Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv0623 and Rv0624 overlap by 1 nucleotidesRv0624 and Rv0625c are separated by 93 nucleotidesRv0625c and Rv0626 are separated by 131 nucleotidesRv0626 and Rv0627 overlap by 4 nucleotides Rv0623: Rv0623 - Possible antitoxin VapB30, at 716,410 to 716,664 Rv0623 Rv0624: Rv0624 - Possible toxin VapC30. Contains PIN domain., at 716,664 to 717,059 Rv0624 Rv0625c: Rv0625c - Probable conserved transmembrane protein, at 717,153 to 717,893 Rv0625c Rv0626: Rv0626 - Possible antitoxin VapB5, at 718,025 to 718,285 Rv0626 Rv0627: Rv0627 - Possible toxin VapC5, at 718,282 to 718,689 Rv0627
Group Condition Rv0623 Rv0624 Rv0625c Rv0626 Rv0627
no stress control no stress control -0.7 -0.1 -0.6 N.D. N.D.
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM -0.4 -0.3 -0.6 N.D. N.D.
stress 7H9 with Ethionamide 0.1 ug/mL -0.6 -0.0 -0.7 N.D. N.D.
pH 7H9 pH 5.5 -0.6 -0.3 -0.3 N.D. N.D.
no stress control no stress control -0.3 +0.1 -1.0 N.D. N.D.
stress 7H9 with Isoniazid 0.025 ug/mL -0.3 -0.0 -0.8 N.D. N.D.
stress 7H9 with Cumene hydroperoxide 0.05 mM -0.6 -0.2 -0.3 N.D. N.D.
no stress control no stress control -0.3 -0.2 -0.5 N.D. N.D.
stress 7H9 with Tetrazolium violet 0.065 mM -0.3 -0.4 -0.3 N.D. N.D.
stress 7H9 with Dicloxacillin 0.0069 mM -0.5 -0.4 -0.0 N.D. N.D.
no stress control no stress control -0.6 -0.0 -0.3 N.D. N.D.
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 -0.2 -0.2 -0.5 N.D. N.D.
stress 7H9 with 2,4-Dinitrophenol 0.1503 mM -0.5 -0.3 -0.1 N.D. N.D.
no stress control no stress control -0.5 +0.0 -0.4 N.D. N.D.
stress 7H9 with Tetracycline 0.0058 mM +0.1 -0.8 -0.2 N.D. N.D.
stress 7H9 with Ofloxacin 0.8 ug/mL -0.4 +0.1 -0.4 N.D. N.D.
stress 7H9 with Norfloxacin 0.125 mM +0.2 -0.6 -0.3 N.D. N.D.
stress 7H9 with Ofloxacin 0.8 ug/mL +0.0 +0.2 -0.7 N.D. N.D.
stress 7H9 with Zinc Pyrithione 0.00072 mM +0.2 -0.5 -0.2 N.D. N.D.
stress 7H9 with Levofloxacin 0.3 ug/mL -0.5 +0.3 -0.3 N.D. N.D.
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.4 +0.3 -0.4 N.D. N.D.
stress 7H9 with Ethionamide 0.1 ug/mL -0.2 +0.2 -0.4 N.D. N.D.
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.5 +0.5 -0.3 N.D. N.D.
stress 7H9 with Hydrogen peroxide 3.97 mM +0.3 -0.4 -0.2 N.D. N.D.
stress 7H9 with Linezolid 0.3 ug/mL +0.3 -0.5 -0.0 N.D. N.D.
stress 7H9 with nitrite 5 mM +0.3 -0.5 +0.1 N.D. N.D.
stress 7H9 with copper (II) chloride 0.08 mM +0.4 -0.5 -0.0 N.D. N.D.
carbon source cholesterol 100uM (C) +0.6 -0.3 -0.2 N.D. N.D.
carbon source L-Aspartic Acid (C) -0.4 +0.4 +0.2 N.D. N.D.
carbon source pyruvate (C) -0.3 +0.4 +0.3 N.D. N.D.
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