Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv0782 and Rv0783c are separated by 427 nucleotidesRv0783c and Rv0784 are separated by 197 nucleotidesRv0784 and Rv0785 are separated by 15 nucleotidesRv0785 and Rv0786c are separated by 34 nucleotides Rv0782: Rv0782 - Probable protease II PtrBb [second part] (oligopeptidase B), at 874,732 to 876,390 Rv0782 Rv0783c: Rv0783c - Possible multidrug resistance integral membrane efflux protein EmrB, at 876,818 to 878,440 Rv0783c Rv0784: Rv0784 - Conserved hypothetical protein, at 878,638 to 879,324 Rv0784 Rv0785: Rv0785 - Conserved protein, at 879,340 to 881,040 Rv0785 Rv0786c: Rv0786c - Conserved protein, at 881,075 to 881,464 Rv0786c
Group Condition Rv0782 Rv0783c Rv0784 Rv0785 Rv0786c
stress 7H9 with Sulfamethizole 0.026 mM -0.6 -0.2 N.D. -0.1 -0.7
stress 7H9 with Nickel (II) chloride 0.6 mM -0.9 -0.1 N.D. -0.0 -0.5
stress 7H9 with Amikacin di2 ug/mL -0.7 -0.1 N.D. -0.2 -0.5
carbon source cholesterol 100uM (C) -1.0 +0.1 N.D. -0.1 -0.3
stress 7H9 with Sisomicin 0.07 mM -0.6 -0.7 N.D. -0.1 +0.1
stress 7H9 with Rifampicin 0.00045 ug/mL -0.9 +0.3 N.D. -0.3 -0.3
pH 7H9 pH 5.5 -0.5 -0.2 N.D. +0.3 -0.5
stress 7H9 with EDTA (disodium salt) 0.2 mM -0.3 -0.9 N.D. +0.1 +0.3
no stress control no stress control -0.7 +0.4 N.D. +0.0 -0.5
stress 7H9 with Bedaquiline 0.15 ug/mL -0.7 +0.4 N.D. +0.1 -0.5
stress 7H9 with Lomefloxacin 0.0035 mM -0.7 -0.4 N.D. +0.3 +0.2
carbon source oleate 200uM (C) -0.7 +0.6 N.D. -0.0 -0.5
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 -0.5 -0.7 N.D. +0.2 +0.4
stress 7H9 with Amikacin di2 ug/mL -0.2 +0.5 N.D. -0.2 -0.6
carbon source Valeric 10 mM (C) -0.8 +0.3 N.D. -0.1 +0.3
stress 7H9 with Dimethyl Sulfoxide 1 vol% -0.4 +0.5 N.D. +0.0 -0.5
no stress control no stress control +0.4 +0.3 N.D. -0.5 -0.5
stress 7H9 with Dimethyl Sulfoxide 1 vol% -0.4 +0.7 N.D. -0.0 -0.5
stress 7H9 with Norfloxacin 0.125 mM -0.3 -0.5 N.D. -0.1 +0.8
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -0.3 +0.7 N.D. +0.0 -0.4
no stress control no stress control +0.8 +0.1 N.D. -0.0 -0.8
stress 7H9 with Isoniazid 0.025 ug/mL +2.0 -0.4 N.D. -0.2 -1.2
stress 7H9 with nitrite 2.5 mM -0.8 +0.8 N.D. -0.1 +0.5
stress 7H9 with Spectinomycin 0.029 mM +0.6 +0.4 N.D. -0.2 -0.4
stress 7H9 with Isoniazid 0.025 ug/mL +1.1 +0.3 N.D. -0.1 -0.2
stress 7H9 with Ethionamide 0.1 ug/mL +1.2 +0.1 N.D. -0.1 -0.2
nitrogen source L-Asparagine 10 mM (N) +0.1 +0.9 N.D. -0.2 +0.3
nitrogen source L-Glutamine 10 mM (N) +0.2 +1.3 N.D. -0.1 +0.3
nitrogen source L-Glutamic 10 mM (N) +0.1 +1.7 N.D. -0.0 +0.4
nitrogen source L-Glutamic 10 mM (N) +0.3 +1.5 N.D. -0.0 +0.7
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