Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv0398c and Rv0399c are separated by 6 nucleotidesRv0399c and Rv0400c are separated by 9 nucleotidesRv0400c and Rv0401 are separated by 35 nucleotidesRv0401 and Rv0402c are separated by 194 nucleotides Rv0398c: Rv0398c - Possible secreted protein, at 476,679 to 477,320 Rv0398c Rv0399c: Rv0399c - Possible conserved lipoprotein LpqK, at 477,327 to 478,556 Rv0399c Rv0400c: Rv0400c - Acyl-CoA dehydrogenase FadE7, at 478,566 to 479,753 Rv0400c Rv0401: Rv0401 - Probable conserved transmembrane protein, at 479,789 to 480,160 Rv0401 Rv0402c: Rv0402c - Probable conserved transmembrane transport protein MmpL1, at 480,355 to 483,231 Rv0402c
Group Condition Rv0398c Rv0399c Rv0400c Rv0401 Rv0402c
stress 7H9 with Clofazimine 0.072 ug/mL -0.2 -0.4 -0.4 N.D. +0.0
stress 7H9 with Rifampicin 0.014 ug/mL -0.5 -0.1 -0.4 N.D. +0.1
stress 7H9 with Pretomanid 0.213 ug/mL -1.1 +0.2 +0.0 N.D. -0.0
carbon source heptadecanoic 250 uM (C) +0.3 -0.7 -0.3 N.D. -0.1
stress 7H9 with Clofazimine 0.072 ug/mL +0.3 -0.8 -0.2 N.D. +0.0
carbon source propionate (C) -0.5 +0.2 -0.4 N.D. -0.0
stress 7H9 with Bedaquiline 0.15 ug/mL -0.6 -0.1 +0.2 N.D. -0.1
carbon source propionate (C) +0.5 -0.1 -1.0 N.D. +0.0
stress 7H9 with Meropenem 9.6 ug/mL -0.4 -0.2 -0.1 N.D. +0.3
carbon source butyrate 10 mM (C) -0.4 -0.3 +0.3 N.D. -0.2
carbon source L-Lactate 10 mM (C) -0.5 -0.1 +0.4 N.D. -0.1
stress 7H9 with Dimethyl Sulfoxide 1 vol% -0.7 +0.0 +0.5 N.D. -0.1
stress 7H9 with Clarithromycin 0.967 ug/mL -0.5 +0.5 -0.0 N.D. -0.0
nitrogen source L-Asparagine 10 mM (N) -0.3 +0.4 +0.2 N.D. -0.1
nitrogen source L-Valine 10 mM (N) -0.4 +0.5 +0.1 N.D. +0.1
stress 7H9 with Streptomycin 0.178 ug/mL -0.1 -0.1 +0.8 N.D. +0.0
no stress control no stress control -0.0 +0.5 +0.4 N.D. -0.1
carbon source L-Lactate 10 mM (C) -0.2 +0.4 +0.5 N.D. +0.1
stress 7H9 with Levofloxacin 0.3 ug/mL +0.5 +0.4 -0.1 N.D. +0.1
no stress control no stress control -0.2 +0.3 +0.8 N.D. +0.0
nitrogen source L-Glutamic 10 mM (N) -0.4 +0.1 +1.2 N.D. +0.1
stress 7H9 with Ethionamide 0.1 ug/mL +0.1 +0.3 +0.6 N.D. -0.0
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.0 +0.5 +0.4 N.D. +0.1
nitrogen source L-Glutamine 10 mM (N) +0.3 -0.1 +0.9 N.D. -0.1
nitrogen source L-Glutamine 10 mM (N) +0.2 -0.3 +1.1 N.D. -0.0
nitrogen source Glycine 10 mM (N) +0.5 +0.3 +0.5 N.D. -0.0
stress 7H9 with Isoniazid 0.025 ug/mL -0.2 +0.7 +0.9 N.D. -0.1
nitrogen source L-Glutamic 10 mM (N) +0.0 +0.0 +1.2 N.D. +0.0
stress 7H9 with Ethionamide 0.1 ug/mL +0.5 +0.8 +0.4 N.D. +0.0
stress 7H9 with Ofloxacin 0.8 ug/mL +0.6 +0.8 +0.5 N.D. +0.2
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Rv0398c
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Rv0399c
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Rv0401
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Rv0402c
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