Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv0818 and Rv0819 overlap by 4 nucleotidesRv0819 and Rv0820 are separated by 42 nucleotidesRv0820 and Rv0821c are separated by 55 nucleotidesRv0821c and Rv0822c are separated by 57 nucleotides Rv0818: Rv0818 - Transcriptional regulatory protein, at 910,972 to 911,739 Rv0818 Rv0819: Rv0819 - GCN5-related N-acetyltransferase, MshD, at 911,736 to 912,683 Rv0819 Rv0820: Rv0820 - Probable phosphate-transport ATP-binding protein ABC transporter PhoT, at 912,726 to 913,502 Rv0820 Rv0821c: Rv0821c - Probable phosphate-transport system transcriptional regulatory protein PhoY2, at 913,558 to 914,199 Rv0821c Rv0822c: Rv0822c - Conserved protein, at 914,257 to 916,311 Rv0822c
Group Condition Rv0818 Rv0819 Rv0820 Rv0821c Rv0822c
stress 7H9 with Meropenem 9.6 ug/mL -1.1 -3.8 -2.2 -1.3 -0.2
stress 7H9 with Meropenem 9.6 ug/mL -0.8 -3.2 -1.6 -0.5 -0.1
nitrogen source L-Asparagine 10 mM (N) -0.8 -2.3 -1.7 -0.6 -0.2
stress 7H9 with Bedaquiline 0.15 ug/mL -0.7 -2.3 -2.8 +0.1 +0.1
stress 7H9 with Bedaquiline 0.15 ug/mL -0.4 -2.3 -2.8 -0.0 -0.0
stress 7H9 with Clofazimine 0.45 ug/mL -0.8 -1.9 -2.3 -0.4 -0.1
stress 7H9 with Rifampicin 0.00045 ug/mL -0.8 -2.0 -2.7 +0.5 -0.1
stress 7H9 with Rifampicin 0.014 ug/mL -0.7 -1.8 -2.7 +0.1 -0.1
nitrogen source L-Serine 10 mM (N) -0.6 -2.3 -1.3 -0.7 -0.1
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.6 -3.5 -1.3 +0.2 +0.3
carbon source Stearic 100 uM (C) -0.3 -2.3 -1.7 -0.5 -0.1
carbon source Stearic 100 uM (C) -0.4 -2.1 -1.8 -0.5 -0.1
stress 7H9 with Hygromycin B 0.0095 mM -0.8 -2.2 -1.8 +0.1 -0.1
stress 7H9 with Rifampicin 0.00045 ug/mL -0.7 -1.8 -2.6 +0.3 +0.1
stress 7H9 with para-aminosalicylic 0.086 ug/mL -0.8 -2.8 -1.1 -0.1 -0.0
nitrogen source L-Aspartic Acid 10 mM (N) -0.5 -1.6 -1.8 -0.8 -0.1
nitrogen source L-Aspartic Acid 10 mM (N) -0.8 -1.7 -1.4 -0.5 -0.2
nitrogen source Glycine 10 mM (N) -0.5 -2.1 -1.2 -0.6 -0.3
nitrogen source Glycine 10 mM (N) -0.5 -1.7 -1.5 -0.6 -0.3
nitrogen source L-Glutamic 10 mM (N) -0.7 -1.9 -1.1 -0.9 -0.1
stress 7H9 with Hygromycin B 0.0095 mM -0.8 -2.5 -1.6 +0.4 -0.1
stress 7H9 with Rifampicin 0.014 ug/mL -0.7 -1.7 -2.3 +0.3 -0.0
nitrogen source L-Alanine 10 mM (N) -0.5 -2.3 -1.5 +0.0 -0.2
nitrogen source L-Glutamine 10 mM (N) -0.4 -1.4 -1.8 -0.9 -0.1
carbon source butyrate 10 mM (C) -0.4 -1.8 -1.2 -1.0 -0.1
stress 7H9 with Clarithromycin 0.967 ug/mL -0.5 -2.3 -1.8 +0.1 +0.0
stress 7H9 with Clarithromycin 0.967 ug/mL -0.5 -1.8 -1.7 -0.4 +0.0
stress 7H9 with Streptomycin 0.178 ug/mL -0.6 -3.0 -1.0 +0.2 +0.1
stress 7H9 with Clofazimine 0.45 ug/mL -0.7 -1.5 -2.1 +0.1 -0.0
stress 7H9 with Clofazimine 0.072 ug/mL -0.7 -1.4 -1.9 +0.3 -0.2
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