Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv0470A and Rv0471c overlap by 70 nucleotidesRv0471c and Rv0472c are separated by 9 nucleotidesRv0472c and Rv0473 are separated by 136 nucleotidesRv0473 and Rv0474 are separated by 86 nucleotides Rv0470A: Rv0470A - Hypothetical protein, at 561,854 to 562,294 Rv0470A Rv0471c: Rv0471c - Hypothetical protein, at 562,225 to 562,713 Rv0471c Rv0472c: Rv0472c - Probable transcriptional regulatory protein (possibly TetR-family), at 562,723 to 563,427 Rv0472c Rv0473: Rv0473 - Possible conserved transmembrane protein, at 563,564 to 564,934 Rv0473 Rv0474: Rv0474 - Probable transcriptional regulatory protein, at 565,021 to 565,443 Rv0474
Group Condition Rv0470A Rv0471c Rv0472c Rv0473 Rv0474
stress 7H9 with Clofazimine 0.072 ug/mL -0.1 +0.1 -2.5 -0.1 -0.2
nitrogen source L-Serine 10 mM (N) -0.1 -0.1 -1.8 +0.2 -0.9
stress 7H9 with Bedaquiline 0.15 ug/mL -0.0 +0.1 -2.7 +0.1 -0.1
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.1 +0.2 -1.6 -0.1 -1.0
carbon source D-Lactate 10 mM (C) -0.2 -0.1 -1.4 -0.6 -0.3
stress 7H9 with Rifampicin 0.014 ug/mL -0.3 +0.1 -2.4 +0.2 -0.0
stress 7H9 with Clofazimine 0.072 ug/mL -0.1 +0.0 -2.7 +0.3 +0.0
stress 7H9 with Clarithromycin 0.967 ug/mL +0.1 -0.0 -1.9 -0.2 -0.3
stress 7H9 with Bedaquiline 0.15 ug/mL -0.1 +0.2 -2.7 +0.2 -0.0
stress 7H9 with Rifampicin 0.00045 ug/mL -0.0 +0.1 -2.3 +0.0 -0.1
stress 7H9 with Clofazimine 0.45 ug/mL -0.2 +0.1 -2.5 +0.3 +0.2
stress 7H9 with Rifampicin 0.00045 ug/mL -0.0 +0.2 -2.6 +0.2 +0.1
nitrogen source L-Valine 10 mM (N) -0.2 -0.1 -2.0 +0.3 -0.1
stress 7H9 with Delamanid 0.236 ug/mL +0.0 +0.1 -2.1 +0.0 -0.1
stress 7H9 with Clofazimine 0.45 ug/mL +0.0 +0.1 -2.4 +0.3 -0.0
carbon source butyrate 10 mM (C) +0.0 +0.2 -1.7 -0.4 -0.1
carbon source L-Asparagine (C) -0.0 -0.0 -1.7 -0.4 +0.2
stress 7H9 with Rifampicin 0.014 ug/mL -0.4 +0.2 -2.3 +0.4 +0.1
carbon source D-Glucose (C) +0.1 +0.1 -2.0 +0.1 -0.2
nitrogen source L-Serine 10 mM (N) -0.1 +0.1 -1.5 +0.2 -0.5
nitrogen source Glycine 10 mM (N) +0.0 +0.1 -1.8 +0.3 -0.1
carbon source propionate (C) +0.1 +0.0 -2.0 +0.1 +0.1
stress 7H9 with Meropenem 9.6 ug/mL +0.1 +0.2 -1.8 -0.2 +0.2
nitrogen source Glycine 10 mM (N) +0.1 +0.0 -1.7 +0.2 -0.2
carbon source Glycerol (C) +0.1 +0.1 -2.0 +0.3 +0.1
carbon source L-Glutamine (C) +0.0 +0.1 -1.9 +0.4 -0.1
carbon source propionate (C) +0.1 +0.1 -1.8 +0.3 -0.0
stress 7H9 with Meropenem 9.6 ug/mL -0.0 +0.1 -1.7 +0.1 +0.4
nitrogen source L-Aspartic Acid 10 mM (N) +0.0 +0.0 -1.8 +0.7 +0.1
stress 7H9 with Ethionamide 0.1 ug/mL +0.0 -0.0 +1.1 -0.4 -0.8
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