -0.1 -0.7 +0.0 N.D.
nitrogen source Urea 10mM (N) -0.5 -0.4 +0.3 +0.5 N.D.
stress 7H9 with Amikacin di2 ug/mL -0.3 -0.4 +0.4 +0.3 N.D.
nitrogen source L-Valine 10 mM (N) +0.4 -0.6 +0.3 -0.1 N.D.
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.6 -0.1 +0.6 +0.3 N.D.
nitrogen source Urea 10mM (N) -0.2 -0.2 +0.5 +0.4 N.D.
stress 7H9 with Nickel (II) chloride 0.6 mM +1.1 -0.6 +0.2 -0.2 N.D.
carbon source D-Lactate 10 mM (C) +0.6 -0.2 +0.3 -0.1 N.D.
stress 7H9 with Ethionamide 0.1 ug/mL +0.4 -0.3 +0.4 +0.2 N.D.
stress 7H9 with Meropenem 9.6 ug/mL -0.2 -0.1 +0.7 +0.4 N.D.
stress 7H9 with Plumbagin 0.01 mM +0.7 +0.2 -0.4 +0.3 N.D.
carbon source Palmitic 100 uM (C) +0.4 -0.2 +0.2 +0.5 N.D.
nitrogen source L-Asparagine 10 mM (N) +0.4 -0.2 +0.2 +0.5 N.D.
carbon source cholesterol 100uM (C) -0.8 -0.1 +0.6 +1.2 N.D.
nitrogen source L-Glutamine 10 mM (N) +0.2 -0.1 +0.4 +0.6 N.D.
stress 7H9 with Dimethyl Sulfoxide 1 vol% +0.4 -0.1 +0.5 +0.6 N.D.
carbon source heptadecanoic 250 uM (C) +0.9 +0.2 +0.1 +0.2 N.D.
carbon source cholesterol 100uM (C) -0.6 +0.1 +0.9 +1.4 N.D.
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