Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv0527 and Rv0528 are separated by 32 nucleotidesRv0528 and Rv0529 overlap by 4 nucleotidesRv0529 and Rv0530 are separated by 41 nucleotidesRv0530 and Rv0530A overlap by 4 nucleotides Rv0527: Rv0527 - Possible cytochrome C-type biogenesis protein CcdA, at 617,493 to 618,272 Rv0527 Rv0528: Rv0528 - Probable conserved transmembrane protein, at 618,305 to 619,894 Rv0528 Rv0529: Rv0529 - Possible cytochrome C-type biogenesis protein CcsA, at 619,891 to 620,865 Rv0529 Rv0530: Rv0530 - Conserved protein, at 620,907 to 622,124 Rv0530 Rv0530A: Rv0530A - Conserved protein, at 622,121 to 622,282 Rv0530A
Group Condition Rv0527 Rv0528 Rv0529 Rv0530 Rv0530A
stress 7H9 with Hygromycin B 0.0095 mM N.D. N.D. N.D. -0.1 -0.9
carbon source D-Trehalose 10 mM (C) N.D. N.D. N.D. -0.2 -0.6
nitrogen source L-Serine 10 mM (N) N.D. N.D. N.D. +0.1 -0.8
stress 7H9 with Dimethyl Sulfoxide 1 vol% N.D. N.D. N.D. -0.2 -0.5
carbon source L-Lactate 10 mM (C) N.D. N.D. N.D. -0.1 -0.5
stress 7H9 with Meropenem 9.6 ug/mL N.D. N.D. N.D. -0.1 -0.5
stress 7H9 with Hygromycin B 0.0095 mM N.D. N.D. N.D. -0.2 -0.5
stress 7H9 with Sulfamethizole 0.026 mM N.D. N.D. N.D. -0.3 -0.2
nitrogen source Glycine 10 mM (N) N.D. N.D. N.D. +0.1 -0.6
stress 7H9 with Pretomanid 0.213 ug/mL N.D. N.D. N.D. +0.1 -0.5
stress 7H9 with Clofazimine 0.45 ug/mL N.D. N.D. N.D. +0.1 -0.4
nitrogen source L-Serine 10 mM (N) N.D. N.D. N.D. +0.2 -0.5
carbon source D-Lactate 10 mM (C) N.D. N.D. N.D. -0.2 +0.4
carbon source L-Glutamine (C) N.D. N.D. N.D. -0.2 +0.4
carbon source pyruvate (C) N.D. N.D. N.D. -0.1 +0.5
carbon source pyruvate (C) N.D. N.D. N.D. -0.0 +0.5
carbon source casaminos 1 mg/mL (C) N.D. N.D. N.D. -0.1 +0.6
carbon source L-Glutamine (C) N.D. N.D. N.D. -0.1 +0.6
no stress control no stress control N.D. N.D. N.D. +0.0 +0.5
no stress control no stress control N.D. N.D. N.D. +0.2 +0.4
stress 7H9 with Ofloxacin 0.8 ug/mL N.D. N.D. N.D. +0.0 +0.5
stress 7H9 with Isoniazid 0.025 ug/mL N.D. N.D. N.D. +0.4 +0.2
stress 7H9 with Ethionamide 0.1 ug/mL N.D. N.D. N.D. +0.4 +0.3
stress 7H9 with Levofloxacin 0.3 ug/mL N.D. N.D. N.D. +0.1 +0.6
carbon source D,L-Malic Acid 10 mM (C) N.D. N.D. N.D. -0.1 +1.0
stress 7H9 with Isoniazid 0.025 ug/mL N.D. N.D. N.D. +0.6 +0.4
carbon source casaminos 1 mg/mL (C) N.D. N.D. N.D. -0.1 +1.1
carbon source D,L-Malic Acid 10 mM (C) N.D. N.D. N.D. -0.0 +1.1
carbon source L-Asparagine (C) N.D. N.D. N.D. -0.3 +1.4
carbon source L-Asparagine (C) N.D. N.D. N.D. -0.3 +1.5
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Rv0527
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Rv0530A
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