Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv0566c and GFF587 are separated by 69 nucleotidesGFF587 and Rv0567 are separated by 131 nucleotidesRv0567 and Rv0568 are separated by 109 nucleotidesRv0568 and Rv0569 are separated by 134 nucleotides Rv0566c: Rv0566c - Conserved protein, at 657,548 to 658,039 Rv0566c GFF587 - tRNA-Tyr, at 658,109 to 658,189 GFF587 Rv0567: Rv0567 - Probable methyltransferase/methylase, at 658,321 to 659,340 Rv0567 Rv0568: Rv0568 - Possible cytochrome P450 135B1 Cyp135B1, at 659,450 to 660,868 Rv0568 Rv0569: Rv0569 - Conserved protein, at 661,003 to 661,269 Rv0569
Group Condition Rv0566c GFF587 Rv0567 Rv0568 Rv0569
stress 7H9 with Nickel (II) chloride 0.6 mM -0.5 N.D. -0.2 -0.6 -1.0
no stress control no stress control -0.1 N.D. -0.1 -0.2 -1.2
stress 7H9 with Meropenem 9.6 ug/mL -0.9 N.D. +0.1 -0.1 -0.7
stress 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM -0.4 N.D. +0.1 -0.1 -1.2
carbon source butyrate 10 mM (C) -0.5 N.D. +0.2 +0.1 -1.2
no stress control no stress control -0.8 N.D. -0.1 -0.2 -0.3
stress 7H9 with Nickel (II) chloride 0.6 mM -0.5 N.D. -0.1 -0.8 -0.0
stress 7H9 with Ethionamide 0.1 ug/mL -0.3 N.D. +0.1 +0.1 -1.0
stress 7H9 with Streptomycin 0.178 ug/mL -0.4 N.D. -0.2 +0.3 -0.8
stress 7H9 with Erythromycin 0.016 mM -0.5 N.D. +0.3 +0.2 -1.1
stress 7H9 with Rifampicin 0.014 ug/mL -0.8 N.D. -0.4 +0.0 +0.2
stress 7H9 with Levofloxacin 0.3 ug/mL -0.3 N.D. +0.3 +0.1 -0.8
no stress control no stress control -0.4 N.D. +0.3 -0.1 -0.7
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -0.6 N.D. +0.5 +0.2 -0.7
stress 7H9 with Irgasan 0.065 mM -0.3 N.D. +0.5 +0.0 -0.6
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -0.4 N.D. +0.5 +0.1 -0.7
stress 7H9 with Menadione 0.005 mM -1.0 N.D. +0.2 +0.0 +0.4
stress 7H9 with nitrite 1.5 mM; pH 5.5 -0.5 N.D. +0.5 +0.4 -0.6
stress 7H9 with 2,4-Dinitrophenol 0.1503 mM +0.5 N.D. +0.2 +0.0 -0.8
stress 7H9 with Amikacin di2 ug/mL -0.7 N.D. +0.3 +0.3 +0.2
stress 7H9 with Clarithromycin 0.967 ug/mL -0.8 N.D. +0.1 -0.0 +0.8
stress 7H9 with copper (II) chloride 0.08 mM -0.9 N.D. +0.2 +0.1 +0.8
no stress control no stress control -0.6 N.D. +0.2 +0.1 +0.8
stress 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM -0.5 N.D. +0.0 +0.1 +0.9
no stress control no stress control -0.4 N.D. +0.4 +0.3 +0.4
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 -0.3 N.D. +0.2 +0.2 +0.8
nitrogen source L-Alanine 10 mM (N) +0.2 N.D. -0.2 +0.1 +0.9
stress 7H9 with 8-hydroxy-nitroquinoline 0.03 mM +0.8 N.D. +0.3 +0.4 -0.3
stress 7H9 with Cloxacillin 0.0386 mM -0.2 N.D. +0.2 +0.1 +1.1
stress 7H9 with 8-hydroxy-nitroquinoline 0.03 mM +0.4 N.D. -0.1 +0.4 +0.7
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