Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv0543c and Rv0544c are separated by 59 nucleotidesRv0544c and Rv0545c overlap by 4 nucleotidesRv0545c and Rv0546c are separated by 119 nucleotidesRv0546c and Rv0547c are separated by 62 nucleotides Rv0543c: Rv0543c - Conserved protein, at 635,573 to 635,875 Rv0543c Rv0544c: Rv0544c - Possible conserved transmembrane protein, at 635,935 to 636,213 Rv0544c Rv0545c: Rv0545c - Probable low-affinity inorganic phosphate transporter integral membrane protein PitA, at 636,210 to 637,463 Rv0545c Rv0546c: Rv0546c - Conserved protein, at 637,583 to 637,969 Rv0546c Rv0547c: Rv0547c - Possible oxidoreductase, at 638,032 to 638,916 Rv0547c
Group Condition Rv0543c Rv0544c Rv0545c Rv0546c Rv0547c
nitrogen source L-Valine 10 mM (N) N.D. -2.7 -2.2 N.D. -0.4
nitrogen source L-Valine 10 mM (N) N.D. -1.3 -1.5 N.D. -0.2
carbon source Stearic 100 uM (C) N.D. +0.6 +1.1 N.D. -0.3
carbon source butyrate 10 mM (C) N.D. +0.9 +1.1 N.D. -0.2
carbon source D-Trehalose 10 mM (C) N.D. +0.7 +1.5 N.D. -0.3
nitrogen source L-Glutamine 10 mM (N) N.D. +1.0 +1.1 N.D. -0.2
carbon source Stearic 100 uM (C) N.D. +1.1 +1.0 N.D. -0.2
nitrogen source L-Glutamic 10 mM (N) N.D. +1.0 +1.1 N.D. -0.2
nitrogen source L-Aspartic Acid 10 mM (N) N.D. +1.0 +1.1 N.D. -0.2
nitrogen source L-Asparagine 10 mM (N) N.D. +1.2 +1.1 N.D. -0.4
no stress control no stress control N.D. +1.1 +1.0 N.D. -0.1
stress 7H9 with Rifampicin 0.014 ug/mL N.D. +1.0 +1.0 N.D. -0.0
nitrogen source L-Glutamic 10 mM (N) N.D. +1.2 +1.0 N.D. -0.2
stress 7H9 with Ethionamide 0.1 ug/mL N.D. +1.1 +0.9 N.D. +0.0
carbon source D-Trehalose 10 mM (C) N.D. +0.9 +1.3 N.D. -0.2
stress 7H9 with Clarithromycin 0.967 ug/mL N.D. +1.2 +0.8 N.D. +0.2
nitrogen source L-Asparagine 10 mM (N) N.D. +1.3 +1.3 N.D. -0.3
nitrogen source L-Aspartic Acid 10 mM (N) N.D. +1.2 +1.1 N.D. -0.0
nitrogen source L-Glutamine 10 mM (N) N.D. +1.4 +1.0 N.D. -0.1
stress 7H9 with Pretomanid 0.213 ug/mL N.D. +0.9 +1.4 N.D. +0.0
stress 7H9 with Ethambutol 0.75 ug/mL N.D. +1.2 +1.3 N.D. +0.1
carbon source heptadecanoic 250 uM (C) N.D. +1.5 +1.3 N.D. +0.0
stress 7H9 with Isoniazid 0.025 ug/mL N.D. +1.8 +0.9 N.D. +0.2
stress 7H9 with Pretomanid 0.213 ug/mL N.D. +1.4 +1.4 N.D. +0.2
carbon source heptadecanoic 250 uM (C) N.D. +2.1 +1.3 N.D. -0.1
stress 7H9 with Ethambutol 0.75 ug/mL N.D. +1.4 +1.6 N.D. +0.2
stress 7H9 with Ofloxacin 0.8 ug/mL N.D. +1.8 +1.5 N.D. +0.1
stress 7H9 with Ethionamide 0.1 ug/mL N.D. +1.9 +1.3 N.D. +0.2
stress 7H9 with Moxifloxacin 0.121 ug/mL N.D. +1.7 +1.5 N.D. +0.2
stress 7H9 with Ofloxacin 0.8 ug/mL N.D. +1.2 +2.1 N.D. +0.2
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