Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv0502 and Rv0503c are separated by 3 nucleotidesRv0503c and Rv0504c are separated by 22 nucleotidesRv0504c and Rv0505c are separated by 161 nucleotidesRv0505c and Rv0506 are separated by 173 nucleotides Rv0502: Rv0502 - Conserved protein, at 592,791 to 593,867 Rv0502 Rv0503c: Rv0503c - Cyclopropane-fatty-acyl-phospholipid synthase 2 CmaA2 (cyclopropane fatty acid synthase) (CFA synthase) (cyclopropane mycolic acid synthase 2) (mycolic acid trans-cyclopropane synthetase), at 593,871 to 594,779 Rv0503c Rv0504c: Rv0504c - Conserved protein, at 594,802 to 595,302 Rv0504c Rv0505c: Rv0505c - Possible phosphoserine phosphatase SerB1 (PSP) (O-phosphoserine phosphohydrolase) (pspase), at 595,464 to 596,585 Rv0505c Rv0506: Rv0506 - Probable conserved membrane protein MmpS2, at 596,759 to 597,202 Rv0506
Group Condition Rv0502 Rv0503c Rv0504c Rv0505c Rv0506
carbon source Glycerol (C) -0.1 -0.3 -5.7 N.D. +0.2
carbon source L-Asparagine (C) -0.1 -0.3 -5.8 N.D. +0.2
stress 7H9 with Ethionamide 0.1 ug/mL +0.7 -0.1 -5.2 N.D. -0.2
stress 7H9 with Meropenem 9.6 ug/mL -0.2 -0.2 -3.9 N.D. -0.1
carbon source L-Aspartic Acid (C) -0.0 -0.1 -3.3 N.D. +0.0
stress 7H9 with Clarithromycin 0.967 ug/mL -0.4 -0.2 -2.7 N.D. -0.1
stress 7H9 with Isoniazid 0.025 ug/mL +0.0 -0.3 -2.7 N.D. -0.2
carbon source D-Glucose (C) -0.1 -0.2 -3.0 N.D. +0.2
stress 7H9 with Clarithromycin 0.967 ug/mL -0.5 -0.1 -2.4 N.D. -0.2
stress 7H9 with Meropenem 9.6 ug/mL +0.0 -0.2 -3.3 N.D. +0.4
stress 7H9 with Ethionamide 0.1 ug/mL +0.4 -0.2 -3.2 N.D. +0.0
carbon source Palmitic 100 uM (C) -0.1 -0.5 -2.4 N.D. +0.2
carbon source Glycerol (C) -0.3 -0.2 -2.2 N.D. +0.1
carbon source D-Glucose (C) -0.3 -0.2 -2.4 N.D. +0.2
carbon source L-Glutamine (C) -0.2 -0.1 -2.4 N.D. +0.1
carbon source acetate (C) -0.0 -0.1 -2.6 N.D. +0.1
stress 7H9 with Clofazimine 0.072 ug/mL +0.1 +0.0 -2.6 N.D. -0.0
stress 7H9 with Rifampicin 0.014 ug/mL +0.1 -0.4 -2.1 N.D. +0.0
nitrogen source L-Asparagine 10 mM (N) -0.2 -0.3 -1.8 N.D. -0.1
carbon source pyruvate (C) -0.0 -0.2 -2.2 N.D. -0.0
nitrogen source L-Aspartic Acid 10 mM (N) -0.0 -0.1 -2.0 N.D. -0.3
stress 7H9 with Clofazimine 0.45 ug/mL +0.1 -0.2 -2.4 N.D. +0.1
nitrogen source L-Alanine 10 mM (N) -0.2 -0.2 -1.6 N.D. -0.2
carbon source L-Aspartic Acid (C) -0.1 -0.2 -1.8 N.D. +0.1
carbon source L-Asparagine (C) +0.1 -0.3 -1.9 N.D. -0.0
carbon source D,L-Malic Acid 10 mM (C) -0.1 -0.0 -2.0 N.D. +0.2
carbon source pyruvate (C) +0.0 -0.1 -1.9 N.D. +0.1
carbon source acetate (C) -0.1 -0.1 -1.8 N.D. +0.1
stress 7H9 with Rifampicin 0.014 ug/mL +0.2 -0.5 -1.3 N.D. -0.1
nitrogen source L-Aspartic Acid 10 mM (N) +0.5 -0.2 -1.8 N.D. -0.0
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