Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv0654 and Rv0655 are separated by 11 nucleotidesRv0655 and Rv0656c are separated by 387 nucleotidesRv0656c and Rv0657c are separated by 94 nucleotidesRv0657c and Rv0658c are separated by 75 nucleotides Rv0654: Rv0654 - Probable dioxygenase, at 750,000 to 751,505 Rv0654 Rv0655: Rv0655 - Possible ribonucleotide-transport ATP-binding protein ABC transporter Mkl, at 751,517 to 752,596 Rv0655 Rv0656c: Rv0656c - Possible toxin VapC6, at 752,984 to 753,367 Rv0656c Rv0657c: Rv0657c - Possible antitoxin VapB6, at 753,462 to 753,617 Rv0657c Rv0658c: Rv0658c - Probable conserved integral membrane protein, at 753,693 to 754,409 Rv0658c
Group Condition Rv0654 Rv0655 Rv0656c Rv0657c Rv0658c
carbon source heptadecanoic 250 uM (C) -0.1 -2.5 -0.3 N.D. -0.1
pH 7H9 pH 5.5 -0.1 -1.1 -0.1 N.D. -1.1
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 -0.1 -1.3 -0.2 N.D. -0.7
stress 7H9 with Nickel (II) chloride 0.6 mM -0.1 -1.0 -0.7 N.D. -0.5
stress 7H9 with Antimycin A 0.0186 mM +0.1 -1.6 -0.2 N.D. -0.5
no stress control no stress control +0.0 -1.4 +0.2 N.D. -1.0
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -0.0 -1.5 +0.1 N.D. -0.7
stress 7H9 with Amikacin di2 ug/mL +0.0 -1.3 -0.4 N.D. -0.2
no stress control no stress control -0.1 -1.3 -0.2 N.D. -0.4
stress 7H9 with Meropenem 9.6 ug/mL +0.1 -1.1 -0.1 N.D. -0.7
carbon source Stearic 100 uM (C) -0.0 -1.9 +0.3 N.D. -0.2
stress 7H9 with Meropenem 9.6 ug/mL -0.0 -1.1 -0.2 N.D. -0.5
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -0.0 -1.8 +0.3 N.D. -0.2
carbon source Stearic 100 uM (C) +0.0 -1.8 +0.1 N.D. +0.0
carbon source cholesterol 100uM (C) -0.1 -1.8 +0.3 N.D. -0.1
stress 7H9 with Phenazine ethosulfate 0.0137 mM +0.1 -2.0 +0.3 N.D. -0.1
no stress control no stress control +0.0 -0.9 -0.0 N.D. -0.9
carbon source heptadecanoic 250 uM (C) -0.0 -1.9 +0.0 N.D. +0.3
stress 7H9 with Amikacin di2 ug/mL -0.1 -1.1 +0.3 N.D. -0.4
carbon source cholesterol 100uM (C) -0.1 -1.7 +0.4 N.D. +0.2
stress 7H9 with Cumene hydroperoxide 0.05 mM +0.0 -0.8 +0.3 N.D. -0.7
no stress control no stress control -0.0 -0.9 +0.4 N.D. -0.7
stress 7H9 with Hydrogen peroxide 3.97 mM -0.0 -1.4 +0.0 N.D. +0.3
carbon source Glycerol (C) +0.0 -1.4 +0.0 N.D. +0.3
stress 7H9 with methylglyoxal 1.2 mM +0.1 -1.6 -0.1 N.D. +0.7
stress 7H9 with methylglyoxal 1.2 mM -0.2 -1.2 -0.0 N.D. +0.8
carbon source propionate (C) +0.1 -1.2 +0.2 N.D. +0.4
carbon source oleate 200uM (C) -0.0 +0.8 -0.3 N.D. -0.9
stress 7H9 with Zinc Pyrithione 0.00072 mM -0.1 -1.3 +0.2 N.D. +0.9
stress 7H9 with Econazole nitrate salt 0.0082 mM +0.1 -0.6 +0.1 N.D. +1.0
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