Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv0798c and Rv0799c overlap by 4 nucleotidesRv0799c and Rv0800 are separated by 44 nucleotidesRv0800 and Rv0801 are separated by 11 nucleotidesRv0801 and Rv0802c overlap by 7 nucleotides Rv0798c: Rv0798c - 29 KDa antigen CFP29, at 891,472 to 892,269 Rv0798c Rv0799c: Rv0799c - Conserved protein, at 892,266 to 893,273 Rv0799c Rv0800: Rv0800 - Probable aminopeptidase PepC, at 893,318 to 894,619 Rv0800 Rv0801: Rv0801 - Conserved protein, at 894,631 to 894,978 Rv0801 Rv0802c: Rv0802c - Possible succinyltransferase in the GCN5-related N-acetyltransferase family, at 894,972 to 895,628 Rv0802c
Group Condition Rv0798c Rv0799c Rv0800 Rv0801 Rv0802c
stress 7H9 with para-aminosalicylic 0.086 ug/mL -0.7 -0.3 -0.1 N.D. -0.3
no stress control no stress control -0.7 -0.6 -0.0 N.D. -0.0
pH pH 5.5 -0.5 -0.0 -0.0 N.D. -0.7
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -0.8 -0.1 -0.2 N.D. -0.2
stress 7H9 with nitrite 3 mM; pH 5.5 -0.4 -0.0 -0.3 N.D. -0.3
stress 7H9 with Levofloxacin 0.3 ug/mL -0.4 -0.3 -0.0 N.D. -0.3
stress 7H9 with Ethionamide 0.1 ug/mL -0.5 -0.3 +0.1 N.D. -0.3
stress 7H9 with Phenazine ethosulfate 0.0137 mM -0.4 -0.5 +0.2 N.D. +0.1
stress 7H9 with Cetrimonium bromide 0.015 vol% +0.3 -0.4 +0.0 N.D. -0.4
stress 7H9 with Ethambutol 0.75 ug/mL -0.2 -0.2 -0.3 N.D. +0.3
no stress control no stress control +0.4 +0.1 -0.3 N.D. -0.5
pH pH 4.5 -0.6 +0.1 +0.3 N.D. +0.0
no stress control no stress control +0.4 +0.0 +0.1 N.D. -0.6
stress 7H9 with Linezolid 0.44 ug/mL +0.2 +0.2 +0.2 N.D. -0.6
carbon source cholesterol 100uM (C) +0.3 -0.5 -0.0 N.D. +0.3
nitrogen source L-Aspartic Acid 10 mM (N) +0.3 +0.2 +0.2 N.D. -0.5
carbon source butyrate 10 mM (C) -0.5 +0.2 +0.2 N.D. +0.3
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 +0.6 +0.1 -0.1 N.D. -0.4
stress 7H9 with Chlorpromazine 0.054 mM +1.0 -0.1 -0.1 N.D. -0.6
no stress control no stress control +0.5 -0.3 +0.2 N.D. -0.2
stress 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM +0.5 +0.2 +0.1 N.D. -0.5
stress 7H9 with Spectinomycin 0.029 mM +0.4 -0.2 -0.1 N.D. +0.4
stress 7H9 with Geneticin G418 0.35 mM +0.2 -0.3 +0.7 N.D. -0.1
pH 7H9 pH 5.5 +0.4 +0.3 -0.5 N.D. +0.3
stress 7H9 with nitrite 5 mM +0.3 -0.2 +0.8 N.D. -0.2
stress 7H9 with Spectinomycin 0.029 mM +0.6 +0.1 +0.3 N.D. -0.4
stress 7H9 with Sisomicin 0.07 mM +0.5 -0.2 +0.4 N.D. +0.2
stress 7H9 with Sisomicin 0.07 mM +0.3 +0.2 +0.1 N.D. +0.5
nitrogen source L-Aspartic Acid 10 mM (N) +0.7 +0.1 +0.2 N.D. +0.2
stress 7H9 with nitrite 2.5 mM +0.7 +0.2 +0.6 N.D. +0.0
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