Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv0528 and Rv0529 overlap by 4 nucleotidesRv0529 and Rv0530 are separated by 41 nucleotidesRv0530 and Rv0530A overlap by 4 nucleotidesRv0530A and Rv0531 are separated by 46 nucleotides Rv0528: Rv0528 - Probable conserved transmembrane protein, at 618,305 to 619,894 Rv0528 Rv0529: Rv0529 - Possible cytochrome C-type biogenesis protein CcsA, at 619,891 to 620,865 Rv0529 Rv0530: Rv0530 - Conserved protein, at 620,907 to 622,124 Rv0530 Rv0530A: Rv0530A - Conserved protein, at 622,121 to 622,282 Rv0530A Rv0531: Rv0531 - Possible conserved membrane protein, at 622,329 to 622,646 Rv0531
Group Condition Rv0528 Rv0529 Rv0530 Rv0530A Rv0531
stress 7H9 with Sisomicin 0.07 mM N.D. N.D. -0.3 -0.3 -1.8
pH pH 4.5 N.D. N.D. -0.7 -0.5 -1.2
stress 7H9 with Nickel (II) chloride 0.6 mM N.D. N.D. +0.0 -0.7 -1.5
stress 7H9 with Lomefloxacin 0.0035 mM N.D. N.D. -0.1 -0.2 -1.7
stress 7H9 with Ethambutol 0.75 ug/mL N.D. N.D. -0.0 +0.0 -1.9
stress 7H9 with Sutezolid 0.12 ug/mL N.D. N.D. +0.3 -0.2 -2.0
stress 7H9 with Pretomanid 0.213 ug/mL N.D. N.D. -0.2 -0.1 -1.7
stress 7H9 with Hygromycin B 0.0095 mM N.D. N.D. -0.1 -0.9 -1.0
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM N.D. N.D. +0.0 -0.7 -1.2
stress 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM N.D. N.D. +0.2 +0.4 -2.4
stress 7H9 with nitrate 4 mM N.D. N.D. -0.3 -0.6 -0.9
stress 7H9 with Moxifloxacin 0.121 ug/mL N.D. N.D. +0.1 +0.2 -2.1
stress 7H9 with Hygromycin B 0.0095 mM N.D. N.D. -0.2 -0.5 -1.1
stress 7H9 with Antimycin A 0.0186 mM N.D. N.D. -0.1 -0.4 -1.2
stress 7H9 with Pretomanid 0.213 ug/mL N.D. N.D. +0.1 -0.5 -1.2
nitrogen source L-Glutamic 10 mM (N) N.D. N.D. +0.1 -0.3 -1.4
stress 7H9 with Norfloxacin 0.125 mM N.D. N.D. -0.2 +0.1 -1.4
stress 7H9 with Moxifloxacin 0.121 ug/mL N.D. N.D. +0.3 -0.0 -1.6
stress 7H9 with Spectinomycin 0.029 mM N.D. N.D. +0.0 +0.4 -1.7
stress 7H9 with Erythromycin 0.016 mM N.D. N.D. +0.0 +0.2 -1.4
stress 7H9 with 8-hydroxy-nitroquinoline 0.03 mM N.D. N.D. -0.1 +0.2 -1.4
stress 7H9 with Spectinomycin 0.029 mM N.D. N.D. -0.1 +0.3 -1.3
stress 7H9 with Levofloxacin 0.3 ug/mL N.D. N.D. +0.1 +0.7 -1.7
nitrogen source L-Glutamic 10 mM (N) N.D. N.D. -0.3 -0.2 +1.2
stress 7H9 with nitrite 1.5 mM; pH 5.5 N.D. N.D. -0.1 -1.1 +2.3
stress 7H9 with Phenazine methosulfate 0.0054 mM N.D. N.D. -0.2 +0.4 +1.1
stress 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM N.D. N.D. +0.0 -0.2 +1.6
carbon source L-Asparagine (C) N.D. N.D. -0.3 +1.4 +0.6
stress 7H9 with Phenazine methosulfate 0.0054 mM N.D. N.D. +0.0 +1.1 +1.0
carbon source L-Asparagine (C) N.D. N.D. -0.3 +1.5 +0.9
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